• PRKCE 5581 Druggable Genome

    Alternate Names:

    5581
    PROTEIN KINASE C EPSILON
    PRKCE
    PKCE
    nPKC-epsilon
    176975
    9401
    ENSG00000171132
    OTTHUMG00000128817
    Protein kinase C epsilon type
    Q02156
    PKC
    PKC-epsilon
    1486
    BE0003431
    TTDC00066
    PKC EPSILON
    PROTEIN KINASE C, EPSILON TYPE
    PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON). [SOURCE:UNIPROT/SWISSPROT;ACC:Q02156]
    protein kinase C, epsilon
    NP_005391
    NM_005400
    KPCE_HUMAN

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:2.7.11.13
    Initial Gene Query PKC epsilon
    Counted Citations from 1950-2000 1023
    Gene Category Kinase
    Human Readable Name DRUGGABLE GENOME
    GuideToPharmacology Gene Category Name Eta subfamily
    GuideToPharmacology Gene Category ID 534
    GuideToPharmacology Gene Type enzyme
    Gene Biotype PROTEIN_CODING"
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR002290
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE
    Interpro Type Domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name SERINE THREONINE KINASE
    (10 More Sources)

    Publications:

  • Interaction Types:
    activator

    Interaction Info:
    Trial Name KAI-1455
    Novel drug target Established target

    Publications:

  • Interaction Types:
    activator

    Interaction Info:
    Specific Action of the Ligand Activation
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name Bryostatin-1
    Novel drug target Established target
    Trial Name Bryostatin

    Publications:

    • Version: 90_38

    Alternate Names:
    PRKCE Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    PROTEIN KINASE C EPSILON TYPE Uniprot Protein Name
    PRKCE Uniprot Gene Name
    5581 Entrez Gene Id

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR002290
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    protein kinase C, epsilon HUGO Gene Name
    9401 HUGO Gene ID
    PRKCE Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name Eta subfamily
    GuideToPharmacology Gene Category ID 534
    GuideToPharmacology Gene Type enzyme

    Publications:

    • Version: February-2014

    Alternate Names:
    5581 Entrez Gene ID

    Gene Info:
    Initial Gene Query PKC epsilon
    Counted Citations from 1950-2000 1023
    Gene Category Kinase

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    5581 Entrez Gene Id
    PRKCE Gene Symbol

    Gene Info:
    Human Readable Name SERINE THREONINE KINASE

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    PRKCE Display Id
    PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON). [SOURCE:UNIPROT/SWISSPROT;ACC:Q02156] Description
    ENSG00000171132 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    PRKCE Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.13

    Publications:

    • Version: chembl_23

    Alternate Names:
    PKCE GENE_SYMBOL
    PRKCE GENE_SYMBOL
    Protein kinase C epsilon type UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000171132 Gene Symbol
    PRKCE Ensembl Id

    Gene Info:

    Publications:

    • Version: 20-Jun-2017

    Alternate Names:
    5581 Entrez Gene Id
    PRKCE MyCancerGenome Gene Symbol
    PKC-epsilon MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    protein kinase C epsilon GuideToPharmacology Name
    Q02156 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q02156 UniProtKB ID
    KPCE_HUMAN GO Gene Synonym
    PKCE GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    PROTEIN KINASE C, EPSILON TYPE Gene Name
    ENSG00000171132 Ensembl Gene Id
    PKC EPSILON Gene Synonym

    Gene Info:

    Publications:

    • Version: 5.0.8

    Alternate Names:
    PRKCE DrugBank Gene Name
    Q02156 UniProt Accession
    5581 Entrez Gene Id

    Gene Info:

    Publications: