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ETIDRONIC ACID Drug Record

  • Summary
  • Interactions
  • Claims
  • ETIDRONIC ACID chembl:CHEMBL871 Approved

    Alternate Names:

    ETIDRONATE
    ETIDRONIC ACID
    DIDRONEL
    NSC-227995
    M05BA01
    (1-HYDROXYETHYLIDENE)DIPHOSPHONIC ACID
    1-HYDROXYETHANE-1,1-BISPHOSPHONIC ACID
    (1-HYDROXYETHYLENE)DIPHOSPHONIC ACID
    HYDROXYETHANEDIPHOSPHONIC ACID
    ETHANE-1-HYDROXY-1,1-BISPHOSPHONIC ACID
    ETHANE-1-HYDROXY-1,1-DIPHOSPHONATE
    1-HYDROXYETHANE-1,1-DIPHOSPHONIC ACID
    ACETODIPHOSPHONIC ACID
    (1-HYDROXY-ETHYLIDENE)DIPHOSPHONIC ACID
    OXYETHYLIDENEDIPHOSPHONIC ACID
    EHDP
    (1-HYDROXYETHYLIDENE)BIS(PHOSPHONIC ACID)
    ETHANE-1-HYDROXY-1,1-BISPHOSPHONATE
    ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID
    1,1,1-ETHANETRIOL DIPHOSPHONATE
    1-HYDROXY-1,1-DIPHOSPHONOETHANE
    (1-HYDROXYETHYLIDENE)BISPHOSPHONIC ACID
    1-HYDROXYETHANEDIPHOSPHONIC ACID
    1-HYDROXYETHYLIDENE-1,1-BISPHOSPHONATE
    ACIDUM ETIDRONICUM
    DIDRONEL®
    1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID
    ETIDRONSÄURE
    1-HYDROXYETHANE-1,1-DIPHOSPHONATE
    ETIDRONATE DISODIUM
    1-HYDROXYETHANE 1,1-DIPHOSPHONIC ACID
    (HYDROXYETHYLIDENE)DIPHOSPHONIC ACID
    HEDP
    ÁCIDO ETIDRÓNICO
    ACIDE ÉTIDRONIQUE
    chemidplus:2809-21-4
    chembl:CHEMBL871
    drugbank:01077
    rxcui:1356715
    pubchem.compound:3305
    rxcui:42682

    Drug Info:

    (0 More Sources)

    Publications:

    Ongphiphadhanakul et al., 1993, Etidronate inhibits the thyroid hormone-induced bone loss in rats assessed by bone mineral density and messenger ribonucleic acid markers of osteoblast and osteoclast function., Endocrinology
    Yamamoto et al., 2006, Inhibitory effect of bone resorption and inflammation with etidronate therapy in patients with rheumatoid arthritis for 3 years and in vitro assay in arthritis models., Rheumatol. Int.
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Engel et al., 2003, Alendronate and etidronate do not regulate interleukin 6 and 11 synthesis in normal human osteoblasts in culture., Calcif. Tissue Int.
  • ETIDRONIC ACID   SMPD1

    Interaction Score: 3.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ETIDRONIC ACID   IL11

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12522661


    Sources:
    NCI

  • ETIDRONIC ACID   TAC1

    Interaction Score: 0.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16133581


    Sources:
    NCI

  • ETIDRONIC ACID   BGLAP

    Interaction Score: 0.6

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8243271


    Sources:
    NCI

  • ETIDRONIC ACID   CYP2C9

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • ETIDRONIC ACID   CYP2C19

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • ETIDRONIC ACID   CYP1A2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • ETIDRONIC ACID   CYP2D6

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • ETIDRONIC ACID   CYP3A4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • NCI: EHDP

    • Version: 14-September-2017

    Alternate Names:
    C1332 NCI drug code

    Drug Info:

    Publications:
    Ongphiphadhanakul et al., 1993, Etidronate inhibits the thyroid hormone-induced bone loss in rats assessed by bone mineral density and messenger ribonucleic acid markers of osteoblast and osteoclast function., Endocrinology

  • NCI: ETIDRONATE

    • Version: 14-September-2017

    Alternate Names:
    C1332 NCI drug code

    Drug Info:

    Publications:
    Yamamoto et al., 2006, Inhibitory effect of bone resorption and inflammation with etidronate therapy in patients with rheumatoid arthritis for 3 years and in vitro assay in arthritis models., Rheumatol. Int.
    Engel et al., 2003, Alendronate and etidronate do not regulate interleukin 6 and 11 synthesis in normal human osteoblasts in culture., Calcif. Tissue Int.

  • DTC: ETIDRONIC ACID

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL871 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

  • ChemblDrugs: chembl:CHEMBL871

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21