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CALCITONIN Drug Record

  • Summary
  • Interactions
  • Claims
  • CALCITONIN chembl:CHEMBL3989767 Approved

    Alternate Names:

    CALCITARE
    CALCITONIN
    CIBACALCIN
    MIACALCIC
    CALSYNAR
    FORTICAL
    FORCALTONIN
    CALCIMAR

    Drug Info:

    Drug Class Small molecule
    Drug Indications antiosteoporotic agent
    FDA Approval approved
    (0 More Sources)

    Publications:

    Thomas et al., 2005, Calcitonin induces apoptosis resistance in prostate cancer cell lines against cytotoxic drugs via the Akt/survivin pathway., Cancer Biol. Ther.
    Deftos et al., 1982, Changes in plasma bone GLA protein during treatment of bone disease., Calcif. Tissue Int.
    Yaoi et al., 2003, Expression and localization of prohormone convertase PC1 in the calcitonin-producing cells of the bullfrog ultimobranchial gland., J. Histochem. Cytochem.
    Hansen et al., 1979, Small cell carcinoma of the lung: relation of calcitonin to bone marrow metastases, parathormone and gastrin., Acta Med Scand
    Kaji et al., 1994, Calcitonin inhibits osteopontin mRNA expression in isolated rabbit osteoclasts., Endocrinology
  • CALCITONIN   PCSK1

    Interaction Score: 9.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14566018


    Sources:
    NCI

  • CALCITONIN   SPP1

    Interaction Score: 3.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8013390


    Sources:
    NCI

  • CALCITONIN   CALCR

    Interaction Score: 2.1

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Trial Name BN-002,Capsitonin
    Novel drug target Established target
    Trial Name ViaDerm-Calcitonin

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial GuideToPharmacology

  • CALCITONIN   PTH

    Interaction Score: 1.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    227233


    Sources:
    NCI

  • CALCITONIN   BGLAP

    Interaction Score: 0.7

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6805917


    Sources:
    NCI

  • CALCITONIN   BIRC5

    Interaction Score: 0.5

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16222118


    Sources:
    NCI

  • GuideToPharmacology: 135651700

    • Version: 29-September-2020

    Alternate Names:
    CALCA Gene Symbol (for Endogenous Peptides)
    CALCITONIN GuideToPharmacology Ligand Name

    Drug Info:
    Name of the Ligand Species (if a Peptide) Human

    Publications:

  • TdgClinicalTrial: CALCITONIN

    • Version: January-2014

    Alternate Names:

    Drug Info:
    FDA Approval approved
    Drug Indications antiosteoporotic agent
    Drug Class Small molecule

    Publications:

  • NCI: CALCITONIN

    • Version: 14-September-2017

    Alternate Names:
    C329 NCI drug code

    Drug Info:

    Publications:
    Thomas et al., 2005, Calcitonin induces apoptosis resistance in prostate cancer cell lines against cytotoxic drugs via the Akt/survivin pathway., Cancer Biol. Ther.
    Deftos et al., 1982, Changes in plasma bone GLA protein during treatment of bone disease., Calcif. Tissue Int.
    Yaoi et al., 2003, Expression and localization of prohormone convertase PC1 in the calcitonin-producing cells of the bullfrog ultimobranchial gland., J. Histochem. Cytochem.

  • ChemblDrugs: chembl:CHEMBL3989767

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21