DGIdb - ATENOLOL Drug Record

ATENOLOL chembl:CHEMBL24 Approved

Alternate Names:

ESATENOLOL
ATENIX-100
IBINOLO
VASATEN
TENORMIN 25
ATENAMIN
ANTIPRESSAN
TENORMIN
TENORMIN L.S.
TOTAMOL
UNIBLOC
ATENIX-25
ATENIX-50
ATENOLOL
C07AB03
ICI 66082
KENTOL
ICI-66082
TREDOL
XATEN
ATENOL FECOFAR
2-(P-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ACETAMIDE
PREMORINE
TENORMIN®
PRINORM
LOTENAL
HIPRES
ATEROL
ATENOL TROM
ATENOLOLUM [INN-LATIN]
TENOBLOCK
DURAATENOLOL
ATENOLOL [USAN:BAN:INN:JAN]
BLOCOTENOL
ATENOL AL
EVITOCOR
SERTEN
NORMITEN
TENOBLOC
ATENOL VON CT
NORMALOL
ATENOLOL (JAN/USP)
FARNORMIN
ATENBLOCK
TENOPRIN
ATENIL
UNILOC
WESIPIN
ATENOLIN
ATENOL COPHAR
LOTEN
SELES BETA
TENORETIC
ATENOL QUESADA
SCHEINPHARM ATENOL
ATENOL-WOLFF
JUVENTAL
TENORMINE
ATENOL GADOR
BETABLOK
VASCOTEN
ATENOLOLUM
NOTEN
HYPOTEN
BETATOP GE
CARDIOPRESS
FELO-BITS
COROTENOL
DURATENOL
ATENOMEL
ATENOL HEUMANN
BETACARD
ATENOL-RATIOPHARM
ATENOL PB
BLOKIUM
ANSELOL
ATENOL 1A PHARMA
TENSIMIN
ATENOL ATID
ALTOL
SERVITENOL
PANAPRES
INTERNOLOL
ATECARD
ATENOL NORDIC
APO-ATENOLOL
TENIDON
MYOCORD®
ATENOL CT
AIRCRIT
ATENOL GNR
ALINOR
STERMIN
TENOLOL
1-P-CARBAMOYLMETHYLPHENOXY-3-ISOPROPYLAMINO-2-PROPANOL
TENORMINE [FRENCH]
SELOBLOC
CARDAXEN
ATENI
ATENOL ACIS
MYOCORD
ATENOL GENERICON
ATENDOL
ATENET
PRENOLOL
4-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)BENZENEACETAMIDE
ATEHEXAL
LO-TEN
PLENACOR
BETASYN
ATENOL-MEPHA
ORADAY
ATEREAL
ATENOL NM PHARMA
PRENORMINE
ATENOL TIKA
ORMIDOL
ATENOL MSD
JENATENOL
ATENOL STADA
ATCARDIL
NORMITEN®
CUXANORM
VERICORDIN
rxcui:1202
drugbank:00335
chemidplus:29122-68-7
pubchem.compound:2249
chembl:CHEMBL24

Drug Info:

Year of Approval	1981
Drug Class	antihypertensive agents
Drug Class	anti-arrhythmia agents
FDA Approval	1981
Drug Class	small molecule
Drug Indications	Antihypertensive Agents
Drug Indications	Anti-Arrhythmia Agents

(5 More Sources)

Publications:

Iniesta R et al., 2019, Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals., Hypertension
Kayser et al., 1989, Changes in serum phosphate during beta-blockade in healthy men are not due to changes in the renal handling of phosphate., J. Intern. Med.
Liljedahl U et al., 2004, Single nucleotide polymorphisms predict the change in left ventricular mass in response to antihypertensive treatment., J Hypertens
Filigheddu F et al., 2010, Haplotypes of the adrenergic system predict the blood pressure response to beta-blockers in women with essential hypertension., Pharmacogenomics
el Tayar N et al., 1988, Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists., J Med Chem
Rau T et al., 2012, Impact of the β1-adrenoceptor Arg389Gly polymorphism on heart-rate responses to bisoprolol and carvedilol in heart-failure patients., Clin Pharmacol Ther
Huntgeburth M et al., 2011, The Arg389Gly β1-adrenoceptor gene polymorphism influences the acute effects of β-adrenoceptor blockade on contractility in the human heart., Clin Res Cardiol
Baudhuin LM et al., 2010, Relation of ADRB1, CYP2D6, and UGT1A1 polymorphisms with dose of, and response to, carvedilol or metoprolol therapy in patients with chronic heart failure., Am J Cardiol
Metra M et al., 2010, Role of beta-adrenergic receptor gene polymorphisms in the long-term effects of beta-blockade with carvedilol in patients with chronic heart failure., Cardiovasc Drugs Ther
Chen L et al., 2007, Arg389Gly-beta1-adrenergic receptors determine improvement in left ventricular systolic function in nonischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilol., Pharmacogenet Genomics
Lobmeyer MT et al., 2007, Synergistic polymorphisms of beta1 and alpha2C-adrenergic receptors and the influence on left ventricular ejection fraction response to beta-blocker therapy in heart failure., Pharmacogenet Genomics
Liu J et al., 2006, beta1-Adrenergic receptor polymorphisms influence the response to metoprolol monotherapy in patients with essential hypertension., Clin Pharmacol Ther
Terra SG et al., 2005, Beta1-adrenergic receptor polymorphisms and left ventricular remodeling changes in response to beta-blocker therapy., Pharmacogenet Genomics
de Groote P et al., 2005, Association between beta-1 and beta-2 adrenergic receptor gene polymorphisms and the response to beta-blockade in patients with stable congestive heart failure., Pharmacogenet Genomics
Terra SG et al., 2005, beta-Adrenergic receptor polymorphisms and responses during titration of metoprolol controlled release/extended release in heart failure., Clin Pharmacol Ther
Liu et al., 2003, Gly389Arg polymorphism of beta1-adrenergic receptor is associated with the cardiovascular response to metoprolol., Clin. Pharmacol. Ther.
Mialet Perez J et al., 2003, Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure., Nat Med
White HL et al., 2003, An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals with heart failure: a MERIT-HF sub-study., Eur J Heart Fail
Johnson et al., 2003, Beta 1-adrenergic receptor polymorphisms and antihypertensive response to metoprolol., Clin. Pharmacol. Ther.
O'Shaughnessy KM et al., 2000, The gain-of-function G389R variant of the beta1-adrenoceptor does not influence blood pressure or heart rate response to beta-blockade in hypertensive subjects., Clin Sci (Lond)
Sofowora GG et al., 2003, A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade., Clin Pharmacol Ther
Alberti et al., 1997, Mechanism and pressor relevance of the short-term cardiovascular and renin excitatory actions of the selective A2A-adenosine receptor agonists., J. Cardiovasc. Pharmacol.
Schäfer et al., 2000, Hypertrophic effect of selective beta(1)-adrenoceptor stimulation on ventricular cardiomyocytes from adult rat., Am. J. Physiol., Cell Physiol.
Brown et al., 2002, Dietary Mg(2+) supplementation restores impaired vasoactive responses in isolated rat aorta induced by chronic ethanol consumption., Eur. J. Pharmacol.
Horinouchi et al., 2007, Different changes of plasma membrane beta-adrenoceptors in rat heart after chronic administration of propranolol, atenolol and bevantolol., Life Sci.
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Nuttall et al., 2003, A comparison of the beta1-selectivity of three beta1-selective beta-blockers., J Clin Pharm Ther
Iaccarino G et al., 2005, beta-Blockade and increased dyslipidemia in patients bearing Glu27 variant of beta2 adrenergic receptor gene., Pharmacogenomics J
Magvanjav O et al., 2017, Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials., J Am Heart Assoc
Kurland L et al., 2004, Angiotensinogen gene polymorphisms: relationship to blood pressure response to antihypertensive treatment. Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial., Am J Hypertens
Kurland L et al., 2001, Angiotensin converting enzyme gene polymorphism predicts blood pressure response to angiotensin II receptor type 1 antagonist treatment in hypertensive patients., J Hypertens
Vandell AG et al., 2012, G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension., Hypertension
Chang SW et al., 2018, Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes., Pharmacogenomics J
Liljedahl et al., 2004, Single nucleotide polymorphisms in the apolipoprotein B and low density lipoprotein receptor genes affect response to antihypertensive treatment., BMC Cardiovasc Disord
Chen et al., 2006, [Effects of atenolol and metoprolol on cardiomyocyte apoptosis and related gene expression after acute myocardial infarction in rats]., Zhongguo Yi Xue Ke Xue Yuan Xue Bao
Beitelshees AL et al., 2009, CACNA1C gene polymorphisms, cardiovascular disease outcomes, and treatment response., Circ Cardiovasc Genet
Rimpelä JM et al., 2017, Replicated evidence for aminoacylase 3 and nephrin gene variations to predict antihypertensive drug responses., Pharmacogenomics
Hallberg et al., 2004, Transforming growth factor beta1 genotype and change in left ventricular mass during antihypertensive treatment--results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA)., Clin Cardiol
Dudley C et al., 1996, Prediction of patient responses to antihypertensive drugs using genetic polymorphisms: investigation of renin-angiotensin system genes., J Hypertens
Price ET et al., 2011, Liver X receptor α gene polymorphisms and variable cardiovascular outcomes in patients treated with antihypertensive therapy: results from the INVEST-GENES study., Pharmacogenet Genomics
Hallberg P et al., 2004, Gender-specific association between preproendothelin-1 genotype and reduction of systolic blood pressure during antihypertensive treatment--results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA)., Clin Cardiol
Yeh et al., 2006, Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment., Am. J. Hypertens.

ATENOLOL STN1

Interaction Score: 3.75

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
31327267

Sources:
PharmGKB
ATENOLOL RRP1B

Interaction Score: 3.75

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
31327267

Sources:
PharmGKB
ATENOLOL TBX2

Interaction Score: 3.75

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
31327267

Sources:
PharmGKB
ATENOLOL ACY3

Interaction Score: 1.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
28353407

Sources:
PharmGKB
ATENOLOL PROX1

Interaction Score: 1.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL PLEKHH2

Interaction Score: 1.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
27670767

Sources:
PharmGKB
ATENOLOL ZMAT4

Interaction Score: 1.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL GALNT2

Interaction Score: 1.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL XIRP2

Interaction Score: 1.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL ALDH1A2

Interaction Score: 1.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
29097388

Sources:
PharmGKB
ATENOLOL SLC4A1

Interaction Score: 0.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL GRK4

Interaction Score: 0.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22949529

Sources:
PharmGKB
ATENOLOL DPYS

Interaction Score: 0.63

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL SLC25A31

Interaction Score: 0.63

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL LRRC15

Interaction Score: 0.63

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL ADRB1

Interaction Score: 0.61

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Beta-1 adrenergic receptor antagonist

Direct Interaction yes

Specific Action of the Ligand Antagonist

PMIDs:
2903243 22617224 21311897 20643254 20352314 20235788 18075464 17496726 16815314 15864115 15861037 15735607 14534524 14502278 12921807 12844134 11787477 12709726 9300315 10913016 12065078 17628611 11752352

Sources:
DTC TdgClinicalTrial ChemblInteractions TEND GuideToPharmacology PharmGKB TTD
ATENOLOL GJA1

Interaction Score: 0.47

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16448880

Sources:
NCI
ATENOLOL AGT

Interaction Score: 0.4

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14700505 11593098

Sources:
PharmGKB
ATENOLOL FTO

Interaction Score: 0.38

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL EDN1

Interaction Score: 0.31

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15188945

Sources:
PharmGKB
ATENOLOL GNB3

Interaction Score: 0.29

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20235788

Sources:
PharmGKB
ATENOLOL LDLR

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15453913

Sources:
NCI PharmGKB
ATENOLOL PTH

Interaction Score: 0.22

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2649632

Sources:
NCI
ATENOLOL PLA2G4A

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL NR1H3

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21562465

Sources:
PharmGKB
ATENOLOL PRKCB

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL ACE

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11593098 8728305 12844134

Sources:
PharmGKB
ATENOLOL CACNA1C

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20031608

Sources:
PharmGKB
ATENOLOL TGFB1

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15049387

Sources:
NCI
ATENOLOL BAX

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16995309

Sources:
NCI
ATENOLOL ADRB2

Interaction Score: 0.05

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

PMIDs:
12795776 16027735

Sources:
GuideToPharmacology PharmGKB
ATENOLOL ADRA2A

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15614026

Sources:
PharmGKB
ATENOLOL PTGS2

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ATENOLOL ABCB1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB

TEND: ATENOLOL
- Version: 01-August-2011
Alternate Names:

Drug Info:

Drug Class anti-arrhythmia agents

Drug Class antihypertensive agents

Year of Approval 1981

Publications:
TdgClinicalTrial: ATENOLOL
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Anti-Arrhythmia Agents

Drug Indications Antihypertensive Agents

Drug Class small molecule

Publications:

NCI: ATENOLOL

Version: 14-September-2017

Alternate Names:

C28836 NCI drug code

Drug Info:

Publications:

Chen et al., 2006, [Effects of atenolol and metoprolol on cardiomyocyte apoptosis and related gene expression after acute myocardial infarction in rats]., Zhongguo Yi Xue Ke Xue Yuan Xue Bao

Hallberg et al., 2004, Transforming growth factor beta1 genotype and change in left ventricular mass during antihypertensive treatment--results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA)., Clin Cardiol

Liljedahl et al., 2004, Single nucleotide polymorphisms in the apolipoprotein B and low density lipoprotein receptor genes affect response to antihypertensive treatment., BMC Cardiovasc Disord

DTC: ATENOLOL
- Version: 02-September-2020
Alternate Names:

CHEMBL24 ChEMBL Drug ID

Drug Info:

Publications:

el Tayar N et al., 1988, Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists., J Med Chem

PharmGKB: atenolol

Version: 18-August-2020

Alternate Names:

Drug Info:

Publications:

Iniesta R et al., 2019, Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals., Hypertension

Magvanjav O et al., 2017, Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials., J Am Heart Assoc

Chang SW et al., 2018, Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes., Pharmacogenomics J

TTD: Atenolol
- Version: 2020.06.01
Alternate Names:

D01UXC TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL24
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL24
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:
GuideToPharmacology: 135649971
- Version: 29-September-2020
Alternate Names:

Drug Info:

Publications:

Mechanism of Interaction	Beta-1 adrenergic receptor antagonist
Direct Interaction	yes
Specific Action of the Ligand	Antagonist

Specific Action of the Ligand	Antagonist
Endogenous Drug?	False

ATENOLOL Drug Record

ATENOLOL chembl:CHEMBL24 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 31327267

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 31327267

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 31327267

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 28353407

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 27670767

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 29097388

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22949529

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Beta-1 adrenergic receptor antagonist Direct Interaction yes Specific Action of the Ligand Antagonist

PMIDs: 2903243 22617224 21311897 20643254 20352314 20235788 18075464 17496726 16815314 15864115 15861037 15735607 14534524 14502278 12921807 12844134 11787477 12709726 9300315 10913016 12065078 17628611 11752352

Sources: DTC TdgClinicalTrial ChemblInteractions TEND GuideToPharmacology PharmGKB TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16448880

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14700505 11593098

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Interaction Types & Directionality:

n/a

PMIDs:
31327267

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
31327267

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
31327267

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
28353407

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
27670767

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
29097388

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
22949529

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Beta-1 adrenergic receptor antagonist

Direct Interaction yes

Specific Action of the Ligand Antagonist

PMIDs:
2903243 22617224 21311897 20643254 20352314 20235788 18075464 17496726 16815314 15864115 15861037 15735607 14534524 14502278 12921807 12844134 11787477 12709726 9300315 10913016 12065078 17628611 11752352

Sources:
DTC TdgClinicalTrial ChemblInteractions TEND GuideToPharmacology PharmGKB TTD

Interaction Types & Directionality:

n/a

PMIDs:
16448880

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
14700505 11593098

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
15188945

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
20235788

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
15453913

Sources:
NCI PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
2649632

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
21562465

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a