• TACR2 6865 Druggable Genome

    Alternate Names:

    6865
    TACHYKININ RECEPTOR 2
    TACR2
    NK2R
    NKNAR
    SKR
    TAC2R
    162321
    11527
    ENSG00000075073
    OTTHUMG00000018377
    TTDC00090
    NK-2R
    TACHYKININ NEUROKININ 2 RECEPTOR
    NEUROKININ A RECEPTOR
    SUBSTANCE-K RECEPTOR
    NK-2 RECEPTOR
    P21452
    SUBSTANCE-K RECEPTOR (SKR) (NEUROKININ A RECEPTOR) (NK-2 RECEPTOR) (NK-2R) (TACHYKININ RECEPTOR 2). [SOURCE:UNIPROT/SWISSPROT;ACC:P21452]
    NK2R_HUMAN
    361
    NK<sub>2</sub> receptor
    NP_001048
    NM_001057

    Gene Info:

    Gene Biotype PROTEIN_CODING"
    Human Readable Name DRUGGABLE GENOME
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Uniprot Status Swiss-Prot
    Interpro Type Family
    Uniprot Evidence 2: Evidence at transcript level
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Interpro Acc IPR000276
    Interpro Name GPCR, rhodopsin-like, 7TM
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin
    GuideToPharmacology Gene Category Name Tachykinin receptors
    GuideToPharmacology Gene Category ID 62
    GuideToPharmacology Gene Type gpcr
    (7 More Sources)

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Mechanism of Interaction Neurokinin 2 receptor antagonist

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Trial Name Saredutant, SR 48968
    Novel drug target Novel Target
    Specific Action of the Ligand Antagonist

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:

    Publications:

    • Version: 90_38

    Alternate Names:
    TACR2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    TACR2 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    TACR2 Uniprot Gene Name
    P21452 Uniprot Accession
    6865 Entrez Gene Id

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Type Family
    Uniprot Evidence 2: Evidence at transcript level

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    tachykinin receptor 2 HUGO Gene Name
    11527 HUGO Gene ID
    TACR2 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name Tachykinin receptors
    GuideToPharmacology Gene Category ID 62
    GuideToPharmacology Gene Type gpcr

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    TACR2 Display Id
    SUBSTANCE-K RECEPTOR (SKR) (NEUROKININ A RECEPTOR) (NK-2 RECEPTOR) (NK-2R) (TACHYKININ RECEPTOR 2). [SOURCE:UNIPROT/SWISSPROT;ACC:P21452] Description
    ENSG00000075073 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    6865 Entrez Gene Id
    TACR2 Gene Symbol

    Gene Info:
    Human Readable Name G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000075073 Gene Symbol
    TACR2 Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    NK<sub>2</sub> receptor GuideToPharmacology Name
    P21452 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    P21452 UniProtKB ID
    NK2R_HUMAN GO Gene Synonym
    NK2R GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    SKR Gene Synonym
    P21452 Uniprot Accession
    NK-2R Gene Synonym

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    NKNAR GENE_SYMBOL
    TAC2R GENE_SYMBOL
    TACR2 GENE_SYMBOL

    Gene Info:

    Publications: