DGIdb - HYALURONATE SODIUM Drug Record

HYALURONATE SODIUM chembl:CHEMBL2105008 Approved

Alternate Names:

SODIUM HYALURONATE FOR IR IDENTIFICATION
LEGEND
HYALURONIC ACID SODIUM SALT
HYALURONIC ACID
HYALURONATE SODIUM
SODIUM HYALURONATE

Drug Info:

Drug Type	small molecule
Drug Groups	approved
Drug Groups	vet_approved
Drug Categories	adjuvants, immunologic
Drug Categories	carbohydrates
Drug Categories	cicatrizants
Drug Categories	compounds used in a research, industrial, or household setting
Drug Categories	dermatologicals
Drug Categories	glycosaminoglycans
Drug Categories	immunologic factors
Drug Categories	lubricants
Drug Categories	musculo-skeletal system
Drug Categories	nasal preparations
Drug Categories	ophthalmologicals
Drug Categories	polysaccharides
Drug Categories	preparations for treatment of wounds and ulcers
Drug Categories	protective agents
Drug Categories	sensory organs
Drug Categories	surgical aids
Drug Categories	viscoelastic substances
Drug Categories	viscosupplements

(0 More Sources)

Publications:

Wisniewski et al., 1994, TSG-6, an arthritis-associated hyaluronan binding protein, forms a stable complex with the serum protein inter-alpha-inhibitor., Biochemistry
Lee et al., 1992, A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44., J. Cell Biol.
Kohda et al., 1996, Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration., Cell
Turley, 1982, Purification of a hyaluronate-binding protein fraction that modifies cell social behavior., Biochem. Biophys. Res. Commun.
Spicer et al., 2003, A hyaluronan binding link protein gene family whose members are physically linked adjacent to chondroitin sulfate proteoglycan core protein genes: the missing links., J. Biol. Chem.
Arming et al., 1997, In vitro mutagenesis of PH-20 hyaluronidase from human sperm., Eur. J. Biochem.
Bono et al., 2001, Layilin, a novel integral membrane protein, is a hyaluronan receptor., Mol. Biol. Cell
Choi-Miura et al., 2001, Identification of the substrates for plasma hyaluronan binding protein., Biol. Pharm. Bull.
Choi-Miura et al., 1996, Purification and characterization of a novel hyaluronan-binding protein (PHBP) from human plasma: it has three EGF, a kringle and a serine protease domain, similar to hepatocyte growth factor activator., J. Biochem.
Yadav et al., 2009, Evidence for inhibitory interaction of hyaluronan-binding protein 1 (HABP1/p32/gC1qR) with Streptococcus pneumoniae hyaluronidase., J. Biol. Chem.
Prange et al., 1998, Characterization of the human neurocan gene, CSPG3., Gene
Politz et al., 2002, Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues., Biochem. J.
Harris et al., 2007, Expression, processing, and glycosaminoglycan binding activity of the recombinant human 315-kDa hyaluronic acid receptor for endocytosis (HARE)., J. Biol. Chem.
Harris et al., 2008, The human hyaluronan receptor for endocytosis (HARE/Stabilin-2) is a systemic clearance receptor for heparin., J. Biol. Chem.
Zhou et al., 2003, Purification and molecular identification of the human hyaluronan receptor for endocytosis., Glycobiology
Perides et al., 1989, Isolation and partial characterization of a glial hyaluronate-binding protein., J. Biol. Chem.
Bignami et al., 1989, Structural similarity of hyaluronate binding proteins in brain and cartilage., Brain Res. Bull.
Acharya et al., 2000, SPACRCAN, a novel human interphotoreceptor matrix hyaluronan-binding proteoglycan synthesized by photoreceptors and pinealocytes., J. Biol. Chem.
Huang et al., 2000, Molecular characterization of a novel intracellular hyaluronan-binding protein., J. Biol. Chem.

HYALURONATE SODIUM HABP2

Interaction Score: 11.36

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
11217080 8827452

Sources:
DrugBank
HYALURONATE SODIUM HAPLN1

Interaction Score: 11.36

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
12663660 9288901

Sources:
DrugBank
HYALURONATE SODIUM STAB2

Interaction Score: 9.47

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
11829752 17145755 18434317 12626425

Sources:
DrugBank
HYALURONATE SODIUM HABP4

Interaction Score: 7.57

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
10887182

Sources:
DrugBank
HYALURONATE SODIUM IMPG2

Interaction Score: 7.57

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
10702256

Sources:
DrugBank
HYALURONATE SODIUM HAPLN4

Interaction Score: 7.57

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
12663660

Sources:
DrugBank
HYALURONATE SODIUM HAPLN3

Interaction Score: 7.57

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
12663660

Sources:
DrugBank
HYALURONATE SODIUM LAYN

Interaction Score: 7.57

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
11294894

Sources:
DrugBank
HYALURONATE SODIUM TNFAIP6

Interaction Score: 7.57

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
7516184 1730767 8797823

Sources:
DrugBank
HYALURONATE SODIUM VCAN

Interaction Score: 5.68

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
2466833 2469524

Sources:
DrugBank
HYALURONATE SODIUM C1QBP

Interaction Score: 3.79

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
19004836

Sources:
DrugBank
HYALURONATE SODIUM NCAN

Interaction Score: 2.52

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
9795216

Sources:
DrugBank
HYALURONATE SODIUM HMMR

Interaction Score: 1.51

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
6185115

Sources:
DrugBank
HYALURONATE SODIUM CD44

Interaction Score: 0.76

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DrugBank
HYALURONATE SODIUM ICAM1

Interaction Score: 0.47

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DrugBank

DrugBank: DB08818

Version: 5.1.7

Alternate Names:

HYALURONIC ACID DrugBank Drug Name

9004-61-9 CAS Number

AMO Vitrax Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups vet_approved

Publications:

Turley, 1982, Purification of a hyaluronate-binding protein fraction that modifies cell social behavior., Biochem. Biophys. Res. Commun.

Spicer et al., 2003, A hyaluronan binding link protein gene family whose members are physically linked adjacent to chondroitin sulfate proteoglycan core protein genes: the missing links., J. Biol. Chem.

Arming et al., 1997, In vitro mutagenesis of PH-20 hyaluronidase from human sperm., Eur. J. Biochem.

ChemblDrugs: chembl:CHEMBL2105008
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

HYALURONIC ACID	DrugBank Drug Name
9004-61-9	CAS Number
AMO Vitrax	Drug Brand

HYALURONATE SODIUM Drug Record

HYALURONATE SODIUM chembl:CHEMBL2105008 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 11217080 8827452

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 12663660 9288901

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 11829752 17145755 18434317 12626425

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 10887182

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 10702256

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 12663660

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 12663660

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 11294894

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 7516184 1730767 8797823

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 2466833 2469524

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 19004836

Sources: DrugBank

Interaction Types & Directionality: binder

Interaction Info:

PMIDs: 9795216

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 6185115

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DrugBank

DrugBank: DB08818

Alternate Names: HYALURONIC ACID DrugBank Drug Name 9004-61-9 CAS Number AMO Vitrax Drug Brand

Drug Info: Drug Type small molecule Drug Groups approved Drug Groups vet_approved

ChemblDrugs: chembl:CHEMBL2105008

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

binder

PMIDs:
11217080 8827452

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
12663660 9288901

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
11829752 17145755 18434317 12626425

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
10887182

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
10702256

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
12663660

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
12663660

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
11294894

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
7516184 1730767 8797823

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
2466833 2469524

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
19004836

Sources:
DrugBank

Interaction Types & Directionality:

binder

PMIDs:
9795216

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
6185115

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DrugBank

Alternate Names:

HYALURONIC ACID DrugBank Drug Name

9004-61-9 CAS Number

AMO Vitrax Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups vet_approved