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CELECOXIB Drug Record

  • Summary
  • Interactions
  • Claims
  • CELECOXIB chembl:CHEMBL118 Antineoplastic

    Alternate Names:

    DFN-15
    ONSENAL
    CELEBRA
    CELEBREX
    CELECOXIB
    DFN15
    SC-58635
    CELECOX®
    CELECOXIBUM
    CELOCOXIB
    4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENE-1-SULFONAMIDE
    CÉLÉCOXIB
    4-[5-(4-METHYLPHENYL)-3-TRIFLUOROMETHYL)-1H-PYRAZOL-YL]BENZENESULFONAMIDE
    ONSENAL®
    P-(5-P-TOLYL-3-(TRIFLUOROMETHYL)PYRAZOL-1-YL)BENZENESULFONAMIDE
    drugbank:00482
    pubchem.compound:2662
    chemidplus:169590-42-5
    rxcui:140587
    chembl:CHEMBL118

    Drug Info:

    FDA Approval approved
    Drug Class Small molecule
    Drug Indications NSAID
    (8 More Sources)

    Publications:

    Kraus S et al., 2013, Impact of genetic polymorphisms on adenoma recurrence and toxicity in a COX2 inhibitor (celecoxib) trial: results from a pilot study., Pharmacogenet Genomics
    Zhu et al., 2004, From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors., Cancer Res.
    Kulp et al., 2004, 3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells., Cancer Res.
    Li et al., 2006, A structurally optimized celecoxib derivative inhibits human pancreatic cancer cell growth., J. Gastrointest. Surg.
    Tseng et al., 2006, Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor., Mol. Pharmacol.
    Tong et al., 2005, Neutrophil gelatinase-associated lipocalin as a survival factor., Biochem. J.
    Arico et al., 2002, Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line., J. Biol. Chem.
    Gong L et al., 2012, Celecoxib pathways: pharmacokinetics and pharmacodynamics., Pharmacogenet Genomics
    Li H et al., 2011, Fragment-based drug design and drug repositioning using multiple ligand simultaneous docking (MLSD): identifying celecoxib and template compounds as novel inhibitors of signal transducer and activator of transcription 3 (STAT3)., J Med Chem
    Lu et al., 2002, Cyclooxygenase-2 inhibitor celecoxib inhibits promotion of mammary tumorigenesis in rats fed a high fat diet rich in n-6 polyunsaturated fatty acids., Cancer Lett.
    Sigthorsson et al., 2002, COX-1 and 2, intestinal integrity, and pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in mice., Gastroenterology
    Scheiman, 2002, Outcomes studies of the gastrointestinal safety of cyclooxygenase-2 inhibitors., Cleve Clin J Med
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Reddy et al., 2002, Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors., J. Environ. Pathol. Toxicol. Oncol.
    Ahmad et al., 2002, Renal failure associated with the use of celecoxib and rofecoxib., Drug Saf
    Grosser T, 2009, Variability in the response to cyclooxygenase inhibitors: toward the individualization of nonsteroidal anti-inflammatory drug therapy., J Investig Med
    Namba et al., 2007, Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells., Mol. Pharmacol.
    Kim et al., 2007, GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells., Carcinogenesis
    Kim et al., 2006, GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells., Carcinogenesis
    Tsutsumi et al., 2004, Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis., Cell Death Differ.
    Fabricio et al., 2005, The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats., Am. J. Physiol. Regul. Integr. Comp. Physiol.
    Buchanan et al., 2007, Targeting cyclooxygenase-2 and the epidermal growth factor receptor for the prevention and treatment of intestinal cancer., Cancer Res.
    Kim SH et al., 2017, Effects of CYP2C9 genetic polymorphisms on the pharmacokinetics of celecoxib and its carboxylic acid metabolite., Arch Pharm Res
    Liu R et al., 2015, Influence of genetic polymorphisms on the pharmacokinetics of celecoxib and its two main metabolites in healthy Chinese subjects., Eur J Pharm Sci
    Gupta A et al., 2015, Novel Use of Pharmacogenetic Testing in the Identification of CYP2C9 Polymorphisms Related to NSAID-Induced Gastropathy., Pain Med
    Prieto-Pérez R et al., 2013, Evaluation of the relationship between polymorphisms in CYP2C8 and CYP2C9 and the pharmacokinetics of celecoxib., J Clin Pharmacol
    Pilotto A et al., 2007, Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms., Gastroenterology
    Fries S et al., 2006, Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2., Gastroenterology
    Stempak D et al., 2005, Cytochrome P450 2C9 genotype: impact on celecoxib safety and pharmacokinetics in a pediatric patient., Clin Pharmacol Ther
    Kirchheiner J et al., 2003, Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites., Pharmacogenetics
    Tang C et al., 2001, In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelic variant forms of human liver microsomal cytochrome P450 2C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics., Pharmacogenetics
    Koeberle A et al., 2009, Discovery of benzo[g]indol-3-carboxylates as potent inhibitors of microsomal prostaglandin E(2) synthase-1., Bioorg Med Chem
    Hanke T et al., 2013, Synthesis and pharmacological characterization of benzenesulfonamides as dual species inhibitors of human and murine mPGES-1., Bioorg Med Chem
    Koeberle A et al., 2008, Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase., J Med Chem
    Sibilia et al., 2008, Central ghrelin gastroprotection involves nitric oxide/prostaglandin cross-talk., Br. J. Pharmacol.
    Zanger UM et al., 2008, Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation., Anal Bioanal Chem
    Ma et al., 2002, Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance., Proc. Natl. Acad. Sci. U.S.A.
    McKew JC et al., 2008, Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib., J Med Chem
    Vardar-Sengül et al., 2006, Effects of selective cyclooxygenase-2 inhibitor and omega-3 fatty acid on serum interleukin-1beta, osteocalcin, and C-reactive protein levels in rats., J. Periodontol.
    Narayanan et al., 2006, Docosahexaenoic acid in combination with celecoxib modulates HSP70 and p53 proteins in prostate cancer cells., Int. J. Cancer
    Haupt et al., 2006, Celecoxib can induce cell death independently of cyclooxygenase-2, p53, Mdm2, c-Abl and reactive oxygen species., Anticancer Drugs
    Andrews et al., 2005, Celecoxib inhibits urokinase-type plasminogen activator (uPA) production in MDA-MB-231 breast cancer cells., Breast Cancer Res. Treat.
    Hedberg ML et al., 2019, Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for <i>PIK3CA</i>-altered head and neck cancer., J Exp Med
  • CELECOXIB   MT-CO2

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18498150


    Sources:
    DTC

  • CELECOXIB   BCAR1

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   IL23R

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23778325


    Sources:
    PharmGKB

  • CELECOXIB   ATP2A3

    Interaction Score: 1.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   PTGES

    Interaction Score: 0.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23778325 19884011 24183739 19053751


    Sources:
    DTC PharmGKB

  • CELECOXIB   IGFBP3

    Interaction Score: 0.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   ATP2A2

    Interaction Score: 0.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   PTGER4

    Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23778325


    Sources:
    PharmGKB

  • CELECOXIB   CASP9

    Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   PDK1

    Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   PDPK1

    Interaction Score: 0.33

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    15205346 14973075 16455452 16887935 16060857 12000750


    Sources:
    NCI

  • CELECOXIB   KCNQ2

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNA2D4

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   KCNQ4

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNA2D3

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   DDIT3

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17167033 17166886 16597647 15131590 22336956


    Sources:
    NCI PharmGKB

  • CELECOXIB   CACNA1E

    Interaction Score: 0.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   KCNQ3

    Interaction Score: 0.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   KCNQ5

    Interaction Score: 0.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   COL18A1

    Interaction Score: 0.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12232050


    Sources:
    NCI

  • CELECOXIB   CACNB4

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNB3

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNB1

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   ATP2A1

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNA2D2

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNB2

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNA1A

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CA9

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   PTGS2

    Interaction Score: 0.17

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes
    Novel drug target Established target
    Trial Name celecoxib,Celebrex, Celecox

    PMIDs:
    12104042 12055598 12086292 11752352 12086402 12093311 22336956 19602986


    Sources:
    TALC TdgClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial PharmGKB TTD

  • CELECOXIB   CDKN1B

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   GHRL

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18414388


    Sources:
    NCI

  • CELECOXIB   EDN1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15539607


    Sources:
    NCI

  • CELECOXIB   MMP9

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CA12

    Interaction Score: 0.16

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   KCNQ1

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNA1I

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CTNNB1

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNA1G

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CDKN1A

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNA2D1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   APC

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    17909047


    Sources:
    JAX-CKB

  • CELECOXIB   ALOX12

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23778325


    Sources:
    PharmGKB

  • CELECOXIB   BGLAP

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16584347


    Sources:
    NCI

  • CELECOXIB   CACNA1F

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   STAT3

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21678971


    Sources:
    DTC

  • CELECOXIB   CACNA1D

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   PLAU

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16172791


    Sources:
    NCI

  • CELECOXIB   CACNA1H

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNA1B

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   HSPA4

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16646082


    Sources:
    NCI

  • CELECOXIB   CACNA1S

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CACNA1C

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   CASP3

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   VEGFA

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   ABL1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16917206


    Sources:
    NCI

  • CELECOXIB   CYP2C9

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27864660 26360837 25585969 23996211 22336956 17681167 16401468 16153401 12893985 11337938


    Sources:
    PharmGKB FDA

  • CELECOXIB   CYP3A5

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18695978


    Sources:
    PharmGKB

  • CELECOXIB   PPARG

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • CELECOXIB   PIK3CA

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30683736


    Sources:
    CIViC

  • CELECOXIB   RORC

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CELECOXIB   CYP3A4

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    DTC PharmGKB

  • CELECOXIB   NFE2L2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CELECOXIB   AR

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TdgClinicalTrial: CELECOXIB

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications NSAID
    Drug Class Small molecule
    FDA Approval approved

    Publications:

  • NCI: CELECOXIB

    • Version: 14-September-2017

    Alternate Names:
    C1728 NCI drug code

    Drug Info:

    Publications:
    Fabricio et al., 2005, The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats., Am. J. Physiol. Regul. Integr. Comp. Physiol.
    Haupt et al., 2006, Celecoxib can induce cell death independently of cyclooxygenase-2, p53, Mdm2, c-Abl and reactive oxygen species., Anticancer Drugs
    Namba et al., 2007, Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells., Mol. Pharmacol.

  • DTC: CELECOXIB

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL118 ChEMBL Drug ID

    Drug Info:

    Publications:
    McKew JC et al., 2008, Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib., J Med Chem
    Li H et al., 2011, Fragment-based drug design and drug repositioning using multiple ligand simultaneous docking (MLSD): identifying celecoxib and template compounds as novel inhibitors of signal transducer and activator of transcription 3 (STAT3)., J Med Chem
    Koeberle A et al., 2009, Discovery of benzo[g]indol-3-carboxylates as potent inhibitors of microsomal prostaglandin E(2) synthase-1., Bioorg Med Chem

  • JAX-CKB: Celecoxib

    • Version: 27-September-2017

    Alternate Names:

    Drug Info:

    Publications:
    Buchanan et al., 2007, Targeting cyclooxygenase-2 and the epidermal growth factor receptor for the prevention and treatment of intestinal cancer., Cancer Res.

  • PharmGKB: celecoxib

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Kraus S et al., 2013, Impact of genetic polymorphisms on adenoma recurrence and toxicity in a COX2 inhibitor (celecoxib) trial: results from a pilot study., Pharmacogenet Genomics
    Gong L et al., 2012, Celecoxib pathways: pharmacokinetics and pharmacodynamics., Pharmacogenet Genomics
    Kirchheiner J et al., 2003, Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites., Pharmacogenetics

  • CIViC: CELECOXIB

    • Version: 14-September-2020

    Alternate Names:

    Drug Info:

    Publications:
    Hedberg ML et al., 2019, Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for <i>PIK3CA</i>-altered head and neck cancer., J Exp Med

  • TALC: CELECOXIB

    • Version: 12-May-2016

    Alternate Names:
    CELECOXIB Primary Drug Name
    CELECOXIB Drug Generic Name
    CELEBREX Drug Trade Name

    Drug Info:

    Publications:

  • TTD: Celecoxib

    • Version: 2020.06.01

    Alternate Names:
    D03RTS TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL118

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • MyCancerGenomeClinicalTrial: CELECOXIB

    • Version: 30-February-2014

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL118

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

  • FDA: Celecoxib

    • Version: 04-September-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21