CLOZAPINE RESOLUTION MIXTURE |
HF-1854 |
CLOZARIL |
FAZACLO |
VERSACLOZ |
ZAPONEX |
CLOZAPINE |
FAZACLO ODT |
CLOZAPIN |
CLOZAPINUM |
CLORAZIL® |
LEX123 |
CLOZAPINA |
rxcui:2626 |
drugbank:00363 |
chembl:CHEMBL42 |
chemidplus:5786-21-0 |
pubchem.compound:2818 |
Drug Categories | gaba antagonists |
FDA Approval | 1989 |
Drug Class | small molecule |
Drug Indications | Antipsychotic Agents |
Drug Class | antipsychotic agents |
Year of Approval | 1989 |
Drug Categories | adrenergic alpha-1 receptor antagonists |
Drug Categories | adrenergic alpha-antagonists |
Drug Categories | adrenergic antagonists |
Drug Categories | agents producing tachycardia |
Drug Categories | agents that produce hypertension |
Drug Categories | agents that reduce seizure threshold |
Drug Categories | anticholinergic agents |
Drug Categories | antidepressive agents |
Drug Categories | cytochrome p-450 cyp1a2 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp2c19 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp2c19 inhibitors (weak) |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a4 inducers |
Drug Categories | cytochrome p-450 cyp3a4 inducers (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors (moderate) |
Drug Categories | cytochrome p-450 cyp3a4 substrates with a narrow therapeutic index |
Drug Categories | cytochrome p-450 enzyme inducers |
Drug Categories | cytochrome p-450 enzyme inhibitors |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | dopamine antagonists |
Drug Categories | dopamine d2 receptor antagonists |
Drug Categories | drugs causing inadvertant photosensitivity |
Drug Categories | drugs that are mainly renally excreted |
Drug Categories | heterocyclic compounds, fused-ring |
Drug Categories | histamine antagonists |
Drug Categories | histamine h1 antagonists |
Drug Categories | muscarinic antagonists |
Drug Categories | neurotoxic agents |
Drug Categories | p-glycoprotein substrates |
Drug Categories | photosensitizing agents |
Drug Categories | qtc prolonging agents |
Drug Categories | serotonin 5-ht2 receptor antagonists |
Drug Categories | serotonin receptor antagonists |
Drug Categories | ugt1a4 substrates |
antagonist (inhibitory) |
Endogenous Drug? | False |
Specific Action of the Ligand | Antagonist |
Trial Name | - |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
Specific Action of the Ligand | Antagonist |
antagonist (inhibitory) |
Endogenous Drug? | False |
Specific Action of the Ligand | Antagonist |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Specific Action of the Ligand | Inverse agonist |
agonist (activating) |
antagonist (inhibitory) |
Endogenous Drug? | False |
Specific Action of the Ligand | Full agonist |
antagonist (inhibitory) |
Specific Action of the Ligand | Inverse agonist |
Endogenous Drug? | False |
Direct Interaction? | True |
agonist (activating) |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Specific Action of the Ligand | Full agonist |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Inverse agonist |
Endogenous Drug? | False |
agonist (activating) |
antagonist (inhibitory) |
Specific Action of the Ligand | Full agonist |
Endogenous Drug? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Trial Name | - |
agonist (activating) |
antagonist (inhibitory) |
Specific Action of the Ligand | Full agonist |
Endogenous Drug? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Trial Name | - |
agonist (activating) |
Specific Action of the Ligand | Full agonist |
Endogenous Drug? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
allosteric modulator |
antagonist (inhibitory) |
Specific Action of the Ligand | Positive |
Endogenous Drug? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
CLOZAPINE | DrugBank Drug Name |
5786-21-0 | CAS Number |
Aa-clozapine | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Categories | adrenergic alpha-1 receptor antagonists |
CLOZAPINE | Primary Drug Name |
Year of Approval | 1989 |
Drug Class | antipsychotic agents |
Drug Indications | Antipsychotic Agents |
Drug Class | small molecule |
FDA Approval | 1989 |
C28936 | NCI drug code |
CHEMBL42 | ChEMBL Drug ID |
D0Z1RV | TTD Drug ID |
CLOZAPINE | GuideToPharmacology Ligand Name |