• ECALLANTIDE chembl:CHEMBL1201837 Approved

    Alternate Names:

    ECALLANTIDE
    DX-88
    KALBITOR
    chembl:CHEMBL1201837
    chemidplus:460738-38-9
    drugbank:05311
    pubchem.compound:44152182
    rxcui:658708

    Drug Info:

    FDA Approval 2009
    Drug Class peptide
    Drug Indications Treatment for Hereditary Angiooedema
    Drug Class treatment for hereditary angiooedema
    Year of Approval 2009
    Drug Categories kallikreins, antagonists & inhibitors
    Drug Categories drugs used in hereditary angioedema
    Drug Type biotech
    Drug Groups investigational
    Drug Categories analgesics
    Drug Categories analgesics, non-narcotic
    Drug Categories anti-inflammatory agents
    Drug Categories antirheumatic agents
    Drug Categories central nervous system agents
    Drug Categories kallikrein inhibitors
    Drug Categories peripheral nervous system agents
    Drug Categories plasma kallikrein inhibitor
    Drug Categories sensory system agents
    (2 More Sources)
  • Interaction Score: 8.52

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    18613770


    Sources:
    DrugBank TTD

  • Interaction Score: 4.73

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 3.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    None found


  • Interaction Score: 0.79

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Plasma kallikrein inhibitor
    Direct Interaction yes

    PMIDs:
    None found