• Interaction Score: 3.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25210794


    Sources:
    CIViC

  • Interaction Score: 1.58

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 0.44

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name STA-9090
    Novel drug target Novel Target
    Mechanism of Interaction Heat shock protein HSP90 inhibitor

  • Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type skin melanoma
    Response Type sensitive
    Approval Status Preclinical - Cell line xenograft


    Sources:
    JAX-CKB

  • Interaction Score: 0.14

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Heat shock protein HSP90 inhibitor
    Direct Interaction yes
    Trial Name STA-9090

  • Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type non-small cell lung carcinoma
    Response Type predicted – sensitive
    Approval Status Preclinical - Cell culture

    PMIDs:
    26483207


    Sources:
    JAX-CKB

  • Interaction Score: 0.11

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Afatinib + Ganetespib
    combination therapy Erlotinib + Ganetespib
    Indication/Tumor Type non-small cell lung carcinoma

    PMIDs:
    25077897


    Sources:
    JAX-CKB

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type prostate cancer
    Response Type resistant
    Approval Status Preclinical

    PMIDs:
    26009011


    Sources:
    JAX-CKB