• Interaction Score: 1.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 1.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 1.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 0.95

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 0.95

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 0.95

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 0.4

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23375793


    Sources:
    DTC

  • Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type breast cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    25436981


    Sources:
    JAX-CKB

  • Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy AZD8055 + Binimetinib
    Indication/Tumor Type lung squamous cell carcinoma
    Response Type sensitive

    PMIDs:
    26544513


    Sources:
    JAX-CKB

  • Interaction Score: 0.14

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase mTOR inhibitor
    Specific Action of the Ligand Inhibition

  • Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Approval Status Preclinical - Cell culture
    Indication/Tumor Type pancreatic ductal adenocarcinoma
    combination therapy AZD8055 + SCH772984


    Sources:
    JAX-CKB

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy AZD4547 + AZD8055
    Indication/Tumor Type lung adenocarcinoma
    Response Type sensitive

    PMIDs:
    26359452


    Sources:
    JAX-CKB

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type head and neck squamous cell carcinoma
    Response Type predicted – sensitive
    Approval Status Preclinical - Cell culture

    PMIDs:
    28446642


    Sources:
    JAX-CKB

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy AZD8055 + Selumetinib
    Indication/Tumor Type colorectal cancer
    Response Type sensitive


    Sources:
    JAX-CKB

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type breast cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    25436981


    Sources:
    JAX-CKB