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CLAVULANIC ACID Drug Record

  • Summary
  • Interactions
  • Claims
  • CLAVULANIC ACID chembl:CHEMBL777 Approved

    Alternate Names:

    RX-10100
    CLAVULANATE
    BRL-14151
    CLAVULANIC ACID
    CLAVULANSAEURE
    (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
    ANTIBIOTIC MM 14151
    ACIDE CLAVULANIQUE
    (Z)-(2R,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID
    ACIDUM CLAVULANICUM
    MM 14151
    ÁCIDO CLAVULÁNICO
    CLAVULONIC ACID
    ACIDO CLAVULANICO
    CLAVULANSÄURE
    rxcui:21216
    chemidplus:58001-44-8
    chembl:CHEMBL777
    drugbank:00766
    pubchem.compound:5280980
    rxcui:48203

    Drug Info:

    (0 More Sources)

    Publications:

    Cirulli ET et al., 2019, A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury., Gastroenterology
    Donaldson PT et al., 2010, Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury., J Hepatol
    Hautekeete ML et al., 1999, HLA association of amoxicillin-clavulanate--induced hepatitis., Gastroenterology
  • CLAVULANIC ACID   HLA-DRB5

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10535882


    Sources:
    PharmGKB

  • CLAVULANIC ACID   HLA-DRA

    Interaction Score: 2.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875


    Sources:
    PharmGKB

  • CLAVULANIC ACID   HLA-DQB1

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875 10535882


    Sources:
    PharmGKB

  • CLAVULANIC ACID   HLA-C

    Interaction Score: 1.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875


    Sources:
    PharmGKB

  • CLAVULANIC ACID   HLA-DRB1

    Interaction Score: 1.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875 20800921 10535882


    Sources:
    PharmGKB

  • CLAVULANIC ACID   HLA-B

    Interaction Score: 0.71

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875


    Sources:
    PharmGKB

  • CLAVULANIC ACID   HLA-A

    Interaction Score: 0.59

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • PharmGKB: clavulanate

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Cirulli ET et al., 2019, A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury., Gastroenterology
    Hautekeete ML et al., 1999, HLA association of amoxicillin-clavulanate--induced hepatitis., Gastroenterology
    Donaldson PT et al., 2010, Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury., J Hepatol

  • TTD: Clavulanate

    • Version: 2020.06.01

    Alternate Names:
    D0X7JN TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL777

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21