• PSMB5 5693 Druggable Genome

    Alternate Names:

    5693
    PROTEASOME SUBUNIT BETA 5
    PSMB5
    LMPX
    MB1
    X
    600306
    9542
    ENSG00000100804
    OTTHUMG00000028713
    Multicatalytic endopeptidase complex epsilon chain
    Proteasome subunit MB1
    Proteasome subunit X
    Proteasome epsilon chain
    Proteasome subunit beta type-5
    Macropain epsilon chain
    Proteasome chain 6
    P28074
    PSB5_HUMAN
    BE0002348
    2406
    NP_001124197|NP_001138404|NP_002788
    NM_001130725|NM_001144932|NM_002797
    proteasome (prosome, macropain) subunit, beta type, 5
    Proteasome

    Gene Info:

    Target Main Class Enzymes
    Target Subclass 3.4.25.1
    Gene Biotype PROTEIN_CODING"
    GuideToPharmacology Gene Category Name T1: Proteasome
    GuideToPharmacology Gene Category ID 752
    GuideToPharmacology Gene Type enzyme
    Target Class Enzymes
    Target Subclass EC:3.4.25.1
    Human Readable Name PROTEASE
    (7 More Sources)
  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

  • Interaction Types:
    inhibitor

    Interaction Info:
    Trial Name Velcade
    Novel drug target Established target
    Specific Action of the Ligand Inhibition

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction 20S Proteasome inhibitor
    Direct Interaction yes

    Publications:

    • Version: 90_38

    Alternate Names:
    PSMB5 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    5693 Entrez Gene Id
    PSMB5 Gene Symbol
    PSB5_HUMAN Uniprot Id

    Gene Info:
    Target Main Class Enzymes
    Target Subclass 3.4.25.1

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    proteasome (prosome, macropain) subunit, beta type, 5 HUGO Gene Name
    9542 HUGO Gene ID
    PSMB5 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name T1: Proteasome
    GuideToPharmacology Gene Category ID 752
    GuideToPharmacology Gene Type enzyme

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    PSMB5 Gene Symbol
    5693 Entrez Gene Id

    Gene Info:
    Human Readable Name PROTEASE

    Publications:

    • Version: January-2014

    Alternate Names:
    PSMB5 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.4.25.1

    Publications:

    • Version: 5.0.8

    Alternate Names:
    PSMB5 DrugBank Gene Name
    P28074 UniProt Accession
    5693 Entrez Gene Id

    Gene Info:

    • Version: chembl_23

    Alternate Names:
    MB1 GENE_SYMBOL
    X GENE_SYMBOL
    PSMB5 GENE_SYMBOL

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    proteasome subunit beta 5 GuideToPharmacology Name
    P28074 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000100804 Gene Symbol
    PSMB5 Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    P28074 UniProtKB ID
    PSB5_HUMAN GO Gene Synonym
    LMPX GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 20-Jun-2017

    Alternate Names:
    5693 Entrez Gene Id
    PSMB5 MyCancerGenome Gene Symbol
    Proteasome MyCancerGenome Reported Gene Name

    Gene Info:

    Publications: