• TTK 7272 Druggable Genome

    Alternate Names:

    7272
    TTK PROTEIN KINASE
    TTK
    CT96
    ESK
    MPH1
    MPS1
    MPS1L1
    PYT
    604092
    12401
    ENSG00000112742
    OTTHUMG00000015088
    P33981
    DUAL SPECIFICITY PROTEIN KINASE TTK
    TTK_HUMAN
    BE0003791
    DUAL SPECIFICITY PROTEIN KINASE TTK (EC 2.7.1.-) (PHOSPHOTYROSINE PICKED THREONINE KINASE) (PYT). [SOURCE:UNIPROT/SWISSPROT;ACC:P33981]
    2264
    NP_003309
    NM_001166691
    Phosphotyrosine picked threonine-protein kinase

    Gene Info:

    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Uniprot Evidence 1: Evidence at protein level
    Gene Biotype PROTEIN_CODING"
    GuideToPharmacology Gene Category Name TTK family
    GuideToPharmacology Gene Category ID 637
    GuideToPharmacology Gene Type enzyme
    Human Readable Name SERINE THREONINE KINASE
    (6 More Sources)
  • Interaction Types:
    inhibitor

    Interaction Info:
    Details of the Assay for Interaction <i>In vitro</i> assay using a His-tagged catalytic domain fragment of MPS1 (amino acids 510–857).
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Dual specificity protein kinase TTK inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Dual specificity protein kinase TTK inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    • Version: 90_38

    Alternate Names:
    TTK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    7272 Entrez Gene ID
    TTK protein kinase HUGO Gene Name
    12401 HUGO Gene ID

    Gene Info:
    GuideToPharmacology Gene Category Name TTK family
    GuideToPharmacology Gene Category ID 637
    GuideToPharmacology Gene Type enzyme

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    P33981 Uniprot Accession
    TTK Uniprot Gene Name
    ENSG00000112742 Ensembl Gene Id

    Gene Info:
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    DUAL SPECIFICITY PROTEIN KINASE TTK (EC 2.7.1.-) (PHOSPHOTYROSINE PICKED THREONINE KINASE) (PYT). [SOURCE:UNIPROT/SWISSPROT;ACC:P33981] Description
    TTK Display Id
    ENSG00000112742 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    7272 Entrez Gene Id
    TTK Gene Symbol

    Gene Info:
    Human Readable Name SERINE THREONINE KINASE

    Publications:

    • Version: 5.0.8

    Alternate Names:
    TTK DrugBank Gene Name
    P33981 UniProt Accession
    7272 Entrez Gene Id

    Gene Info:

    • Version: 27-September-2017

    Alternate Names:
    TTK protein kinase GuideToPharmacology Name
    P33981 UniProtKB ID

    Gene Info:

    Publications:

  • GO: TTK

    • Version: 27-September-2017

    Alternate Names:
    P33981 UniProtKB ID
    TTK_HUMAN GO Gene Synonym
    MPS1 GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000112742 Gene Symbol
    TTK Ensembl Id

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    MPS1L1 GENE_SYMBOL
    TTK GENE_SYMBOL
    Dual specificity protein kinase TTK UNIPROT

    Gene Info:

    Publications: