• MAP3K1 4214 Druggable GenomeClinically Actionable

    Alternate Names:

    4214
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1
    MAP3K1
    MAPKKK1
    MEKK
    MEKK 1
    MEKK1
    SRXY6
    600982
    6848
    ENSG00000095015
    OTTHUMG00000059486
    2069
    Q13233
    M3K1_HUMAN
    BE0003430
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 (EC 2.7.1.37) (MAPK/ERK KINASE KINASE 1) (MEK KINASE 1) (MEKK 1) (FRAGMENT). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13233]
    MEK kinase 1
    MAPK/ERK kinase kinase 1
    NP_005912
    NM_005921
    mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

    Gene Info:

    Human Readable Name SERINE THREONINE KINASE
    Gene Biotype PROTEIN_CODING"
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR002290
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Interpro Type Domain
    Source Reported Gene Name MAP3K1
    Gene Category CLINICALLY ACTIONABLE
    GuideToPharmacology Gene Category Name STE11 family
    GuideToPharmacology Gene Category ID 621
    GuideToPharmacology Gene Type enzyme
    (8 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    Publications:

    • Version: 90_38

    Alternate Names:
    MAP3K1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    Q13233 Uniprot Accession
    4214 Entrez Gene Id
    ENSG00000095015 Ensembl Gene Id

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR002290
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase HUGO Gene Name
    6848 HUGO Gene ID
    MAP3K1 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name STE11 family
    GuideToPharmacology Gene Category ID 621
    GuideToPharmacology Gene Type enzyme

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    MAP3K1 Gene Symbol
    4214 Entrez Gene Id

    Gene Info:
    Human Readable Name SERINE THREONINE KINASE

    Publications:

    • Version: 20-September-2013

    Alternate Names:
    4214 Entrez Gene ID

    Gene Info:
    Source Reported Gene Name MAP3K1
    Gene Category CLINICALLY ACTIONABLE

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000095015 Ensembl Gene Id
    MAP3K1 Display Id
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 (EC 2.7.1.37) (MAPK/ERK KINASE KINASE 1) (MEK KINASE 1) (MEKK 1) (FRAGMENT). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13233] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    mitogen-activated protein kinase kinase kinase 1 GuideToPharmacology Name
    Q13233 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q13233 UniProtKB ID
    M3K1_HUMAN GO Gene Synonym
    MAPKKK1 GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000095015 Gene Symbol
    MAP3K1 Ensembl Id

    Gene Info:

    Publications:

    • Version: 5.0.8

    Alternate Names:
    MAP3K1 DrugBank Gene Name
    Q13233 UniProt Accession
    4214 Entrez Gene Id

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    MEKK GENE_SYMBOL
    MEKK1 GENE_SYMBOL
    MAP3K1 GENE_SYMBOL

    Gene Info:

    Publications:

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Publications: