DGIdb - CHEMBL285063 Drug Record

CHEMBL285063 chembl:CHEMBL285063

Alternate Names:

PD-168393

Drug Info:

(0 More Sources)

Publications:

Hur W et al., 2008, Clinical stage EGFR inhibitors irreversibly alkylate Bmx kinase., Bioorg Med Chem Lett
Blair JA et al., 2007, Structure-guided development of affinity probes for tyrosine kinases using chemical genetics., Nat Chem Biol
Vacondio F et al., 2013, Long-lasting inhibition of EGFR autophosphorylation in A549 tumor cells by intracellular accumulation of non-covalent inhibitors., Bioorg Med Chem Lett
Smaill JB et al., 1999, Tyrosine kinase inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(phenylamino)pyrido[d]pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor., J Med Chem
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

CHEMBL285063 BMX

Interaction Score: 20.61

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18667312

Sources:
DTC
CHEMBL285063 EGFR

Interaction Score: 0.92

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17334377 23988354 10346932 10592235

Sources:
DTC

DTC: PD-168393

Version: 02-September-2020

Alternate Names:

CHEMBL285063 ChEMBL Drug ID

Drug Info:

Publications:

Blair JA et al., 2007, Structure-guided development of affinity probes for tyrosine kinases using chemical genetics., Nat Chem Biol

Vacondio F et al., 2013, Long-lasting inhibition of EGFR autophosphorylation in A549 tumor cells by intracellular accumulation of non-covalent inhibitors., Bioorg Med Chem Lett

Smaill JB et al., 1999, Tyrosine kinase inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(phenylamino)pyrido[d]pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor., J Med Chem

ChemblDrugs: chembl:CHEMBL285063
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications: