GLOPERBA |
COLCHICINE |
MITIGARE |
NSC-757 |
COLCRYS |
BENZO(A)HEPTALEN-9(5H)-ONE |
COLCHICINA |
CONDYLON |
N-(1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDROBENZO[A]HEPTALEN-7-YL)ACETAMIDE |
COLSALOID |
COLCHICIN |
COLCHICINUM |
(S)-N-(5,6,7,9-TETRAHYDRO-1,2,3,10-TETRAMETHOXY-9-OXOBENZO[A]HEPTALEN-7-YL)ACETAMIDE |
COLGOUT |
N-(5,6,7,9-TETRAHYDRO-1,2,3,10-TETRAMETHOXY-9-OXOBENZO[A]HEPTALEN-7-YL)ACETAMIDE |
N-ACETYLTRIMETHYLCOLCHICINIC ACID METHYL ETHER |
drugbank:01394 |
chembl:CHEMBL87 |
chemidplus:64-86-8 |
rxcui:2683 |
pubchem.compound:6167 |
chembl:CHEMBL107 |
FDA Approval | approved |
Drug Class | Small Molecule |
Drug Indications | for treatment of gout |
Drug Class | gout suppressants |
Year of Approval | approved before 1982 |
Drug Categories | preparations with no effect on uric acid metabolism |
Drug Categories | antigout preparations |
Drug Categories | agents causing muscle toxicity |
Drug Categories | cytochrome p-450 cyp2b6 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp2c8 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp2e1 inducers (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a4 inducers |
Drug Categories | cytochrome p-450 cyp3a4 inducers (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 enzyme inducers |
Drug Categories | cytochrome p-450 enzyme inhibitors |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | drugs that are mainly renally excreted |
Drug Categories | immunosuppressive agents |
Drug Categories | p-glycoprotein inducers |
Drug Categories | p-glycoprotein substrates |
binder |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | colchicine,Colcrys |
Mechanism of Interaction | Tubulin inhibitor |
antagonist (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Antagonist |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Direct Interaction? | False |
64-86-8 | CAS Number |
Colchicine Tab 0.6mg | Drug Brand |
Colchicine Tab 1mg | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Categories | agents causing muscle toxicity |
Year of Approval | approved before 1982 |
Drug Class | gout suppressants |
Drug Indications | for treatment of gout |
Drug Class | Small Molecule |
FDA Approval | approved |
CHEMBL107 | ChEMBL Drug ID |
C385 | NCI drug code |
D09DHY | TTD Drug ID |