• Interaction Score: 0.99

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name alvespimycin hydrochloride, KOS-1022 (DMAG), NSC-707545
    Novel drug target Novel Target

    PMIDs:
    17603540


  • Interaction Score: 0.48

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name alvespimycin hydrochloride, KOS-1022 (DMAG), NSC-707545
    Specific Action of the Ligand Inhibition

  • Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type non-small cell lung carcinoma
    Response Type predicted – sensitive
    Approval Status Preclinical - Cell line xenograft

    PMIDs:
    26483207


    Sources:
    JAX-CKB

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Alvespimycin + Vorinostat
    Indication/Tumor Type Advanced Solid Tumor
    Response Type sensitive

    PMIDs:
    26009011


    Sources:
    JAX-CKB