• PRKCI 5584 Druggable Genome

    Alternate Names:

    5584
    PROTEIN KINASE C IOTA
    PRKCI
    DXS1179E
    PKCI
    nPKC-iota
    600539
    9404
    ENSG00000163558
    OTTHUMG00000150214
    P41743
    1490
    NP_002731
    NM_002740
    protein kinase C, iota
    PKC
    BE0003889
    KPCI_HUMAN
    aPKC-lambda/iota
    PRKC-lambda/iota
    Atypical protein kinase C-lambda/iota
    Protein kinase C iota type
    PROTEIN KINASE C, IOTA TYPE (EC 2.7.1.37) (NPKC-IOTA) (ATYPICAL PROTEIN KINASE C-LAMBDA/IOTA) (APKC-LAMBDA/IOTA) (PRKC-LAMBDA/IOTA). [SOURCE:UNIPROT/SWISSPROT;ACC:P41743]

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:2.7.11.13
    GuideToPharmacology Gene Category Name Iota subfamily
    GuideToPharmacology Gene Category ID 535
    GuideToPharmacology Gene Type enzyme
    Human Readable Name SERINE THREONINE KINASE
    Gene Biotype PROTEIN_CODING"
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Human Readable Name DRUGGABLE GENOME
    Human Readable Name KINASE
    Interpro Acc IPR002290
    Uniprot Status Swiss-Prot
    Interpro Type Domain
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    (8 More Sources)
  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name PEP005
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    • Version: 90_38

    Alternate Names:
    PRKCI Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    PRKCI Uniprot Gene Name
    PROTEIN KINASE C IOTA TYPE Uniprot Protein Name
    ENSG00000163558 Ensembl Gene Id

    Gene Info:
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Human Readable Name DRUGGABLE GENOME
    Human Readable Name KINASE

    Publications:

    • Version: January-2014

    Alternate Names:
    PRKCI Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.13

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000163558 Ensembl Gene Id
    PRKCI Display Id
    PROTEIN KINASE C, IOTA TYPE (EC 2.7.1.37) (NPKC-IOTA) (ATYPICAL PROTEIN KINASE C-LAMBDA/IOTA) (APKC-LAMBDA/IOTA) (PRKC-LAMBDA/IOTA). [SOURCE:UNIPROT/SWISSPROT;ACC:P41743] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    protein kinase C, iota HUGO Gene Name
    9404 HUGO Gene ID
    PRKCI Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name Iota subfamily
    GuideToPharmacology Gene Category ID 535
    GuideToPharmacology Gene Type enzyme

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    5584 Entrez Gene Id
    PRKCI Gene Symbol

    Gene Info:
    Human Readable Name SERINE THREONINE KINASE

    Publications:

    • Version: 5.0.8

    Alternate Names:
    PRKCI DrugBank Gene Name
    P41743 UniProt Accession
    5584 Entrez Gene Id

    Gene Info:

    • Version: 27-September-2017

    Alternate Names:
    protein kinase C iota GuideToPharmacology Name
    P41743 UniProtKB ID

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    DXS1179E GENE_SYMBOL
    PRKCI GENE_SYMBOL
    Protein kinase C iota type UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000163558 Gene Symbol
    PRKCI Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    P41743 UniProtKB ID
    KPCI_HUMAN GO Gene Synonym
    DXS1179E GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 20-Jun-2017

    Alternate Names:
    5584 Entrez Gene Id
    PRKCI MyCancerGenome Gene Symbol
    PKC MyCancerGenome Reported Gene Name

    Gene Info:

    Publications: