• MAP3K12 7786 Druggable Genome

    Alternate Names:

    7786
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12
    MAP3K12
    DLK
    MEKK12
    MUK
    ZPK
    ZPKP1
    600447
    6851
    ENSG00000139625
    OTTHUMG00000169854
    Q12852
    M3K12_HUMAN
    Mixed lineage kinase
    MAPK-upstream kinase
    Leucine-zipper protein kinase
    Dual leucine zipper bearing kinase
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12 (EC 2.7.1.37) (MIXED LINEAGE KINASE) (LEUCINE-ZIPPER PROTEIN KINASE) (ZPK) (DUAL LEUCINE ZIPPER BEARING KINASE) (DLK) (MAPK-UPSTREAM KINASE) (MUK). [SOURCE:UNIPROT/SWISSPROT;ACC:Q12852]
    2072
    NP_006292
    NM_006301

    Gene Info:

    Human Readable Name SERINE THREONINE KINASE
    Gene Biotype PROTEIN_CODING"
    Human Readable Name DRUGGABLE GENOME
    Human Readable Name KINASE
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Interpro Type Domain
    Interpro Acc IPR001245
    Uniprot Evidence 1: Evidence at protein level
    GuideToPharmacology Gene Category Name LZK subfamily
    GuideToPharmacology Gene Category ID 523
    GuideToPharmacology Gene Type enzyme
    (4 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Mitogen-activated protein kinase kinase kinase 12 inhibitor
    Direct Interaction yes

    Publications:

    • Version: 90_38

    Alternate Names:
    MAP3K12 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    7786 Entrez Gene Id
    MAP3K12 Gene Symbol

    Gene Info:
    Human Readable Name SERINE THREONINE KINASE

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    7786 Entrez Gene Id
    MAP3K12 Uniprot Gene Name
    Q12852 Uniprot Accession

    Gene Info:
    Human Readable Name KINASE
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    mitogen-activated protein kinase kinase kinase 12 HUGO Gene Name
    6851 HUGO Gene ID
    MAP3K12 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name LZK subfamily
    GuideToPharmacology Gene Category ID 523
    GuideToPharmacology Gene Type enzyme

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    MAP3K12 Display Id
    ENSG00000139625 Ensembl Gene Id
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12 (EC 2.7.1.37) (MIXED LINEAGE KINASE) (LEUCINE-ZIPPER PROTEIN KINASE) (ZPK) (DUAL LEUCINE ZIPPER BEARING KINASE) (DLK) (MAPK-UPSTREAM KINASE) (MUK). [SOURCE:UNIPROT/SWISSPROT;ACC:Q12852] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000139625 Gene Symbol
    MAP3K12 Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q12852 UniProtKB ID
    M3K12_HUMAN GO Gene Synonym
    ZPK GO Gene Synonym

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    ZPK GENE_SYMBOL
    MAP3K12 GENE_SYMBOL
    Mitogen-activated protein kinase kinase kinase 12 UNIPROT

    Gene Info:

    Publications: