• NCSTN 23385 Druggable Genome

    Alternate Names:

    23385
    NICASTRIN
    NCSTN
    ATAG1874
    605254
    17091
    ENSG00000162736
    OTTHUMG00000033110
    KIAA0253
    UNQ1874/PRO4317
    NICA_HUMAN
    Q92542
    Gamma-secretase

    Gene Info:

    Gene Biotype PROTEIN_CODING"
    Target Class Miscellaneous
    Target Subclass Miscellaneous
    Target Subclass gamma secretase subunit
    (3 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Gamma-secretase inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    modulator

    Interaction Info:
    Mechanism of Interaction Gamma-secretase modulator
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Gamma-secretase inhibitor
    Direct Interaction yes
    Trial Name BMS-708163

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Gamma-secretase inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name BMS-299897
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name GSI-136
    Novel drug target Novel Target

    Publications:

    • Version: 90_38

    Alternate Names:
    NCSTN Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    NCSTN Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Miscellaneous
    Target Subclass gamma secretase subunit

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000162736 Gene Symbol
    NCSTN Ensembl Id

    Gene Info:

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    NCSTN Gene Symbol

    Gene Info:

    Publications:

    • Version: 20-Jun-2017

    Alternate Names:
    23385 Entrez Gene Id
    NCSTN MyCancerGenome Gene Symbol
    Gamma-secretase MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    KIAA0253 GENE_SYMBOL
    NCSTN GENE_SYMBOL
    Nicastrin UNIPROT

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q92542 UniProtKB ID
    NICA_HUMAN GO Gene Synonym
    KIAA0253 GO Gene Synonym

    Gene Info:

    Publications: