• MAP3K5 4217 Druggable Genome

    Alternate Names:

    4217
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
    MAP3K5
    ASK1
    MAPKKK5
    MEKK5
    602448
    6857
    ENSG00000197442
    OTTHUMG00000015647
    2080
    NM_005923
    NP_005914
    Q99683
    MAPK/ERK kinase kinase 5
    MEKK 5
    MEK kinase 5
    Apoptosis signal-regulating kinase 1
    ASK-1
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (EC 2.7.1.37) (MAPK/ERK KINASE KINASE 5) (MEK KINASE 5) (MEKK 5) (APOPTOSIS SIGNAL- REGULATING KINASE 1) (ASK-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q99683]
    M3K5_HUMAN

    Gene Info:

    Gene Biotype PROTEIN_CODING"
    GuideToPharmacology Gene Category Name STE11 family
    GuideToPharmacology Gene Category ID 621
    GuideToPharmacology Gene Type enzyme
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain
    Interpro Acc IPR002290
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name SERINE THREONINE KINASE
    (5 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Mitogen-activated protein kinase kinase kinase 5 inhibitor
    Direct Interaction yes

    Publications:

    • Version: 90_38

    Alternate Names:
    MAP3K5 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (EC 2.7.1.37) (MAPK/ERK KINASE KINASE 5) (MEK KINASE 5) (MEKK 5) (APOPTOSIS SIGNAL- REGULATING KINASE 1) (ASK-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q99683] Description
    MAP3K5 Display Id
    ENSG00000197442 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    MAP3K5 Uniprot Gene Name
    M3K5_HUMAN Uniprot Id
    Q99683 Uniprot Accession

    Gene Info:
    Interpro Type Domain
    Interpro Acc IPR002290
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    mitogen-activated protein kinase kinase kinase 5 HUGO Gene Name
    6857 HUGO Gene ID
    MAP3K5 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name STE11 family
    GuideToPharmacology Gene Category ID 621
    GuideToPharmacology Gene Type enzyme

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    MAP3K5 Gene Symbol
    4217 Entrez Gene Id

    Gene Info:
    Human Readable Name SERINE THREONINE KINASE

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    mitogen-activated protein kinase kinase kinase 5 GuideToPharmacology Name
    Q99683 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q99683 UniProtKB ID
    M3K5_HUMAN GO Gene Synonym
    ASK1 GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000197442 Gene Symbol
    MAP3K5 Ensembl Id

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    MEK kinase 5 UNIPROT
    MAPKKK5 GENE_SYMBOL
    MEKK5 GENE_SYMBOL

    Gene Info:

    Publications: