DGIdb - DIETHYLSTILBESTROL Drug Record

DIETHYLSTILBESTROL chembl:CHEMBL411 Antineoplastic

Alternate Names:

STILBESTROFORM
ESTROGENINE
SYNESTRIN
STILBOESTROL
SYNTHESTRIN
TAMPOVAGAN
CYREN A
DIETHYLSTILBESTROL
NEW-ESTRANOL 1
PALESTROL
STILBETIN
APSTIL
ESTROMENIN
NSC-3070
ESTROBENE
STILBESTROL
STILBOESTEROL
FONATOL
DISTILBENE
TRANS-DIETHYLSTILBOESTEROL
(E)-3,4-BIS(4-HYDROXYPHENYL)-3-HEXENE
4,4'-DIHYDROXY-ALPHA,BETA-DIETHYLSTILBENE
(E)-4,4'-(1,2-DIETHYL-1,2-ETHENEDIYL)BISPHENOL
TRANS-DIETHYLSTILBESTEROL
Α,Α'-DIETHYL-(E)-4,4'-STILBENEDIOL
ALPHA,ALPHA'-DIETHYL-(E)-4,4'-STILBENEDIOL
TRANS-DIETHYLSTILBESTROL
TRANS-4,4'-(1,2-DIETHYL-1,2-ETHENEDIYL)BISPHENOL
4,4'-DIHYDROXY-Α,Β-DIETHYLSTILBENE
DES
DIETHYLSTILBESTROLUM
DIETILESTILBESTROL
chembl:CHEMBL411
chemidplus:56-53-1
pubchem.compound:448537
drugbank:00255
rxcui:3390

Drug Info:

Drug Class	hormone replacement agents
Year of Approval	approved before 1982
Drug Categories	synthetic estrogens, plain
Drug Categories	comt substrates
Drug Categories	carcinogens
Drug Categories	benzylidene compounds
FDA Approval	Approved before 1982
Drug Class	small molecule
Drug Indications	Hormone Replacement Agents
Drug Groups	investigational
Drug Categories	adrenal cortex hormones
Drug Categories	antineoplastic and immunomodulating agents
Drug Categories	bsep/abcb11 substrates
Drug Categories	contraceptive agents, female
Drug Categories	contraceptive agents, male
Drug Categories	contraceptives, postcoital
Drug Categories	cytochrome p-450 cyp2c8 inhibitors (strength unknown)
Drug Categories	cytochrome p-450 cyp2c8 substrates
Drug Categories	cytochrome p-450 cyp2c9 inhibitors (strength unknown)
Drug Categories	cytochrome p-450 cyp2e1 inhibitors (strong)
Drug Categories	cytochrome p-450 cyp3a substrates
Drug Categories	cytochrome p-450 cyp3a4 inhibitors
Drug Categories	cytochrome p-450 cyp3a4 inhibitors (strength unknown)
Drug Categories	cytochrome p-450 cyp3a4 substrates
Drug Categories	cytochrome p-450 enzyme inhibitors
Drug Categories	cytochrome p-450 substrates
Drug Categories	endocrine therapy
Drug Categories	hormonal contraceptives for systemic use
Drug Categories	hormones and related agents
Drug Categories	oatp1b1/slco1b1 inhibitors
Drug Categories	p-glycoprotein substrates
Drug Categories	thyroxine-binding globulin inducers

(7 More Sources)

Publications:

Kretschmer XC et al., 2005, CAR and PXR: xenosensors of endocrine disrupters?, Chem Biol Interact
Hodnik Ž et al., 2015, Diethylstilbestrol-scaffold-based pregnane X receptor modulators., Eur J Med Chem
Wang et al., 1990, Lectin bindings and diethylstilbestrol effects on the recognition of mullerian inhibiting substance (MIS) on chick mullerian ducts by MIS-antiserum., Histochemistry
Visser et al., 1998, Effect of prenatal exposure to diethylstilbestrol on Müllerian duct development in fetal male mice., Endocrinology
Salleh et al., 2004, Gene expression profiling of p53(+/-) knockout and wild-type mice following diethylstilbestrol administration., IUBMB Life
Nam et al., 2003, Simulation of the different biological activities of diethylstilbestrol (DES) on estrogen receptor alpha and estrogen-related receptor gamma., Biopolymers
Greschik et al., 2004, Structural basis for the deactivation of the estrogen-related receptor gamma by diethylstilbestrol or 4-hydroxytamoxifen and determinants of selectivity., J. Biol. Chem.
Tremblay et al., 2001, Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR beta., Genes Dev.
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Bains et al., 2007, Neuroprotection by estrogen against MPP+-induced dopamine neuron death is mediated by ERalpha in primary cultures of mouse mesencephalon., Exp. Neurol.
Baron et al., 2007, Estrogen receptor alpha and the activating protein-1 complex cooperate during insulin-like growth factor-I-induced transcriptional activation of the pS2/TFF1 gene., J. Biol. Chem.
Dixon et al., 2007, Renoprotective effects of a selective estrogen receptor modulator, raloxifene, in an animal model of diabetic nephropathy., Am. J. Nephrol.
Muñoz et al., Association with litter size of new polymorphisms on ESR1 and ESR2 genes in a Chinese-European pig line., Genet. Sel. Evol.
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Kwok et al., 2010, Measuring binding kinetics of ligands with tethered receptors by fluorescence polarization and total internal reflection fluorescence., Anal. Chem.
Hart et al., 2007, Estrogen mobilizes a subset of estrogen receptor-alpha-immunoreactive vesicles in inhibitory presynaptic boutons in hippocampal CA1., J. Neurosci.
Noubani et al., 2000, B-type natriuretic peptide receptor expression and activity are hormonally regulated in rat ovarian cells., Endocrinology
Miller et al., 1998, Fetal exposure to DES results in de-regulation of Wnt7a during uterine morphogenesis., Nat. Genet.
Tamura H et al., 2006, Structural basis for androgen receptor agonists and antagonists: interaction of SPEED 98-listed chemicals and related compounds with the androgen receptor based on an in vitro reporter gene assay and 3D-QSAR., Bioorg Med Chem
Ramos et al., 2007, Diethylstilbestrol alters the population dynamic of neural precursor cells in the neonatal male rat dentate gyrus., Brain Res. Bull.
Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
Wu et al., 2006, [Effect of environmental contaminants on DNA methyltransferase activity of mouse preimplantation embryos]., Wei Sheng Yan Jiu
Wang et al., 2004, Prenatal estrogen exposure differentially affects estrogen receptor-associated proteins in rat testis gonocytes., Biol. Reprod.
Shepel et al., 1990, Restriction fragment length polymorphisms in the rat N-ras and retinoblastoma genes: their identification and characterization., Oncogene
Kendall et al., 1992, The effects of diethylstilbestrol, tamoxifen, and toremifene on estrogen-inducible hepatic proteins and estrogen receptor proteins in female rats., Toxicol. Appl. Pharmacol.
2008, Final amended report on the safety assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben, and Benzylparaben as used in cosmetic products., Int. J. Toxicol.
Geistlinger et al., 2004, Ligand-selective inhibition of the interaction of steroid receptor coactivators and estrogen receptor isoforms., Chem. Biol.
Ghibaudi et al., 2000, Can estrogenic radicals, generated by lactoperoxidase, be involved in the molecular mechanism of breast carcinogenesis?, Redox Rep.
Li et al., 1983, Effect of steroid hormone treatment on aryl hydrocarbon hydroxylase activity in the Syrian hamster kidney., Biochem. Pharmacol.
Miyagawa et al., 2004, Estrogen-independent activation of erbBs signaling and estrogen receptor alpha in the mouse vagina exposed neonatally to diethylstilbestrol., Oncogene
Hong H et al., 2015, Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein., Toxicol Sci

DIETHYLSTILBESTROL WNT7A

Interaction Score: 3.44

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9806537

Sources:
NCI
DIETHYLSTILBESTROL AMH

Interaction Score: 2.58

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2286533 9751506

Sources:
NCI
DIETHYLSTILBESTROL ESRRB

Interaction Score: 2.15

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

PMIDs:
11297507 26408814

Sources:
DTC DrugBank GuideToPharmacology
DIETHYLSTILBESTROL LPO

Interaction Score: 1.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10994878

Sources:
NCI
DIETHYLSTILBESTROL ESRRG

Interaction Score: 0.93

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

PMIDs:
12579585 15161930 11297507 10592235

Sources:
NCI DrugBank GuideToPharmacology
DIETHYLSTILBESTROL PTGES3

Interaction Score: 0.57

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15229138

Sources:
NCI
DIETHYLSTILBESTROL NPPC

Interaction Score: 0.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10650935

Sources:
NCI
DIETHYLSTILBESTROL ESRRA

Interaction Score: 0.26

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11297507

Sources:
DrugBank
DIETHYLSTILBESTROL E2F1

Interaction Score: 0.22

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15545218

Sources:
NCI
DIETHYLSTILBESTROL NCOA2

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15123288

Sources:
DrugBank
DIETHYLSTILBESTROL CP

Interaction Score: 0.17

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1533964

Sources:
NCI
DIETHYLSTILBESTROL SHBG

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25349334

Sources:
DrugBank
DIETHYLSTILBESTROL DNMT1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16598927

Sources:
NCI
DIETHYLSTILBESTROL ESR1

Interaction Score: 0.1

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name -

Direct Interaction yes

PMIDs:
17320868 26408814 17317669 17308373 17306201 11752352 20387803 17314305

Sources:
TEND DTC TdgClinicalTrial TTD DrugBank GuideToPharmacology ChemblInteractions
DIETHYLSTILBESTROL HRAS

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1980008

Sources:
NCI
DIETHYLSTILBESTROL MYC

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15545218

Sources:
NCI
DIETHYLSTILBESTROL BCL2

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15545218

Sources:
NCI
DIETHYLSTILBESTROL ESR2

Interaction Score: 0.07

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? False

PMIDs:
19101832 15123288

Sources:
DrugBank GuideToPharmacology
DIETHYLSTILBESTROL SLC5A7

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIETHYLSTILBESTROL NR1I2

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16054614 26408814

Sources:
DTC PharmGKB DrugBank
DIETHYLSTILBESTROL BDNF

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17292805

Sources:
NCI
DIETHYLSTILBESTROL NR1H4

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIETHYLSTILBESTROL ERBB2

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14647453

Sources:
NCI
DIETHYLSTILBESTROL RORC

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIETHYLSTILBESTROL TP53

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15545218

Sources:
NCI
DIETHYLSTILBESTROL CYP2C9

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
DIETHYLSTILBESTROL CYP2C19

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
DIETHYLSTILBESTROL CYP1A2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
6626258

Sources:
NCI
DIETHYLSTILBESTROL CYP2D6

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
DIETHYLSTILBESTROL AR

Interaction Score: 0.01

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

PMIDs:
16876421

Sources:
DTC DrugBank
DIETHYLSTILBESTROL CYP3A4

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
DIETHYLSTILBESTROL GMNN

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIETHYLSTILBESTROL NFE2L2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

DrugBank: DB00255

Version: 5.1.7

Alternate Names:

DIETHYLSTILBESTROL DrugBank Drug Name

56-53-1 CAS Number

Distilbene Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups investigational

Publications:

Bains et al., 2007, Neuroprotection by estrogen against MPP+-induced dopamine neuron death is mediated by ERalpha in primary cultures of mouse mesencephalon., Exp. Neurol.

Baron et al., 2007, Estrogen receptor alpha and the activating protein-1 complex cooperate during insulin-like growth factor-I-induced transcriptional activation of the pS2/TFF1 gene., J. Biol. Chem.

Dixon et al., 2007, Renoprotective effects of a selective estrogen receptor modulator, raloxifene, in an animal model of diabetic nephropathy., Am. J. Nephrol.

TEND: DIETHYLSTILBESTROL
- Version: 01-August-2011
Alternate Names:

DIETHYLSTILBESTROL Primary Drug Name

Drug Info:

Year of Approval approved before 1982

Drug Class hormone replacement agents

Publications:
TdgClinicalTrial: DIETHYLSTILBESTROL
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Hormone Replacement Agents

Drug Class small molecule

FDA Approval Approved before 1982

Publications:

DTC: DIETHYLSTILBESTROL

Version: 02-September-2020

Alternate Names:

CHEMBL411 ChEMBL Drug ID

Drug Info:

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

Hodnik Ž et al., 2015, Diethylstilbestrol-scaffold-based pregnane X receptor modulators., Eur J Med Chem

NCI: DIETHYLSTILBESTROL

Version: 14-September-2017

Alternate Names:

C433 NCI drug code

Drug Info:

Publications:

Wang et al., 1990, Lectin bindings and diethylstilbestrol effects on the recognition of mullerian inhibiting substance (MIS) on chick mullerian ducts by MIS-antiserum., Histochemistry

Shepel et al., 1990, Restriction fragment length polymorphisms in the rat N-ras and retinoblastoma genes: their identification and characterization., Oncogene

Wu et al., 2006, [Effect of environmental contaminants on DNA methyltransferase activity of mouse preimplantation embryos]., Wei Sheng Yan Jiu

NCI: DES

Version: 14-September-2017

Alternate Names:

C433 NCI drug code

Drug Info:

Publications:

Salleh et al., 2004, Gene expression profiling of p53(+/-) knockout and wild-type mice following diethylstilbestrol administration., IUBMB Life

Kendall et al., 1992, The effects of diethylstilbestrol, tamoxifen, and toremifene on estrogen-inducible hepatic proteins and estrogen receptor proteins in female rats., Toxicol. Appl. Pharmacol.

Ramos et al., 2007, Diethylstilbestrol alters the population dynamic of neural precursor cells in the neonatal male rat dentate gyrus., Brain Res. Bull.

TTD: Diethylstilbestrol
- Version: 2020.06.01
Alternate Names:

D0Y2NE TTD Drug ID

Drug Info:

Publications:
GuideToPharmacology: 135651472
- Version: 29-September-2020
Alternate Names:

DIETHYLSTILBESTROL GuideToPharmacology Ligand Name

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL411
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL411
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:
PharmGKB: diethylstilbestrol
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Specific Action of the Ligand	Antagonist
Endogenous Drug?	False
Direct Interaction?	False

Novel drug target	Established target
Trial Name	-
Direct Interaction	yes

DIETHYLSTILBESTROL	DrugBank Drug Name
56-53-1	CAS Number
Distilbene	Drug Brand

Drug Type	small molecule
Drug Groups	approved
Drug Groups	investigational

agonist (activating)
antagonist (inhibitory)

DIETHYLSTILBESTROL Drug Record

DIETHYLSTILBESTROL chembl:CHEMBL411 Antineoplastic

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9806537

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 2286533 9751506

Sources: NCI

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? False Direct Interaction? False

PMIDs: 11297507 26408814

Sources: DTC DrugBank GuideToPharmacology

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10994878

Sources: NCI

Interaction Types & Directionality: agonist (activating) antagonist (inhibitory)

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? False

PMIDs: 12579585 15161930 11297507 10592235

Sources: NCI DrugBank GuideToPharmacology

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15229138

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10650935

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11297507

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15545218

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15123288

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1533964

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 25349334

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16598927

Sources: NCI

Interaction Types & Directionality: agonist (activating)

Interaction Info: Novel drug target Established target Trial Name - Direct Interaction yes

PMIDs: 17320868 26408814 17317669 17308373 17306201 11752352 20387803 17314305

Sources: TEND DTC TdgClinicalTrial TTD DrugBank GuideToPharmacology ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1980008

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15545218

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15545218

Sources: NCI

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Agonist Endogenous Drug? False

PMIDs: 19101832 15123288

Sources: DrugBank GuideToPharmacology

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Interaction Types & Directionality:

n/a

PMIDs:
9806537

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
2286533 9751506

Sources:
NCI

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

PMIDs:
11297507 26408814

Sources:
DTC DrugBank GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
10994878

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

PMIDs:
12579585 15161930 11297507 10592235

Sources:
NCI DrugBank GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
15229138

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10650935

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11297507

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
15545218

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15123288

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
1533964

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
25349334

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
16598927

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name -

Direct Interaction yes

PMIDs:
17320868 26408814 17317669 17308373 17306201 11752352 20387803 17314305

Sources:
TEND DTC TdgClinicalTrial TTD DrugBank GuideToPharmacology ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
1980008

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15545218

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15545218

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? False

PMIDs:
19101832 15123288

Sources:
DrugBank GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
16054614 26408814

Sources:
DTC PharmGKB DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
17292805

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
14647453

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
15545218

Sources:
NCI

Interaction Types & Directionality:

n/a