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AMPRENAVIR Drug Record

  • Summary
  • Interactions
  • Claims
  • AMPRENAVIR chembl:CHEMBL116 Approved

    Alternate Names:

    AGENERASE
    AMPRENAVIR
    141 W94
    141W94
    J05AE05
    VX-478
    KVX-478
    (3S)-TETRAHYDRO-3-FURANYL ((1S,2R)-3-(((4-AMINOPHENYL)SULFONYL)(2-METHYLPROPYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)CARBAMATE
    rxcui:228656
    chembl:CHEMBL116
    pubchem.compound:65016
    chemidplus:161814-49-9
    drugbank:00701

    Drug Info:

    (0 More Sources)

    Publications:

    Granfors et al., 2006, Differential inhibition of cytochrome P450 3A4, 3A5 and 3A7 by five human immunodeficiency virus (HIV) protease inhibitors in vitro., Basic Clin. Pharmacol. Toxicol.
    Lenhard et al., 2000, HIV protease inhibitors block adipogenesis and increase lipolysis in vitro., Antiviral Res.
  • AMPRENAVIR   TFAP2A

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10996400


    Sources:
    NCI

  • AMPRENAVIR   CYP3A5

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16433896


    Sources:
    NCI

  • AMPRENAVIR   SLCO1B1

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • AMPRENAVIR   ABCB1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • NCI: AMPRENAVIR

    • Version: 14-September-2017

    Alternate Names:
    C28824 NCI drug code

    Drug Info:

    Publications:
    Lenhard et al., 2000, HIV protease inhibitors block adipogenesis and increase lipolysis in vitro., Antiviral Res.
    Granfors et al., 2006, Differential inhibition of cytochrome P450 3A4, 3A5 and 3A7 by five human immunodeficiency virus (HIV) protease inhibitors in vitro., Basic Clin. Pharmacol. Toxicol.

  • TTD: Amprenavir

    • Version: 2020.06.01

    Alternate Names:
    D0A0OO TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL116

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • PharmGKB: amprenavir

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21