HALOTHANE |
RHIDIALOTHAN |
FLUOTHANE |
BROMOCHLOROTRIFLUOROETHANE |
2,2,2-TRIFLUORO-1-CHLORO-1-BROMOETHANE |
1,1,1-TRIFLUORO-2-CHLORO-2-BROMOETHANE |
2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE |
PHTHOROTHANUM |
1-BROMO-1-CHLORO-2,2,2-TRIFLUOROETHANE |
1,1,1-TRIFLUORO-2-BROMO-2-CHLOROETHANE |
HALON-2311 |
NARCOTANE |
RHODIALOTHAN |
drugbank:01159 |
chemidplus:151-67-7 |
chembl:CHEMBL931 |
rxcui:5095 |
pubchem.compound:3562 |
Year of Approval | 1958 |
Drug Class | anesthetics, inhalation |
FDA Approval | 1958 |
Drug Class | small molecule |
Drug Indications | Anesthetics, Inhalation |
Drug Categories | agents that produce hypertension |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | nmda receptor antagonists |
n/a |
inhibitor (inhibitory) |
Specific Action of the Ligand | None |
Details of Interaction | studied at ~5 mM |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Specific Action of the Ligand | None |
Endogenous Drug? | False |
Direct Interaction? | False |
n/a |
Trial Name | - |
Novel drug target | Established target |
activator (activating) |
binder |
Direct Interaction? | True |
Endogenous Drug? | False |
Details of Interaction | studied at 1-5 mM |
activator (activating) |
binder |
Specific Action of the Ligand | None |
Details of Interaction | studied at 1-10 mM |
Endogenous Drug? | False |
activator (activating) |
Endogenous Drug? | False |
Specific Action of the Ligand | None |
activator (activating) |
Direct Interaction? | True |
Endogenous Drug? | False |
Details of Interaction | studied at 1-5 mM |
n/a |
Mechanism of Interaction | Potassium channel subfamily K member 18 opener |
Direct Interaction | yes |
activator (activating) |
Mechanism of Interaction | Potassium channel subfamily K member 2 opener |
Direct Interaction | yes |
Specific Action of the Ligand | None |
allosteric modulator |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) positive modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) positive modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
HALOTHANE | DrugBank Drug Name |
151-67-7 | CAS Number |
Fluothane | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Groups | vet_approved |
HALOTHANE | Primary Drug Name |
Drug Class | anesthetics, inhalation |
Year of Approval | 1958 |
Drug Indications | Anesthetics, Inhalation |
Drug Class | small molecule |
FDA Approval | 1958 |
D0D8VE | TTD Drug ID |
CHEMBL931 | ChEMBL Drug ID |
HALOTHANE | GuideToPharmacology Ligand Name |