DGIdb - CALCITONIN Drug Record

CALCITONIN chembl:CHEMBL3989767 Approved

Alternate Names:

CALCITARE
CALCITONIN
CIBACALCIN
MIACALCIC
CALSYNAR
FORTICAL
FORCALTONIN
CALCIMAR

Drug Info:

Drug Class	Small molecule
Drug Indications	antiosteoporotic agent
FDA Approval	approved

(0 More Sources)

Publications:

Thomas et al., 2005, Calcitonin induces apoptosis resistance in prostate cancer cell lines against cytotoxic drugs via the Akt/survivin pathway., Cancer Biol. Ther.
Deftos et al., 1982, Changes in plasma bone GLA protein during treatment of bone disease., Calcif. Tissue Int.
Yaoi et al., 2003, Expression and localization of prohormone convertase PC1 in the calcitonin-producing cells of the bullfrog ultimobranchial gland., J. Histochem. Cytochem.
Hansen et al., 1979, Small cell carcinoma of the lung: relation of calcitonin to bone marrow metastases, parathormone and gastrin., Acta Med Scand
Kaji et al., 1994, Calcitonin inhibits osteopontin mRNA expression in isolated rabbit osteoclasts., Endocrinology

CALCITONIN PCSK1

Interaction Score: 10.63

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14566018

Sources:
NCI
CALCITONIN SPP1

Interaction Score: 3.54

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8013390

Sources:
NCI
CALCITONIN CALCR

Interaction Score: 2.36

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name BN-002,Capsitonin

Novel drug target Established target

Trial Name ViaDerm-Calcitonin

PMIDs:
None found

Sources:
TdgClinicalTrial GuideToPharmacology
CALCITONIN PTH

Interaction Score: 1.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
227233

Sources:
NCI
CALCITONIN BGLAP

Interaction Score: 0.92

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
6805917

Sources:
NCI
CALCITONIN BIRC5

Interaction Score: 0.59

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16222118

Sources:
NCI

GuideToPharmacology: 135651700
- Version: 29-September-2020
Alternate Names:

CALCA Gene Symbol (for Endogenous Peptides)

CALCITONIN GuideToPharmacology Ligand Name

Drug Info:

Name of the Ligand Species (if a Peptide) Human

Publications:
TdgClinicalTrial: CALCITONIN
- Version: January-2014
Alternate Names:

Drug Info:

FDA Approval approved

Drug Indications antiosteoporotic agent

Drug Class Small molecule

Publications:

NCI: CALCITONIN

Version: 14-September-2017

Alternate Names:

C329 NCI drug code

Drug Info:

Publications:

Thomas et al., 2005, Calcitonin induces apoptosis resistance in prostate cancer cell lines against cytotoxic drugs via the Akt/survivin pathway., Cancer Biol. Ther.

Deftos et al., 1982, Changes in plasma bone GLA protein during treatment of bone disease., Calcif. Tissue Int.

Yaoi et al., 2003, Expression and localization of prohormone convertase PC1 in the calcitonin-producing cells of the bullfrog ultimobranchial gland., J. Histochem. Cytochem.

ChemblDrugs: chembl:CHEMBL3989767
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Trial Name	BN-002,Capsitonin
Novel drug target	Established target
Trial Name	ViaDerm-Calcitonin

CALCA	Gene Symbol (for Endogenous Peptides)
CALCITONIN	GuideToPharmacology Ligand Name

CALCITONIN Drug Record

CALCITONIN chembl:CHEMBL3989767 Approved

Alternate Names:

Drug Info:

Publications:

CALCITONIN PCSK1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14566018

Sources: NCI

CALCITONIN SPP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8013390

Sources: NCI

CALCITONIN CALCR

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name BN-002,Capsitonin Novel drug target Established target Trial Name ViaDerm-Calcitonin

PMIDs: None found

Sources: TdgClinicalTrial GuideToPharmacology

CALCITONIN PTH

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 227233

Sources: NCI

CALCITONIN BGLAP

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 6805917

Sources: NCI

CALCITONIN BIRC5

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16222118

Sources: NCI

GuideToPharmacology: 135651700

Alternate Names: CALCA Gene Symbol (for Endogenous Peptides) CALCITONIN GuideToPharmacology Ligand Name

Drug Info: Name of the Ligand Species (if a Peptide) Human

Publications:

TdgClinicalTrial: CALCITONIN

Alternate Names:

Drug Info: FDA Approval approved Drug Indications antiosteoporotic agent Drug Class Small molecule

Publications:

NCI: CALCITONIN

Alternate Names: C329 NCI drug code

Drug Info:

ChemblDrugs: chembl:CHEMBL3989767

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
14566018

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8013390

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name BN-002,Capsitonin

Novel drug target Established target

Trial Name ViaDerm-Calcitonin

PMIDs:
None found

Sources:
TdgClinicalTrial GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
227233

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
6805917

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16222118

Sources:
NCI

Alternate Names:

CALCA Gene Symbol (for Endogenous Peptides)

CALCITONIN GuideToPharmacology Ligand Name

Drug Info:

Name of the Ligand Species (if a Peptide) Human

Drug Info:

FDA Approval approved

Drug Indications antiosteoporotic agent

Drug Class Small molecule

Alternate Names:

C329 NCI drug code