DGIdb - ENOXOLONE Drug Record

ENOXOLONE chembl:CHEMBL230006

Alternate Names:

GLYCYRRHETIC ACID
NSC-35347
URALENIC ACID
RHETINIC ACID
ENOXOLONE
NSC-35350

Drug Info:

(0 More Sources)

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
Song J et al., 2014, Inhibition of protein kinase C α/βII and activation of c-Jun NH2-terminal kinase mediate glycyrrhetinic acid induced apoptosis in non-small cell lung cancer NCI-H460 cells., Bioorg Med Chem Lett
Lallemand B et al., 2011, N-(2-{3-[3,5-bis(trifluoromethyl)phenyl]ureido}ethyl)-glycyrrhetinamide (6b): a novel anticancer glycyrrhetinic acid derivative that targets the proteasome and displays anti-kinase activity., J Med Chem
Takemura M et al., 2011, Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid., J Nat Prod

ENOXOLONE AKR1B10

Interaction Score: 3.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21561086

Sources:
DTC
ENOXOLONE PRKCB

Interaction Score: 0.95

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24461294

Sources:
DTC
ENOXOLONE PRKCA

Interaction Score: 0.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24461294

Sources:
DTC
ENOXOLONE PRKCD

Interaction Score: 0.41

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24461294

Sources:
DTC
ENOXOLONE PPARG

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21888390

Sources:
DTC
ENOXOLONE CYP2C9

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
ENOXOLONE CYP2C19

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
ENOXOLONE POLK

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ENOXOLONE CYP2D6

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
ENOXOLONE CYP3A4

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC

DTC: ENOXOLONE

Version: 02-September-2020

Alternate Names:

CHEMBL230006 ChEMBL Drug ID

Drug Info:

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

Song J et al., 2014, Inhibition of protein kinase C α/βII and activation of c-Jun NH2-terminal kinase mediate glycyrrhetinic acid induced apoptosis in non-small cell lung cancer NCI-H460 cells., Bioorg Med Chem Lett

Takemura M et al., 2011, Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid., J Nat Prod

ChemblDrugs: chembl:CHEMBL230006
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

ENOXOLONE Drug Record

ENOXOLONE chembl:CHEMBL230006

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21561086

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24461294

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24461294

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24461294

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21888390

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

DTC: ENOXOLONE

Alternate Names: CHEMBL230006 ChEMBL Drug ID

Drug Info:

ChemblDrugs: chembl:CHEMBL230006

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
21561086

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
24461294

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
24461294

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
24461294

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21888390

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Alternate Names:

CHEMBL230006 ChEMBL Drug ID