• MAPK11 5600 Druggable Genome

    Alternate Names:

    5600
    MITOGEN-ACTIVATED PROTEIN KINASE 11
    MAPK11
    P38B
    P38BETA2
    PRKM11
    SAPK2
    SAPK2B
    p38-2
    p38Beta
    602898
    6873
    ENSG00000185386
    OTTHUMG00000150226
    MK11_HUMAN
    Q15759
    PA30618
    BE0003390
    1500
    NP_002742
    NM_002751
    MAP kinase p38 beta
    MAPK 11
    MAP kinase 11
    Stress-activated protein kinase 2b
    Mitogen-activated protein kinase p38 beta
    MITOGEN-ACTIVATED PROTEIN KINASE 11 (EC 2.7.1.37) (MITOGEN-ACTIVATED PROTEIN KINASE P38 BETA) (MAP KINASE P38 BETA) (P38B) (P38-2) (STRESS- ACTIVATED PROTEIN KINASE-2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15759]

    Gene Info:

    Gene Biotype PROTEIN_CODING"
    Has Variant Annotation false
    Is VIP false
    Human Readable Name SERINE THREONINE KINASE
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Acc IPR002290
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    GuideToPharmacology Gene Category Name p38 subfamily
    GuideToPharmacology Gene Category ID 519
    GuideToPharmacology Gene Type enzyme
    Target Class Enzymes
    Target Subclass EC:2.7.11.24
    (9 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction MAP kinase p38 beta inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Details of the Assay for Interaction Inhibition of p38β2.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction MAP kinase p38 beta inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction MAP kinase p38 beta inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name KC706
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name CPSI-2364
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name pirfenidone,Esbriet , Deskar, Pirespa
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name ARRY-614
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name BMS-582949
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name ARRY-797
    Novel drug target Novel Target

    Publications:

    • Version: 90_38

    Alternate Names:
    MAPK11 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    MAPK11 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.24

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    MITOGEN-ACTIVATED PROTEIN KINASE 11 (EC 2.7.1.37) (MITOGEN-ACTIVATED PROTEIN KINASE P38 BETA) (MAP KINASE P38 BETA) (P38B) (P38-2) (STRESS- ACTIVATED PROTEIN KINASE-2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15759] Description
    ENSG00000185386 Ensembl Gene Id
    MAPK11 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    5600 Entrez Gene Id
    MAPK11 Gene Symbol

    Gene Info:
    Human Readable Name SERINE THREONINE KINASE

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    mitogen-activated protein kinase 11 HUGO Gene Name
    6873 HUGO Gene ID
    MAPK11 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name p38 subfamily
    GuideToPharmacology Gene Category ID 519
    GuideToPharmacology Gene Type enzyme

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    Q15759 Uniprot Accession
    5600 Entrez Gene Id
    MAPK11 Uniprot Gene Name

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain

    Publications:

    • Version: 12-July-2012

    Alternate Names:
    ENSG00000185386 Ensembl Gene Id
    MAPK11 Gene Symbol
    mitogen-activated protein kinase 11 Gene Name

    Gene Info:
    Has Variant Annotation false
    Is VIP false

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000185386 Gene Symbol
    MAPK11 Ensembl Id

    Gene Info:

    Publications:

    • Version: 5.0.8

    Alternate Names:
    MAPK11 DrugBank Gene Name
    Q15759 UniProt Accession
    5600 Entrez Gene Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q15759 UniProtKB ID
    MK11_HUMAN GO Gene Synonym
    PRKM11 GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    mitogen-activated protein kinase 11 GuideToPharmacology Name
    Q15759 UniProtKB ID

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    SAPK2 GENE_SYMBOL
    SAPK2B GENE_SYMBOL
    MAPK11 GENE_SYMBOL

    Gene Info:

    Publications:

    • Version: 30-February-2014

    Alternate Names:

    Gene Info:

    Publications: