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HEXACHLOROPHENE Drug Record

  • Summary
  • Interactions
  • Claims
  • HEXACHLOROPHENE chembl:CHEMBL496 Approved

    Alternate Names:

    E-Z SCRUB
    PHISOHEX
    TURGEX
    HEXACHLOROPHENE
    SEPTI-SOFT
    GERMA-MEDICA
    SCRUBTEAM SURGICAL SPONGEBRUSH
    "GERMA-MEDICA ""MG"""
    PRE-OP II
    GERMA-MEDICA "MG"
    SEPTISOL
    GAMOPHEN
    HEXA-GERM
    PRE-OP
    SOY-DOME
    PHISO-SCRUB
    HEXASCRUB
    SOLU-HEKS
    2,2'-DIHYDROXY-3,3',5,5',6,6'-HEXACHLORODIPHENYLMETHANE
    EXOFENE
    2,2'-METHANEDIYLBIS(3,4,6-TRICHLOROPHENOL)
    HEXABALM
    SUROFENE
    SEPTOFEN
    BIS(3,5,6-TRICHLORO-2-HYDROXYPHENYL)METHANE
    STAPHENE O
    2,2'-DIHYDROXY-3,5,6,3',5',6'-HEXACHLORODIPHENYLMETHANE
    ACIGENA
    SURGI-CEN
    BIS(2-HYDROXY-3,5,6-TRICHLOROPHENYL)METHANE
    DISTODIN
    HEXACLOROFENO
    HEXIDE
    2,2',3,3',5,5'-HEXACHLORO-6,6'-DIHYDROXYDIPHENYLMETHANE
    HEXACHLOROPHENUM
    ARMOHEX
    ESACLOROFENE
    PHISODAN
    ALMEDERM
    HEXAFEN
    STERAL
    STER-ZAC
    2,2'-METHYLENEBIS(3,4,6-TRICHLOROPHENOL)
    HEXACHLOROPHÈNE
    NABAC
    STERASKIN
    SURGI-CIN
    TERSASEPTIC
    GAMOPHENE
    pubchem.compound:3598
    chembl:CHEMBL496
    drugbank:00756
    rxcui:5293
    chemidplus:70-30-4

    Drug Info:

    Drug Categories phenol and derivatives
    Drug Categories chlorophenols
    Drug Categories antiseptics and disinfectants
    Drug Categories drugs causing inadvertant photosensitivity
    Drug Categories photosensitizing agents
    (1 More Sources)

    Publications:

    Jung J et al., 2004, Anti-estrogenic activity of fifty chemicals evaluated by in vitro assays., Life Sci
    Shahian T et al., 2009, Inhibition of a viral enzyme by a small-molecule dimer disruptor., Nat Chem Biol
    Lokanatha et al., 1999, In vitro kinetics of the rat brain succinate dehydrogenase inhibition by hexachlorophene., J. Biochem. Mol. Toxicol.
    Li et al., 2009, Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics., J. Biol. Chem.
    Wang et al., 1978, Inhibition of dehydrogenase enzymes by hexachlorophene., Biochem. Pharmacol.
  • HEXACHLOROPHENE   GZMB

    Interaction Score: 2.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19633659


    Sources:
    DTC

  • HEXACHLOROPHENE   SDHD

    Interaction Score: 1.32

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    10487417


    Sources:
    DrugBank

  • HEXACHLOROPHENE   GLUD1

    Interaction Score: 0.79

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    19531491 570044


    Sources:
    DrugBank

  • HEXACHLOROPHENE   SUMO2

    Interaction Score: 0.66

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   NAPEPLD

    Interaction Score: 0.44

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    GuideToPharmacology

  • HEXACHLOROPHENE   VCP

    Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   NPY1R

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   GALK1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   HSPA8

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   SUMO1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   FASN

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   USP2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   RAPGEF3

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   RAPGEF4

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   MCL1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   ALOX15B

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   PAX8

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   ESR1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15081572


    Sources:
    DTC DrugBank

  • HEXACHLOROPHENE   RORC

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   TSHR

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   THRB

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   KAT2A

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   PPARD

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   ALOX15

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   POLH

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   PLK1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   POLB

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   HTT

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   USP1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   SMAD3

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   HPGD

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   BAZ2B

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   TP53

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   IDH1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   HSD17B10

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   MAPT

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   KDM4A

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   VDR

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   GMNN

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   NFE2L2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   AR

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   CYP3A4

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DrugBank: DB00756

    • Version: 5.1.7

    Alternate Names:
    HEXACHLOROPHENE DrugBank Drug Name
    70-30-4 CAS Number
    Acigena Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups withdrawn

    Publications:
    Jung J et al., 2004, Anti-estrogenic activity of fifty chemicals evaluated by in vitro assays., Life Sci
    Lokanatha et al., 1999, In vitro kinetics of the rat brain succinate dehydrogenase inhibition by hexachlorophene., J. Biochem. Mol. Toxicol.
    Li et al., 2009, Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics., J. Biol. Chem.

  • DTC: HEXACHLOROPHENE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL496 ChEMBL Drug ID

    Drug Info:

    Publications:
    Shahian T et al., 2009, Inhibition of a viral enzyme by a small-molecule dimer disruptor., Nat Chem Biol

  • TTD: Hexachlorophene

    • Version: 2020.06.01

    Alternate Names:
    D0ZX2G TTD Drug ID

    Drug Info:

    Publications:

  • GuideToPharmacology: 405560510

    • Version: 29-September-2020

    Alternate Names:
    HEXACHLOROPHENE GuideToPharmacology Ligand Name

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL496

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2021-04-13