• NPY4R 5540 Druggable Genome

    Alternate Names:

    5540
    NEUROPEPTIDE Y RECEPTOR Y4
    NPY4R
    NPY4-R
    PP1
    PPYR1
    Y4
    601790
    9329
    ENSG00000204174
    OTTHUMG00000018108
    P50391
    307
    Y<sub>4</sub> receptor
    TTDC00043
    pancreatic polypeptide receptor 1
    NEUROPEPTIDE Y RECEPTOR TYPE 4
    ENSG00000204174; ENSG00000263039
    BE0002418
    NPY4R_HUMAN
    ENSG00000263039

    Gene Info:

    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin
    Gene Biotype PROTEIN_CODING"
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Uniprot Evidence 2: Evidence at transcript level
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR000276
    Interpro Name GPCR, rhodopsin-like, 7TM
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Uniprot Status Swiss-Prot
    Interpro Type Family
    (6 More Sources)

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Trial Name TM30338,Obinepitide
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False
    Endogenous Drug? True

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True
    Trial Name PYY3-36

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

  • Interaction Types:
    allosteric modulator

    Interaction Info:
    Details of the Assay for Interaction <i>In vitro</i> elevation of agonist-induced accumulation of inositol phosphate to 185% of control.
    Specific Action of the Ligand Positive
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Mechanism of Interaction Neuropeptide Y receptor type 4 agonist
    Direct Interaction yes
    Trial Name TM30339

    Publications:

    • Version: 90_38

    Alternate Names:
    NPY4R Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    PPYR1 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000204174 Ensembl Gene Id
    P50391 Uniprot Accession
    5540 Entrez Gene Id

    Gene Info:
    Uniprot Evidence 2: Evidence at transcript level
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR000276

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    PPYR1 Gene Symbol
    5540 Entrez Gene Id

    Gene Info:
    Human Readable Name G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: chembl_23

    Alternate Names:
    PPYR1 GENE_SYMBOL
    NPY4R GENE_SYMBOL
    Neuropeptide Y receptor type 4 UNIPROT

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Y<sub>4</sub> receptor GuideToPharmacology Name
    P50391 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000204174 Gene Symbol
    NPY4R Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    P50391 UniProtKB ID
    NPY4R_HUMAN GO Gene Synonym
    PPYR1 GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    ENSG00000204174; ENSG00000263039 Ensembl Gene Id
    NPY4R Gene Synonym
    5540 Entrez Gene Id

    Gene Info:

    Publications:

    • Version: 5.0.8

    Alternate Names:
    NPY4R DrugBank Gene Name
    P50391 UniProt Accession
    5540 Entrez Gene Id

    Gene Info:

    Publications: