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GLUTAMINE Drug Record

  • Summary
  • Interactions
  • Claims
  • GLUTAMINE chembl:CHEMBL930 Approved

    Alternate Names:

    L-GLUTAMINE
    LEVOGLUTAMIDE
    FEMA NO. 3684
    ENDARI
    GLUTAMINE
    NSC-27421
    NUTRESTORE
    (2S)-2,5-DIAMINO-5-OXOPENTANOIC ACID
    L-GLUTAMIC ACID GAMMA-AMIDE
    L-(+)-GLUTAMINE
    GLN
    (2S)-2-AMINO-4-CARBAMOYLBUTANOIC ACID
    L-GLUTAMIC ACID Γ-AMIDE
    GLUTAMIC ACID 5-AMIDE
    L-GLUTAMIN
    L-GLUTAMINSAEURE-5-AMID
    GLUTAMIC ACID AMIDE
    (S)-2,5-DIAMINO-5-OXOPENTANOIC ACID
    L-2-AMINOGLUTARAMIC ACID
    L-GLUTAMINSÄURE-5-AMID
    Q
    chemidplus:56-85-9
    rxcui:4885
    drugbank:00130
    chembl:CHEMBL930
    pubchem.compound:5961

    Drug Info:

    (0 More Sources)

    Publications:

    Zhou et al., 2006, [The effect of glutamine on the growth, metabolism and endostatin production of microencapsulated rCHO cells]., Sheng Wu Gong Cheng Xue Bao
    Todorova et al., 2006, Modulation of p53 and c-myc in DMBA-induced mammary tumors by oral glutamine., Nutr Cancer
    Wasa et al., 2002, Characterization of L-glutamine transport by a human neuroblastoma cell line., Am. J. Physiol., Cell Physiol.
    Meng et al., 2004, Insulin-like growth factor-2 activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases., J. Gastrointest. Surg.
    Squires et al., 1997, Regulation of hepatic glutaminase in the streptozotocin-induced diabetic rat., Diabetes
    Noguchi et al., 1997, Increased glutamine consumption in small intestine epithelial cells during sepsis in rats., Am. J. Surg.
    Smith et al., 1984, Regulation of glutamine synthetase and glutaminase activities in cultured skeletal muscle cells., J. Cell. Physiol.
    Castell et al., 2004, Granule localization of glutaminase in human neutrophils and the consequence of glutamine utilization for neutrophil activity., J. Biol. Chem.
    Kovacević, 1975, Possible mechanisms of the efflux of glutamate from kidney mitochondria generated by the activity of mitochondrial glutaminase., Biochim. Biophys. Acta
    Curthoys, 2001, Role of mitochondrial glutaminase in rat renal glutamine metabolism., J. Nutr.
    Huang et al., 1999, Induction of gadd153 mRNA by nutrient deprivation is overcome by glutamine., Biochem. J.
  • GLUTAMINE   SLC1A5

    Interaction Score: 20.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11997238


    Sources:
    NCI

  • GLUTAMINE   COL18A1

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16572858


    Sources:
    NCI

  • GLUTAMINE   IGF2

    Interaction Score: 1.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14746834


    Sources:
    NCI

  • GLUTAMINE   GLS

    Interaction Score: 1.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9392478 9124626 6146632 14722097 1174515 11533299


    Sources:
    NCI

  • GLUTAMINE   DDIT3

    Interaction Score: 0.79

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10377266


    Sources:
    NCI

  • GLUTAMINE   MYC

    Interaction Score: 0.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16898871


    Sources:
    NCI

  • NCI: GLUTAMINE

    • Version: 14-September-2017

    Alternate Names:
    C522 NCI drug code

    Drug Info:

    Publications:
    Noguchi et al., 1997, Increased glutamine consumption in small intestine epithelial cells during sepsis in rats., Am. J. Surg.
    Smith et al., 1984, Regulation of glutamine synthetase and glutaminase activities in cultured skeletal muscle cells., J. Cell. Physiol.
    Squires et al., 1997, Regulation of hepatic glutaminase in the streptozotocin-induced diabetic rat., Diabetes

  • NCI: L-GLUTAMINE

    • Version: 14-September-2017

    Alternate Names:
    C522 NCI drug code

    Drug Info:

    Publications:
    Meng et al., 2004, Insulin-like growth factor-2 activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases., J. Gastrointest. Surg.

  • NCI: GLN

    • Version: 14-September-2017

    Alternate Names:
    C522 NCI drug code

    Drug Info:

    Publications:
    Todorova et al., 2006, Modulation of p53 and c-myc in DMBA-induced mammary tumors by oral glutamine., Nutr Cancer

  • ChemblDrugs: chembl:CHEMBL930

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21