DGIdb - ARFORMOTEROL Drug Record

ARFORMOTEROL chembl:CHEMBL1363 Approved

Alternate Names:

ARFORMOTEROL
FORMOTEROL R,R-FORM
(-)-FORMOTEROL
YM-08316
BROVANA®
(R,R)-FORMOTEROL
rxcui:304962
chembl:CHEMBL1363
pubchem.compound:3083544
chemidplus:67346-49-0
drugbank:01274

Drug Info:

FDA Approval	2006
Drug Class	small molecule
Drug Indications	Bronchodilator Agents
Drug Class	bronchodilator agents
Year of Approval	2006
Drug Categories	agents producing tachycardia
Drug Categories	agents that produce hypertension
Drug Categories	cytochrome p-450 substrates
Drug Categories	drugs that are mainly renally excreted
Drug Categories	potential qtc-prolonging agents
Drug Categories	qtc prolonging agents

(4 More Sources)

Publications:

Cazzola et al., 2010, Arformoterol tartrate in the treatment of COPD., Expert Rev Respir Med
2004, Arformoterol: (R,R)-eformoterol, (R,R)-formoterol, arformoterol tartrate, eformoterol-sepracor, formoterol-sepracor, R,R-eformoterol, R,R-formoterol., Drugs R D
Op't Holt, 2007, Inhaled beta agonists., Respir Care
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Matera et al., 2007, ultra-long-acting beta2-adrenoceptor agonists: an emerging therapeutic option for asthma and COPD?, Drugs
Cazzola et al., 2005, Ultra long-acting beta 2-agonists in development for asthma and chronic obstructive pulmonary disease., Expert Opin Investig Drugs
Baumgartner et al., 2007, Nebulized arformoterol in patients with COPD: a 12-week, multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled trial., Clin Ther
Kharidia et al., 2008, A pharmacokinetic/pharmacodynamic study comparing arformoterol tartrate inhalation solution and racemic formoterol dry powder inhaler in subjects with chronic obstructive pulmonary disease., Pulm Pharmacol Ther

ARFORMOTEROL ADRB2

Interaction Score: 1.13

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

Specific Action of the Ligand Agonist

PMIDs:
20406080 14725487 17594727 11752352 17352511 16022567 17472819 18501650

Sources:
TEND TdgClinicalTrial TTD DrugBank GuideToPharmacology
ARFORMOTEROL UGT1A1

Interaction Score: 0.73

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
FDA PharmGKB
ARFORMOTEROL ADRB1

Interaction Score: 0.11

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Agonist

PMIDs:
None found

Sources:
GuideToPharmacology
ARFORMOTEROL CYP2D6

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
FDA PharmGKB

DrugBank: DB01274

Version: 5.1.7

Alternate Names:

ARFORMOTEROL DrugBank Drug Name

67346-49-0 CAS Number

Brovana Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups investigational

Publications:

Cazzola et al., 2010, Arformoterol tartrate in the treatment of COPD., Expert Rev Respir Med

2004, Arformoterol: (R,R)-eformoterol, (R,R)-formoterol, arformoterol tartrate, eformoterol-sepracor, formoterol-sepracor, R,R-eformoterol, R,R-formoterol., Drugs R D

Op't Holt, 2007, Inhaled beta agonists., Respir Care

TEND: ARFORMOTEROL
- Version: 01-August-2011
Alternate Names:

ARFORMOTEROL Primary Drug Name

Drug Info:

Year of Approval 2006

Drug Class bronchodilator agents

Publications:
TdgClinicalTrial: ARFORMOTEROL
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Bronchodilator Agents

Drug Class small molecule

FDA Approval 2006

Publications:
GuideToPharmacology: 187051782
- Version: 29-September-2020
Alternate Names:

ARFORMOTEROL GuideToPharmacology Ligand Name

Drug Info:

Publications:
TTD: Arformoterol
- Version: 2020.06.01
Alternate Names:

D0D1DI TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1363
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
PharmGKB: arformoterol
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:
FDA: Arformoterol
- Version: 04-September-2020
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target
Specific Action of the Ligand	Agonist

Direct Interaction?	False
Endogenous Drug?	False
Specific Action of the Ligand	Agonist

ARFORMOTEROL	DrugBank Drug Name
67346-49-0	CAS Number
Brovana	Drug Brand

Drug Type	small molecule
Drug Groups	approved
Drug Groups	investigational

ARFORMOTEROL Drug Record

ARFORMOTEROL chembl:CHEMBL1363 Approved

Alternate Names:

Drug Info:

Publications:

ARFORMOTEROL ADRB2

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name - Novel drug target Established target Specific Action of the Ligand Agonist

PMIDs: 20406080 14725487 17594727 11752352 17352511 16022567 17472819 18501650

Sources: TEND TdgClinicalTrial TTD DrugBank GuideToPharmacology

ARFORMOTEROL UGT1A1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: FDA PharmGKB

ARFORMOTEROL ADRB1

Interaction Types & Directionality: agonist (activating)

Interaction Info: Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Agonist

PMIDs: None found

Sources: GuideToPharmacology

ARFORMOTEROL CYP2D6

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: FDA PharmGKB

DrugBank: DB01274

Alternate Names: ARFORMOTEROL DrugBank Drug Name 67346-49-0 CAS Number Brovana Drug Brand

Drug Info: Drug Type small molecule Drug Groups approved Drug Groups investigational

TEND: ARFORMOTEROL

Alternate Names: ARFORMOTEROL Primary Drug Name

Drug Info: Year of Approval 2006 Drug Class bronchodilator agents

Publications:

TdgClinicalTrial: ARFORMOTEROL

Alternate Names:

Drug Info: Drug Indications Bronchodilator Agents Drug Class small molecule FDA Approval 2006

Publications:

GuideToPharmacology: 187051782

Alternate Names: ARFORMOTEROL GuideToPharmacology Ligand Name

Drug Info:

Publications:

TTD: Arformoterol

Alternate Names: D0D1DI TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1363

Alternate Names:

Drug Info:

Publications:

PharmGKB: arformoterol

Alternate Names:

Drug Info:

Publications:

FDA: Arformoterol

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

Specific Action of the Ligand Agonist

PMIDs:
20406080 14725487 17594727 11752352 17352511 16022567 17472819 18501650

Sources:
TEND TdgClinicalTrial TTD DrugBank GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
FDA PharmGKB

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Agonist

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
FDA PharmGKB

Alternate Names:

ARFORMOTEROL DrugBank Drug Name

67346-49-0 CAS Number

Brovana Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups investigational

Alternate Names:

ARFORMOTEROL Primary Drug Name

Drug Info:

Year of Approval 2006

Drug Class bronchodilator agents

Drug Info:

Drug Indications Bronchodilator Agents

Drug Class small molecule

FDA Approval 2006

Alternate Names:

ARFORMOTEROL GuideToPharmacology Ligand Name

Alternate Names:

D0D1DI TTD Drug ID