DGIdb - HEXACHLOROPHENE Drug Record

HEXACHLOROPHENE chembl:CHEMBL496 Approved

Alternate Names:

E-Z SCRUB
PHISOHEX
TURGEX
HEXACHLOROPHENE
SEPTI-SOFT
GERMA-MEDICA
SCRUBTEAM SURGICAL SPONGEBRUSH
"GERMA-MEDICA ""MG"""
PRE-OP II
GERMA-MEDICA "MG"
SEPTISOL
GAMOPHEN
HEXA-GERM
PRE-OP
SOY-DOME
PHISO-SCRUB
HEXASCRUB
SOLU-HEKS
2,2'-DIHYDROXY-3,3',5,5',6,6'-HEXACHLORODIPHENYLMETHANE
EXOFENE
2,2'-METHANEDIYLBIS(3,4,6-TRICHLOROPHENOL)
HEXABALM
SUROFENE
SEPTOFEN
BIS(3,5,6-TRICHLORO-2-HYDROXYPHENYL)METHANE
STAPHENE O
2,2'-DIHYDROXY-3,5,6,3',5',6'-HEXACHLORODIPHENYLMETHANE
ACIGENA
SURGI-CEN
BIS(2-HYDROXY-3,5,6-TRICHLOROPHENYL)METHANE
DISTODIN
HEXACLOROFENO
HEXIDE
2,2',3,3',5,5'-HEXACHLORO-6,6'-DIHYDROXYDIPHENYLMETHANE
HEXACHLOROPHENUM
ARMOHEX
ESACLOROFENE
PHISODAN
ALMEDERM
HEXAFEN
STERAL
STER-ZAC
2,2'-METHYLENEBIS(3,4,6-TRICHLOROPHENOL)
HEXACHLOROPHÈNE
NABAC
STERASKIN
SURGI-CIN
TERSASEPTIC
GAMOPHENE
pubchem.compound:3598
chembl:CHEMBL496
drugbank:00756
rxcui:5293
chemidplus:70-30-4

Drug Info:

Drug Categories	phenol and derivatives
Drug Categories	chlorophenols
Drug Categories	antiseptics and disinfectants
Drug Categories	drugs causing inadvertant photosensitivity
Drug Categories	photosensitizing agents

(1 More Sources)

Publications:

Jung J et al., 2004, Anti-estrogenic activity of fifty chemicals evaluated by in vitro assays., Life Sci
Shahian T et al., 2009, Inhibition of a viral enzyme by a small-molecule dimer disruptor., Nat Chem Biol
Lokanatha et al., 1999, In vitro kinetics of the rat brain succinate dehydrogenase inhibition by hexachlorophene., J. Biochem. Mol. Toxicol.
Li et al., 2009, Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics., J. Biol. Chem.
Wang et al., 1978, Inhibition of dehydrogenase enzymes by hexachlorophene., Biochem. Pharmacol.

HEXACHLOROPHENE GZMB

Interaction Score: 2.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19633659

Sources:
DTC
HEXACHLOROPHENE SDHD

Interaction Score: 1.32

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
10487417

Sources:
DrugBank
HEXACHLOROPHENE GLUD1

Interaction Score: 0.79

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
19531491 570044

Sources:
DrugBank
HEXACHLOROPHENE SUMO2

Interaction Score: 0.66

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE NAPEPLD

Interaction Score: 0.44

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
HEXACHLOROPHENE VCP

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE NPY1R

Interaction Score: 0.17

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE GALK1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE HSPA8

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE SUMO1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE FASN

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE USP2

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE RAPGEF3

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE RAPGEF4

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE MCL1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE ALOX15B

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE PAX8

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE ESR1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15081572

Sources:
DTC DrugBank
HEXACHLOROPHENE RORC

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE TSHR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE THRB

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE KAT2A

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE PPARD

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE ALOX15

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE POLH

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE PLK1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE POLB

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE HTT

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE USP1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE SMAD3

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE HPGD

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE BAZ2B

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE TP53

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE IDH1

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE HSD17B10

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE MAPT

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE KDM4A

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE GMNN

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE NFE2L2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE AR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE CYP3A4

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

DrugBank: DB00756

Version: 5.1.7

Alternate Names:

HEXACHLOROPHENE DrugBank Drug Name

70-30-4 CAS Number

Acigena Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups withdrawn

Publications:

Jung J et al., 2004, Anti-estrogenic activity of fifty chemicals evaluated by in vitro assays., Life Sci

Lokanatha et al., 1999, In vitro kinetics of the rat brain succinate dehydrogenase inhibition by hexachlorophene., J. Biochem. Mol. Toxicol.

Li et al., 2009, Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics., J. Biol. Chem.

DTC: HEXACHLOROPHENE
- Version: 02-September-2020
Alternate Names:

CHEMBL496 ChEMBL Drug ID

Drug Info:

Publications:

Shahian T et al., 2009, Inhibition of a viral enzyme by a small-molecule dimer disruptor., Nat Chem Biol
TTD: Hexachlorophene
- Version: 2020.06.01
Alternate Names:

D0ZX2G TTD Drug ID

Drug Info:

Publications:
GuideToPharmacology: 405560510
- Version: 29-September-2020
Alternate Names:

HEXACHLOROPHENE GuideToPharmacology Ligand Name

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL496
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Specific Action of the Ligand	Inhibition
Endogenous Drug?	False
Direct Interaction?	False

HEXACHLOROPHENE	DrugBank Drug Name
70-30-4	CAS Number
Acigena	Drug Brand

Drug Type	small molecule
Drug Groups	approved
Drug Groups	withdrawn

HEXACHLOROPHENE Drug Record

HEXACHLOROPHENE chembl:CHEMBL496 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19633659

Sources: DTC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 10487417

Sources: DrugBank

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 19531491 570044

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15081572

Sources: DTC DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Interaction Types & Directionality:

n/a

PMIDs:
19633659

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
10487417

Sources:
DrugBank

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
19531491 570044

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
15081572

Sources:
DTC DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a