• RYR3 6263 Druggable Genome

    Alternate Names:

    6263
    RYANODINE RECEPTOR 3
    RYR3
    RYR-3
    180903
    10485
    ENSG00000198838
    OTTHUMG00000172253
    HBRR
    RYR3_HUMAN
    Q15413
    749
    Type 3 ryanodine receptor
    Brain-type ryanodine receptor
    Brain ryanodine receptor-calcium release channel
    RYANODINE RECEPTOR 3 (BRAIN-TYPE RYANODINE RECEPTOR) (RYR3) (RYR-3) (BRAIN RYANODINE RECEPTOR-CALCIUM RELEASE CHANNEL). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15413]

    Gene Info:

    GuideToPharmacology Gene Category Name Ryanodine receptor
    GuideToPharmacology Gene Category ID 125
    GuideToPharmacology Gene Type lgic
    Initial Gene Query RyR3
    Counted Citations from 1950-2000 197
    Gene Category Ion Channel
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Ion transport domain
    Human Readable Name ION CHANNEL
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR001870
    Interpro Short Name B30.2/SPRY
    Interpro Acc IPR005821
    Interpro Type Domain
    Human Readable Name B30_2 SPRY DOMAIN
    Uniprot Status Swiss-Prot
    Interpro Short Name Ion_trans_dom
    Interpro Name B30.2/SPRY domain
    Gene Biotype PROTEIN_CODING"
    (5 More Sources)

    Publications:

  • Interaction Types:
    activator

    Interaction Info:
    Interaction Context cytosolic
    Specific Action of the Ligand None
    Details of Interaction endogenous; mM range

    Publications:

  • Interaction Types:
    activator

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction pharmacological; mM range
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist
    activator

    Interaction Info:
    Interaction Context cytosolic
    Specific Action of the Ligand None
    Details of Interaction endogenous; μM range

    Publications:

  • Interaction Types:
    activator

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction pharmacological; nM - μM range
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Interaction Context cytosolic
    Specific Action of the Ligand Antagonist
    Details of Interaction mM range

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Mechanism of Interaction Ryanodine receptor 3 antagonist
    Direct Interaction yes

    Publications:

    • Version: 90_38

    Alternate Names:
    RYR3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    RYANODINE RECEPTOR 3 (BRAIN-TYPE RYANODINE RECEPTOR) (RYR3) (RYR-3) (BRAIN RYANODINE RECEPTOR-CALCIUM RELEASE CHANNEL). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15413] Description
    RYR3 Display Id
    ENSG00000198838 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    Q15413 Uniprot Accession
    ENSG00000198838 Ensembl Gene Id
    RYR3_HUMAN Uniprot Id

    Gene Info:
    Interpro Name Ion transport domain
    Human Readable Name ION CHANNEL
    Uniprot Evidence 1: Evidence at protein level

    Publications:

    • Version: February-2014

    Alternate Names:
    6263 Entrez Gene ID

    Gene Info:
    Initial Gene Query RyR3
    Counted Citations from 1950-2000 197
    Gene Category Ion Channel

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    ryanodine receptor 3 HUGO Gene Name
    10485 HUGO Gene ID
    RYR3 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name Ryanodine receptor
    GuideToPharmacology Gene Category ID 125
    GuideToPharmacology Gene Type lgic

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    RyR3 GuideToPharmacology Name
    Q15413 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000198838 Gene Symbol
    RYR3 Ensembl Id

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    HBRR GENE_SYMBOL
    RYR3 GENE_SYMBOL
    Ryanodine receptor 3 UNIPROT

    Gene Info:

    Publications:

  • GO: RYR3

    • Version: 27-September-2017

    Alternate Names:
    Q15413 UniProtKB ID
    RYR3_HUMAN GO Gene Synonym
    HBRR GO Gene Synonym

    Gene Info:

    Publications: