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EMICIZUMAB Drug Record

  • Summary
  • Interactions
  • Claims
  • EMICIZUMAB chembl:CHEMBL3833393 Approved

    Alternate Names:

    ACE910
    EMICIZUMAB
    ACE-910
    HEMLIBRA
    chemidplus:1610943-06-0
    chembl:CHEMBL3833393
    drugbank:13923

    Drug Info:

    (0 More Sources)

    Publications:

    Shima M et al., 2016, Factor VIII-Mimetic Function of Humanized Bispecific Antibody in Hemophilia A., N Engl J Med
    Chavin SI, 1984, Factor VIII: structure and function in blood clotting., Am J Hematol
    Uchida N et al., 2016, A first-in-human phase 1 study of ACE910, a novel factor VIII-mimetic bispecific antibody, in healthy subjects., Blood
    Nogami K, 2016, Bispecific antibody mimicking factor VIII., Thromb Res
  • EMICIZUMAB   F9

    Interaction Score: 23.19

    Interaction Types & Directionality:
    antibody (inhibitory)
    cofactor (activating)

    Interaction Info:
    Mechanism of Interaction Coagulation factor IX and X other
    Direct Interaction yes

    PMIDs:
    27223146 6424437 26626991 27207420


    Sources:
    ChemblInteractions TTD

  • EMICIZUMAB   F10

    Interaction Score: 8.83

    Interaction Types & Directionality:
    activator (activating)
    antibody (inhibitory)

    Interaction Info:
    Mechanism of Interaction Coagulation factor IX and X other
    Direct Interaction yes

    PMIDs:
    27223146 6424437 26626991 27207420


    Sources:
    ChemblInteractions TTD

  • TTD: Emicizumab

    • Version: 2020.06.01

    Alternate Names:
    D09XTN TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL3833393

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL3833393

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21