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ARFORMOTEROL Drug Record

  • Summary
  • Interactions
  • Claims
  • ARFORMOTEROL chembl:CHEMBL1363 Approved

    Alternate Names:

    ARFORMOTEROL
    FORMOTEROL R,R-FORM
    (-)-FORMOTEROL
    YM-08316
    BROVANA®
    (R,R)-FORMOTEROL
    rxcui:304962
    chembl:CHEMBL1363
    pubchem.compound:3083544
    chemidplus:67346-49-0
    drugbank:01274

    Drug Info:

    FDA Approval 2006
    Drug Class small molecule
    Drug Indications Bronchodilator Agents
    Drug Class bronchodilator agents
    Year of Approval 2006
    Drug Categories agents producing tachycardia
    Drug Categories agents that produce hypertension
    Drug Categories cytochrome p-450 substrates
    Drug Categories drugs that are mainly renally excreted
    Drug Categories potential qtc-prolonging agents
    Drug Categories qtc prolonging agents
    (4 More Sources)

    Publications:

    Cazzola et al., 2010, Arformoterol tartrate in the treatment of COPD., Expert Rev Respir Med
    2004, Arformoterol: (R,R)-eformoterol, (R,R)-formoterol, arformoterol tartrate, eformoterol-sepracor, formoterol-sepracor, R,R-eformoterol, R,R-formoterol., Drugs R D
    Op't Holt, 2007, Inhaled beta agonists., Respir Care
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Matera et al., 2007, ultra-long-acting beta2-adrenoceptor agonists: an emerging therapeutic option for asthma and COPD?, Drugs
    Cazzola et al., 2005, Ultra long-acting beta 2-agonists in development for asthma and chronic obstructive pulmonary disease., Expert Opin Investig Drugs
    Baumgartner et al., 2007, Nebulized arformoterol in patients with COPD: a 12-week, multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled trial., Clin Ther
    Kharidia et al., 2008, A pharmacokinetic/pharmacodynamic study comparing arformoterol tartrate inhalation solution and racemic formoterol dry powder inhaler in subjects with chronic obstructive pulmonary disease., Pulm Pharmacol Ther
  • ARFORMOTEROL   ADRB2

    Interaction Score: 1.13

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Specific Action of the Ligand Agonist

    PMIDs:
    20406080 14725487 17594727 11752352 17352511 16022567 17472819 18501650


    Sources:
    TEND TdgClinicalTrial TTD DrugBank GuideToPharmacology

  • ARFORMOTEROL   UGT1A1

    Interaction Score: 0.73

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    FDA PharmGKB

  • ARFORMOTEROL   ADRB1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Agonist

    PMIDs:
    None found


    Sources:
    GuideToPharmacology

  • ARFORMOTEROL   CYP2D6

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    FDA PharmGKB

  • DrugBank: DB01274

    • Version: 5.1.7

    Alternate Names:
    ARFORMOTEROL DrugBank Drug Name
    67346-49-0 CAS Number
    Brovana Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups investigational

    Publications:
    Cazzola et al., 2010, Arformoterol tartrate in the treatment of COPD., Expert Rev Respir Med
    2004, Arformoterol: (R,R)-eformoterol, (R,R)-formoterol, arformoterol tartrate, eformoterol-sepracor, formoterol-sepracor, R,R-eformoterol, R,R-formoterol., Drugs R D
    Op't Holt, 2007, Inhaled beta agonists., Respir Care

  • TEND: ARFORMOTEROL

    • Version: 01-August-2011

    Alternate Names:
    ARFORMOTEROL Primary Drug Name

    Drug Info:
    Year of Approval 2006
    Drug Class bronchodilator agents

    Publications:

  • TdgClinicalTrial: ARFORMOTEROL

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Bronchodilator Agents
    Drug Class small molecule
    FDA Approval 2006

    Publications:

  • GuideToPharmacology: 187051782

    • Version: 29-September-2020

    Alternate Names:
    ARFORMOTEROL GuideToPharmacology Ligand Name

    Drug Info:

    Publications:

  • TTD: Arformoterol

    • Version: 2020.06.01

    Alternate Names:
    D0D1DI TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1363

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • PharmGKB: arformoterol

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:

  • FDA: Arformoterol

    • Version: 04-September-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21