DGIdb - CINNARIZINE Drug Record

CINNARIZINE chembl:CHEMBL43064 Approved

Alternate Names:

516 MD
R-516
STUNARONE
STUGERON FTE
STUGERON
R-1575
MARZINE R.F.
STUTGIN
516-MD
MYLAN TRAVEL SICKNESS
CINNARIZINE
1-CINNAMYL-4-(DIPHENYLMETHYL)PIPERAZINE
1-BENZHYDRYL-4-CINNAMYLPIPERAZIN
CINNARIZINUM
STUGERON®
1-(DIPHENYLMETHYL)-4-(3-PHENYL-2-PROPENYL)PIPERAZINE
CINARIZINA
chembl:CHEMBL43064
drugbank:00568
chemidplus:298-57-7
rxcui:2549
pubchem.compound:1547484

Drug Info:

FDA Approval	not approved by the FDA
Drug Class	small molecule
Drug Indications	Anti-Allergic Agents
Year of Approval	not approved by the fda
Drug Class	anti-allergic agents

(1 More Sources)

Publications:

Paton et al., Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines)., Clin Pharmacokinet
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol

CINNARIZINE CFL1

Interaction Score: 2.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16680159

Sources:
DTC
CINNARIZINE JUN

Interaction Score: 0.4

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16680159

Sources:
DTC
CINNARIZINE CDK1

Interaction Score: 0.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16680159

Sources:
DTC
CINNARIZINE HRH1

Interaction Score: 0.35

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
2866055 11752352

Sources:
TdgClinicalTrial TEND TTD
CINNARIZINE NPSR1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CINNARIZINE TP53

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16680159

Sources:
DTC
CINNARIZINE KCNH2

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

TEND: CINNARIZINE
- Version: 01-August-2011
Alternate Names:

CINNARIZINE Primary Drug Name

Drug Info:

Drug Class anti-allergic agents

Year of Approval not approved by the fda

Publications:
TdgClinicalTrial: CINNARIZINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Anti-Allergic Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Publications:
DTC: CINNARIZINE
- Version: 02-September-2020
Alternate Names:

CHEMBL43064 ChEMBL Drug ID

Drug Info:

Publications:

MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol
TTD: Cinnarizine
- Version: 2020.06.01
Alternate Names:

D0Q3YO TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL43064
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Novel drug target	Established target
Trial Name	-

CINNARIZINE Drug Record

CINNARIZINE chembl:CHEMBL43064 Approved

Alternate Names:

Drug Info:

Publications:

CINNARIZINE CFL1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16680159

Sources: DTC

CINNARIZINE JUN

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16680159

Sources: DTC

CINNARIZINE CDK1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16680159

Sources: DTC

CINNARIZINE HRH1

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Novel drug target Established target Trial Name -

PMIDs: 2866055 11752352

Sources: TdgClinicalTrial TEND TTD

CINNARIZINE NPSR1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

CINNARIZINE TP53

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16680159

Sources: DTC

CINNARIZINE KCNH2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

TEND: CINNARIZINE

Alternate Names: CINNARIZINE Primary Drug Name

Drug Info: Drug Class anti-allergic agents Year of Approval not approved by the fda

Publications:

TdgClinicalTrial: CINNARIZINE

Alternate Names:

Drug Info: Drug Indications Anti-Allergic Agents Drug Class small molecule FDA Approval not approved by the FDA

Publications:

DTC: CINNARIZINE

Alternate Names: CHEMBL43064 ChEMBL Drug ID

Drug Info:

Publications: MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol

TTD: Cinnarizine

Alternate Names: D0Q3YO TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL43064

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
16680159

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
16680159

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
16680159

Sources:
DTC

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
2866055 11752352

Sources:
TdgClinicalTrial TEND TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
16680159

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

CINNARIZINE Primary Drug Name

Drug Info:

Drug Class anti-allergic agents

Year of Approval not approved by the fda

Drug Info:

Drug Indications Anti-Allergic Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Alternate Names:

CHEMBL43064 ChEMBL Drug ID

Publications:

MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol

Alternate Names:

D0Q3YO TTD Drug ID