DOXEPIN Drug Record
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DOXEPIN chembl:CHEMBL1628227 Approved
Alternate Names:
SINEQUAN ZONALON P-3693A SINEPIN DOXEPIN Drug Info:
Drug Categories ethers, cyclic Drug Indications hypnotic FDA Approval approved Drug Class Small Molecule Drug Indications antimigraine agent Drug Class antidepressive agents, tricyclic Year of Approval 1969 Drug Class antipruritics Drug Groups investigational Drug Categories acid reducers Drug Categories adrenergic alpha-1 receptor antagonists Drug Categories adrenergic alpha-antagonists Drug Categories adrenergic antagonists Drug Categories agents producing tachycardia Drug Categories agents that produce hypertension Drug Categories agents that reduce seizure threshold Drug Categories anticholinergic agents Drug Categories antipruritics and local anesthetics Drug Categories antipruritics, incl. antihistamines, anesthetics, etc. Drug Categories combined inhibitors of serotonin/norepinephrine reuptake Drug Categories cytochrome p-450 cyp2d6 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp3a substrates Drug Categories cytochrome p-450 enzyme inhibitors Drug Categories cytochrome p-450 substrates Drug Categories dermatologicals Drug Categories dopamine antagonists Drug Categories drugs that are mainly renally excreted Drug Categories heterocyclic compounds, fused-ring Drug Categories histamine h1 antagonists Drug Categories histamine h2 antagonists Drug Categories hypnotics and sedatives Drug Categories muscarinic antagonists Drug Categories neurotoxic agents Drug Categories p-glycoprotein substrates Drug Categories potential qtc-prolonging agents Drug Categories qtc prolonging agents Drug Categories serotonergic drugs shown to increase risk of serotonin syndrome Drug Categories serotonin 5-ht1 receptor antagonists Drug Categories serotonin 5-ht2 receptor antagonists Drug Categories serotonin agents Drug Categories serotonin receptor antagonists Drug Categories tertiary amine tricyclic antidepressants Drug Categories tricyclics and other norepinephrine-reuptake inhibitors Publications:
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Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Novel drug target Established target Trial Name Silenor (SO-101) -
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antagonist (inhibitory) Interaction Info:
Trial Name Silenor (SO-101) Novel drug target Established target Specific Action of the Ligand Antagonist -
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inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? True -
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inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? True -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name Silenor (SO-101) Novel drug target Established target -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name Silenor (SO-101) Novel drug target Established target -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name Silenor (SO-101) Novel drug target Established target -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name Silenor (SO-101) Novel drug target Established target -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name Silenor (SO-101) Novel drug target Established target -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name Silenor (SO-101) Novel drug target Established target -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name Silenor (SO-101) Novel drug target Established target
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Alternate Names:
Doxepine-75 - Cap Drug Brand Novo-doxepin Drug Brand Ntp-doxepin Drug Brand Drug Info:
Drug Type small molecule Drug Groups approved Drug Groups investigational Publications:
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Alternate Names:
DOXEPIN Primary Drug Name Drug Info:
Drug Class antipruritics Year of Approval 1969 Drug Class antidepressive agents, tricyclic Publications:
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- Version: January-2014
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Drug Info:
Drug Indications antimigraine agent Drug Class Small Molecule FDA Approval approved Publications:
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CHEMBL1628227 ChEMBL Drug ID Drug Info:
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Drug Info:
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- Version: 29-September-2020
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DOXEPIN GuideToPharmacology Ligand Name Drug Info:
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D06FES TTD Drug ID Drug Info:
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- Version: ChEMBL_27
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Drug Info:
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Drug Info:
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