DGIdb - CARBETOCIN Drug Record

CARBETOCIN chembl:CHEMBL3301668 Approved

Alternate Names:

CARBETOCIN
PABAL
LV-101
CARBETOCINUM
1-BUTYRIC ACID-2-(3-(P-METHOXYPHENYL)-L-ALANINE)OXYTOCIN
1-BUTANOIC ACID-2-(O-METHYL-L-TYROSINE)-1-CARBAOXYTOCIN
DEAMINO-2-O-METHYLTYROSINE-1-CARBAOXYTOCIN
CARBETOCINO
pubchem.compound:16681432
drugbank:01282
chembl:CHEMBL3301668
chemidplus:37025-55-1

Drug Info:

Drug Class	labor inducing agents
Year of Approval	not approved by the fda
FDA Approval	not approved by the FDA
Drug Class	small molecule
Drug Indications	Labor Inducing Agents

(1 More Sources)

Publications:

Gimpl et al., 2005, Binding domains of the oxytocin receptor for the selective oxytocin receptor antagonist barusiban in comparison to the agonists oxytocin and carbetocin., Eur. J. Pharmacol.
Engstrøm et al., 1998, Oxytocin receptor binding and uterotonic activity of carbetocin and its metabolites following enzymatic degradation., Eur. J. Pharmacol.
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Wiśniewski K et al., 2014, New, potent, and selective peptidic oxytocin receptor agonists., J Med Chem

CARBETOCIN OXTR

Interaction Score: 14.27

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
15740719 9760035 11752352

Sources:
TdgClinicalTrial TEND TTD
CARBETOCIN AVPR1A

Interaction Score: 3.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24874785

Sources:
DTC

TEND: CARBETOCIN
- Version: 01-August-2011
Alternate Names:

CARBETOCIN Primary Drug Name

Drug Info:

Year of Approval not approved by the fda

Drug Class labor inducing agents

Publications:
TdgClinicalTrial: CARBETOCIN
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Labor Inducing Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Publications:
DTC: CARBETOCIN
- Version: 02-September-2020
Alternate Names:

CHEMBL3301668 ChEMBL Drug ID

Drug Info:

Publications:

Wiśniewski K et al., 2014, New, potent, and selective peptidic oxytocin receptor agonists., J Med Chem
TTD: Carbetocin
- Version: 2020.06.01
Alternate Names:

D08FJL TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL3301668
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target

CARBETOCIN Drug Record

CARBETOCIN chembl:CHEMBL3301668 Approved

Alternate Names:

Drug Info:

Publications:

CARBETOCIN OXTR

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 15740719 9760035 11752352

Sources: TdgClinicalTrial TEND TTD

CARBETOCIN AVPR1A

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24874785

Sources: DTC

TEND: CARBETOCIN

Alternate Names: CARBETOCIN Primary Drug Name

Drug Info: Year of Approval not approved by the fda Drug Class labor inducing agents

Publications:

TdgClinicalTrial: CARBETOCIN

Alternate Names:

Drug Info: Drug Indications Labor Inducing Agents Drug Class small molecule FDA Approval not approved by the FDA

Publications:

DTC: CARBETOCIN

Alternate Names: CHEMBL3301668 ChEMBL Drug ID

Drug Info:

Publications: Wiśniewski K et al., 2014, New, potent, and selective peptidic oxytocin receptor agonists., J Med Chem

TTD: Carbetocin

Alternate Names: D08FJL TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL3301668

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
15740719 9760035 11752352

Sources:
TdgClinicalTrial TEND TTD

Interaction Types & Directionality:

n/a

PMIDs:
24874785

Sources:
DTC

Alternate Names:

CARBETOCIN Primary Drug Name

Drug Info:

Year of Approval not approved by the fda

Drug Class labor inducing agents

Drug Info:

Drug Indications Labor Inducing Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Alternate Names:

CHEMBL3301668 ChEMBL Drug ID

Publications:

Wiśniewski K et al., 2014, New, potent, and selective peptidic oxytocin receptor agonists., J Med Chem

Alternate Names:

D08FJL TTD Drug ID