• TNFRSF10B 8795 Druggable Genome

    Alternate Names:

    8795
    TNF RECEPTOR SUPERFAMILY MEMBER 10B
    TNFRSF10B
    CD262
    DR5
    KILLER
    KILLER/DR5
    TRAIL-R2
    TRAILR2
    TRICK2
    TRICK2A
    TRICK2B
    TRICKB
    ZTNFR9
    603612
    11905
    ENSG00000120889
    OTTHUMG00000097826
    Tumor necrosis factor receptor superfamily member 10B
    Death receptor 5
    TNF-related apoptosis-inducing ligand receptor 2
    CD_antigen=CD262
    TRAIL receptor 2
    UNQ160/PRO186
    TR10B_HUMAN
    O14763
    TRAIL-R2/D5
    TRAIL-R1/DR4,R2/D5
    TTDC00266
    1880
    BE0003433

    Gene Info:

    Target Class Receptors
    Target Subclass Receptors
    Target Subclass TNFNGF
    Gene Biotype PROTEIN_CODING"
    (7 More Sources)

    Publications:

  • Interaction Types:
    agonist
    antibody

    Interaction Info:
    Mechanism of Interaction Tumor necrosis factor receptor superfamily member 10B agonist
    Direct Interaction yes
    Specific Action of the Ligand Agonist

    Publications:

  • Interaction Types:
    agonist
    antibody

    Interaction Info:
    Notes
    Mechanism of Interaction Tumor necrosis factor receptor superfamily member 10B agonist
    Direct Interaction yes

    Publications:

  • Interaction Types:
    agonist
    antibody

    Interaction Info:
    Notes
    Direct Interaction yes
    Mechanism of Interaction Tumor necrosis factor receptor superfamily member 10B agonist

    Publications:

  • Interaction Types:
    antibody

    Interaction Info:
    Trial Name lexatumumab, HGS-ETR2, TRAIL-R2
    Novel drug target Novel Target
    Notes

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Mechanism of Interaction Tumor necrosis factor receptor superfamily member 10B agonist
    Direct Interaction yes

    Publications:

  • Interaction Types:
    antibody

    Interaction Info:

    Publications:

  • Interaction Types:
    agonist
    antibody

    Interaction Info:

    Publications:

    • Version: 90_38

    Alternate Names:
    TNFRSF10B Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    TNFRSF10B Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass Receptors
    Target Subclass TNFNGF

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    death receptor 5 GuideToPharmacology Name
    O14763 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 20-Jun-2017

    Alternate Names:
    8795 Entrez Gene Id
    TNFRSF10B MyCancerGenome Gene Symbol
    TRAIL-R2/D5 MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    DR5 Gene Symbol

    Gene Info:

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    TRAIL-R2 Gene Symbol

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    O14763 UniProtKB ID
    TR10B_HUMAN GO Gene Synonym
    DR5 GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B Gene Name
    CD262 Gene Synonym
    ENSG00000120889 Ensembl Gene Id

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000120889 Gene Symbol
    TNFRSF10B Ensembl Id

    Gene Info:

    Publications:

    • Version: 5.0.8

    Alternate Names:
    TNFRSF10B DrugBank Gene Name
    O14763 UniProt Accession
    8795 Entrez Gene Id

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    KILLER GENE_SYMBOL
    TRAILR2 GENE_SYMBOL
    TRICK2 GENE_SYMBOL

    Gene Info:

    Publications: