DGIdb - EPINEPHRINE Drug Record

EPINEPHRINE chembl:CHEMBL679 Approved

Alternate Names:

ASTHMAHALER
EPPY
JEXT
RIDDOFAN
BRONKAID MIST
MEDIHALER-EPI
SUS-PHRINE SULFITE FREE
ANA-GUARD
ADREN CO
EMERADE
ADRENALINE
ADRENACLICK
SYMJEPI
TWINJECT 0.15
GPPE INH SOLN
AUVI-Q
ANA-KIT
EPIPEN JR.
RYBARVIN
EPI E Z PEN JR
SUS-PHRINE
EPINEPHRINE HCL
EPIPEN
EPIPEN E Z PEN
ANAPHYLACTIC SHOCK DRUG KIT
NSC-62786
EPIPEN JR
ADRENALIN
EPINEPHRINE
ASMA-VYDRIN
SIMPLENE
BROVON
RIDDOBRON
SOLN MADE TO RYBARVIN FOR
SUS-PHRINE SULFITE-FREE
TWINJECT 0.3
TWINJECT
PRIMATENE MIST
ANAPEN
LEVO-METHYLAMINOETHANOLCATECHOL
PRIMATENE
(R)-(-)-ADNEPHRINE
LEVOEPINEPHRINE
(R)-EPINEPHRINE
(-)-ADRENALINE
(-)-EPINEPHRINE
(R)-(-)-EPIRENAMINE
L-EPINEPHRINE
(R)-(-)-EPINEPHRINE
(-)-3,4-DIHYDROXY-ALPHA-[(METHYLAMINO)METHYL]BENZYL ALCOHOL(-)-3,4-DIHYDROXY-ALPHA-[(METHYLAMINO)METHYL]-BENZYL ALCOHOL
4-[(1R)-1-HYDROXY-2-METHYLAMINOETHYL]BENZENE-1,2-DIOL
(R)-(-)-ADRENALINE
L-ADRENALINE
(-)-3,4-DIHYDROXY-ALPHA-[(METHYLAMINO)METHYL]-BENZYL ALCOHOL
4-[(1R)-1-HYDROXY-2-METHYLAMINO-ETHYL]PYROCATECHOL
(-)-3,4-DIHYDROXY-ALPHA-[2-(METHYLAMINO)ETHYL]BENZYL ALCOHOL
(R)-4-[1-HYDROXY-2-(METHYLAMINO)ETHYL]-1,2-BENZENEDIOL
(−)-ADRENALINE
L-DETHYLAMINOETHANOLCATECHOL
(R)-ADRENALINE
(-)-3,4-DIHYDROXY-A-[2-(METHYLAMINO)ETHYL]BENZYL ALCOHOL
L-1-(3,4-DIHYDROXYPHENYL)-2-METHYLAMINOETHANOL
R-(-)-EPINEPHRINE
4-[(1R)-1-HYDROXY-2-METHYLAMINO-ETHYL]BENZENE-1,2-DIOL
4-[(1R)-1-HYDROXY-2-(METHYLAMINO)ETHYL]-1,2-BENZENEDIOL
(-)-(R)-EPINEPHRINE
L-EPIRENAMINE
(R)-(−)-ADRENALINE
chembl:CHEMBL679
rxcui:3992
pubchem.compound:5816
chemidplus:51-43-4
drugbank:00668

Drug Info:

FDA Approval	approved
Drug Class	Small Molecule
Drug Indications	anestethic
Drug Class	vasoconstrictor agents
Drug Class	bronchodilator agents
Year of Approval	approved before 1982

(5 More Sources)

Publications:

Jensen et al., 2010, Functional alpha-1B adrenergic receptors on human epicardial coronary artery endothelial cells., Naunyn Schmiedebergs Arch. Pharmacol.
Du et al., 2010, Modeling the interactions between alpha(1)-adrenergic receptors and their antagonists., Curr Comput Aided Drug Des
Cotecchia, 2010, The α1-adrenergic receptors: diversity of signaling networks and regulation., J. Recept. Signal Transduct. Res.
Shieh et al., 2009, Epinephrine, phenylephrine, and methoxamine induce infiltrative anesthesia via alpha1-adrenoceptors in rats., Acta Pharmacol. Sin.
Hayasaka et al., 1978, Effects of epinephrine, indomethacin, acetylsalicyclic acid, dexamethasone, and cyclic AMP on the in vitro activity of lysosomal hyaluronidase from the rabbit iris., Invest. Ophthalmol. Vis. Sci.
Sanbe et al., 2007, Alpha1-adrenoceptors are required for normal male sexual function., Br. J. Pharmacol.
Tomiyama et al., 2007, Expressions and mechanical functions of alpha1-adrenoceptor subtypes in hamster ureter., Eur. J. Pharmacol.
Bylund, 1992, Subtypes of alpha 1- and alpha 2-adrenergic receptors., FASEB J.
Nash, 1990, Alpha-adrenergic blockers: mechanism of action, blood pressure control, and effects of lipoprotein metabolism., Clin Cardiol
Gobbi et al., 1990, The modulation of [3H]noradrenaline and [3H]serotonin release from rat brain synaptosomes is not mediated by the alpha 2B-adrenoceptor subtype., Naunyn Schmiedebergs Arch. Pharmacol.
Rudling et al., 2000, A comparison of agonist-specific coupling of cloned human alpha(2)-adrenoceptor subtypes., Br. J. Pharmacol.
Vizi et al., 2001, Evidence for presynaptic cannabinoid CB(1) receptor-mediated inhibition of noradrenaline release in the guinea pig lung., Eur. J. Pharmacol.
Gilsbach et al., 2008, Presynaptic metabotropic receptors for acetylcholine and adrenaline/noradrenaline., Handb Exp Pharmacol
Ariëns EJ et al., 1983, Physiological and pharmacological aspects of adrenergic receptor classification., Biochem Pharmacol
Takeuchi et al., 2001, Adrenergic stimulation of osteoclastogenesis mediated by expression of osteoclast differentiation factor in MC3T3-E1 osteoblast-like cells., Biochem. Pharmacol.
Patil et al., 2008, Analysis of efficacy of chiral adrenergic agonists., Chirality
Young et al., 2002, Effects of rearing temperature on sympathoadrenal activity in young adult rats., Am. J. Physiol. Regul. Integr. Comp. Physiol.
Ozakca et al., 2007, Role of beta-3-adrenoceptor in catecholamine-induced relaxations in gastric fundus from control and diabetic rats., Pharmacology
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Leineweber et al., 2007, In patients chronically treated with metoprolol, the demand of inotropic catecholamine support after coronary artery bypass grafting is determined by the Arg389Gly-beta 1-adrenoceptor polymorphism., Naunyn Schmiedebergs Arch. Pharmacol.
Strosberg AD, 1993, Structure, function, and regulation of adrenergic receptors., Protein Sci
Khasar SG et al., 1999, Epinephrine produces a beta-adrenergic receptor-mediated mechanical hyperalgesia and in vitro sensitization of rat nociceptors., J Neurophysiol
Hieble et al., 1998, Molecular basis for the stereoselective interactions of catecholamines with alpha-adrenoceptors., Proc. West. Pharmacol. Soc.
Giovannoni et al., 2009, Alpha2-agonists as analgesic agents., Med Res Rev
Nyrönen et al., 2001, Molecular mechanism for agonist-promoted alpha(2A)-adrenoceptor activation by norepinephrine and epinephrine., Mol. Pharmacol.
MacLennan et al., 2000, Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using extracellular acidification rate changes., Br. J. Pharmacol.
Prenner et al., 2007, Reduction of high-affinity beta2-adrenergic receptor binding by hyperforin and hyperoside on rat C6 glioblastoma cells measured by fluorescence correlation spectroscopy., Biochemistry
Lucin et al., 2007, Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation., Exp. Neurol.
Reiner S et al., 2010, Differential signaling of the endogenous agonists at the beta2-adrenergic receptor., J Biol Chem
Lova et al., 2003, A selective role for phosphatidylinositol 3,4,5-trisphosphate in the Gi-dependent activation of platelet Rap1B., J. Biol. Chem.
Saeed et al., 2004, Signaling mechanisms mediated by G-protein coupled receptors in human platelets., Acta Pharmacol. Sin.
Mundinger et al., 2006, Direct stimulation of ghrelin secretion by sympathetic nerves., Endocrinology
Ertbjerg et al., 2000, Epinephrine upregulates calpain activity in cultured C2C12 muscle cells., Biochimie

EPINEPHRINE HYAL2

Interaction Score: 2.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
212383

Sources:
NCI
EPINEPHRINE CAST

Interaction Score: 1.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10863002

Sources:
NCI
EPINEPHRINE TNFRSF11B

Interaction Score: 0.85

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11239501

Sources:
NCI
EPINEPHRINE TPM3

Interaction Score: 0.53

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18172836

Sources:
NCI
EPINEPHRINE GHRL

Interaction Score: 0.35

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16527847

Sources:
NCI
EPINEPHRINE ADRA2B

Interaction Score: 0.27

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Novel drug target Established target

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
1980236 1979424 11053214 11728431 18064417 6134529

Sources:
TdgClinicalTrial ChemblInteractions PharmGKB
EPINEPHRINE ADRA1D

Interaction Score: 0.27

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Novel drug target Established target

PMIDs:
20857090 20412040 20954794 19730427

Sources:
TdgClinicalTrial PharmGKB
EPINEPHRINE ADRA2A

Interaction Score: 0.25

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Novel drug target Established target

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
1980236 9836297 18680204 11306720 10742288 18064417 6134529

Sources:
TdgClinicalTrial ChemblInteractions PharmGKB
EPINEPHRINE ADRB1

Interaction Score: 0.23

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
17622774 11752352 17541557 8401205 10085337

Sources:
TdgClinicalTrial ChemblInteractions TEND PharmGKB TTD
EPINEPHRINE ADRA1B

Interaction Score: 0.19

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Adrenergic receptor agonist

Direct Interaction yes

Novel drug target Established target

PMIDs:
20857090 20412040 20954794 19730427

Sources:
TdgClinicalTrial ChemblInteractions PharmGKB
EPINEPHRINE ADRA1A

Interaction Score: 0.16

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Adrenergic receptor agonist

Direct Interaction yes

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

PMIDs:
20857090 17603545 17658513 20412040

Sources:
TdgClinicalTrial ChemblInteractions TEND PharmGKB
EPINEPHRINE MAPK10

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15210061

Sources:
NCI
EPINEPHRINE ADRB2

Interaction Score: 0.14

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Novel drug target Established target

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
17417877 17622774 11752352 17597612 20837485

Sources:
TdgClinicalTrial ChemblInteractions TEND PharmGKB
EPINEPHRINE SLC2A4

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12376414

Sources:
NCI
EPINEPHRINE ADRA2C

Interaction Score: 0.08

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
1346768

Sources:
ChemblInteractions PharmGKB
EPINEPHRINE PIK3CB

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12407113

Sources:
NCI
EPINEPHRINE ADRB3

Interaction Score: 0.06

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Adrenergic receptor agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
EPINEPHRINE G6PD

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

Combination therapy Articaine,Epinephrine

PMIDs:
None found

Sources:
FDA
EPINEPHRINE MTOR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE HIF1A

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE DRD1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE RECQL

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE APEX1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE FEN1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE POLK

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE KDM4E

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE HSD17B10

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE MAPT

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE NFE2L2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

TEND: EPINEPHRINE
- Version: 01-August-2011
Alternate Names:

Drug Info:

Year of Approval approved before 1982

Drug Class bronchodilator agents

Drug Class vasoconstrictor agents

Publications:
TdgClinicalTrial: EPINEPHRINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications anestethic

Drug Class Small Molecule

FDA Approval approved

Publications:

NCI: EPINEPHRINE

Version: 14-September-2017

Alternate Names:

C473 NCI drug code

Drug Info:

Publications:

Hayasaka et al., 1978, Effects of epinephrine, indomethacin, acetylsalicyclic acid, dexamethasone, and cyclic AMP on the in vitro activity of lysosomal hyaluronidase from the rabbit iris., Invest. Ophthalmol. Vis. Sci.

Ertbjerg et al., 2000, Epinephrine upregulates calpain activity in cultured C2C12 muscle cells., Biochimie

Takeuchi et al., 2001, Adrenergic stimulation of osteoclastogenesis mediated by expression of osteoclast differentiation factor in MC3T3-E1 osteoblast-like cells., Biochem. Pharmacol.

TTD: Epinephrine
- Version: 2020.06.01
Alternate Names:

D04PHC TTD Drug ID

Drug Info:

Publications:
DTC: EPINEPHRINE
- Version: 02-September-2020
Alternate Names:

CHEMBL679 ChEMBL Drug ID

Drug Info:

Publications:
FDA: Epinephrine
- Version: 04-September-2020
Alternate Names:

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL679
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL679
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:
PharmGKB: epinephrine
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Trial Name	transdermal lidocaine/epinephrine patch,Lidosite
Novel drug target	Established target
Mechanism of Interaction	Adrenergic receptor agonist

Mechanism of Interaction	Adrenergic receptor agonist
Direct Interaction	yes
Novel drug target	Established target

EPINEPHRINE Drug Record

EPINEPHRINE chembl:CHEMBL679 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 212383

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10863002

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11239501

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 18172836

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16527847

Sources: NCI

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name transdermal lidocaine/epinephrine patch,Lidosite Novel drug target Established target Mechanism of Interaction Adrenergic receptor agonist

PMIDs: 1980236 1979424 11053214 11728431 18064417 6134529

Sources: TdgClinicalTrial ChemblInteractions PharmGKB

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name transdermal lidocaine/epinephrine patch,Lidosite Novel drug target Established target

PMIDs: 20857090 20412040 20954794 19730427

Sources: TdgClinicalTrial PharmGKB

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name transdermal lidocaine/epinephrine patch,Lidosite Novel drug target Established target Mechanism of Interaction Adrenergic receptor agonist

PMIDs: 1980236 9836297 18680204 11306720 10742288 18064417 6134529

Sources: TdgClinicalTrial ChemblInteractions PharmGKB

Interaction Types & Directionality: agonist (activating)

Interaction Info: Novel drug target Established target Trial Name transdermal lidocaine/epinephrine patch,Lidosite Mechanism of Interaction Adrenergic receptor agonist

PMIDs: 17622774 11752352 17541557 8401205 10085337

Sources: TdgClinicalTrial ChemblInteractions TEND PharmGKB TTD

Interaction Types & Directionality: agonist (activating)

Interaction Info: Mechanism of Interaction Adrenergic receptor agonist Direct Interaction yes Novel drug target Established target

PMIDs: 20857090 20412040 20954794 19730427

Sources: TdgClinicalTrial ChemblInteractions PharmGKB

Interaction Types & Directionality: agonist (activating)

Interaction Info: Mechanism of Interaction Adrenergic receptor agonist Direct Interaction yes Trial Name transdermal lidocaine/epinephrine patch,Lidosite

PMIDs: 20857090 17603545 17658513 20412040

Sources: TdgClinicalTrial ChemblInteractions TEND PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15210061

Sources: NCI

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name transdermal lidocaine/epinephrine patch,Lidosite Novel drug target Established target Mechanism of Interaction Adrenergic receptor agonist

PMIDs: 17417877 17622774 11752352 17597612 20837485

Sources: TdgClinicalTrial ChemblInteractions TEND PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12376414

Sources: NCI

Interaction Types & Directionality: agonist (activating)

Interaction Info: Direct Interaction yes Mechanism of Interaction Adrenergic receptor agonist

PMIDs: 1346768

Sources: ChemblInteractions PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12407113

Sources: NCI

Interaction Types & Directionality: agonist (activating)

Interaction Info: Mechanism of Interaction Adrenergic receptor agonist Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info: Combination therapy Articaine,Epinephrine

PMIDs: None found

Sources: FDA

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Interaction Types & Directionality:

n/a

PMIDs:
212383

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10863002

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11239501

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
18172836

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16527847

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Novel drug target Established target

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
1980236 1979424 11053214 11728431 18064417 6134529

Sources:
TdgClinicalTrial ChemblInteractions PharmGKB

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Novel drug target Established target

PMIDs:
20857090 20412040 20954794 19730427

Sources:
TdgClinicalTrial PharmGKB

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Novel drug target Established target

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
1980236 9836297 18680204 11306720 10742288 18064417 6134529

Sources:
TdgClinicalTrial ChemblInteractions PharmGKB

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
17622774 11752352 17541557 8401205 10085337

Sources:
TdgClinicalTrial ChemblInteractions TEND PharmGKB TTD

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Adrenergic receptor agonist

Direct Interaction yes

Novel drug target Established target

PMIDs:
20857090 20412040 20954794 19730427

Sources:
TdgClinicalTrial ChemblInteractions PharmGKB

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Adrenergic receptor agonist

Direct Interaction yes

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

PMIDs:
20857090 17603545 17658513 20412040

Sources:
TdgClinicalTrial ChemblInteractions TEND PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
15210061

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name transdermal lidocaine/epinephrine patch,Lidosite

Novel drug target Established target

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
17417877 17622774 11752352 17597612 20837485

Sources:
TdgClinicalTrial ChemblInteractions TEND PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
12376414

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Adrenergic receptor agonist

PMIDs:
1346768

Sources:
ChemblInteractions PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
12407113

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Adrenergic receptor agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

Interaction Info:

Combination therapy Articaine,Epinephrine

PMIDs:
None found

Sources:
FDA

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a