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DIPYRONE Drug Record

  • Summary
  • Interactions
  • Claims
  • DIPYRONE chembl:CHEMBL461522

    Alternate Names:

    DIPYRONE
    METAMIZOLE SODIUM MONOHYDRATE
    NSC-73205
    METAMIZOL
    SULPYRINE HYDRATE
    pubchem.compound:3111
    chemidplus:50567-35-6
    chembl:CHEMBL461522

    Drug Info:

    Drug Categories pyrazoles
    Drug Categories antipyretics
    Drug Categories aminopyrine
    Drug Groups approved
    Drug Groups investigational
    Drug Categories agents causing hyperkalemia
    Drug Categories agents that produce hypertension
    Drug Categories cytochrome p-450 cyp2b6 inducers (strength unknown)
    Drug Categories cytochrome p-450 cyp3a4 inducers
    Drug Categories cytochrome p-450 cyp3a4 inducers (strength unknown)
    Drug Categories cytochrome p-450 enzyme inducers
    Drug Categories nephrotoxic agents
    Drug Categories non cox-2 selective nsaids
    (0 More Sources)

    Publications:

    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Martínez C et al., 2014, Gender and functional CYP2C and NAT2 polymorphisms determine the metabolic profile of metamizole., Biochem Pharmacol
    García-Martín E et al., 2015, Genetic determinants of metamizole metabolism modify the risk of developing anaphylaxis., Pharmacogenet Genomics
  • DIPYRONE   NAT2

    Interaction Score: 3.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26111152 25241292


    Sources:
    PharmGKB

  • DIPYRONE   PTGS1

    Interaction Score: 0.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11752352


    Sources:
    DrugBank

  • DIPYRONE   CYP2C19

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25241292


    Sources:
    PharmGKB

  • DrugBank: DB04817

    • Version: 5.1.7

    Alternate Names:
    METAMIZOLE DrugBank Drug Name
    50567-35-6 CAS Number
    Algocalmin Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups investigational

    Publications:
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

  • PharmGKB: dipyrone

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    García-Martín E et al., 2015, Genetic determinants of metamizole metabolism modify the risk of developing anaphylaxis., Pharmacogenet Genomics
    Martínez C et al., 2014, Gender and functional CYP2C and NAT2 polymorphisms determine the metabolic profile of metamizole., Biochem Pharmacol

  • ChemblDrugs: chembl:CHEMBL461522

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21