• ITGB5 3693 Druggable Genome

    Alternate Names:

    3693
    INTEGRIN SUBUNIT BETA 5
    ITGB5
    147561
    6160
    ENSG00000082781
    OTTHUMG00000159432
    P18084
    Integrin beta-5
    ITB5_HUMAN
    INTEGRIN BETA-5 PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P18084]

    Gene Info:

    Target Class Miscellaneous
    Target Subclass Receptor
    Target Subclass integrin
    Gene Biotype PROTEIN_CODING"
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain
    Interpro Name Integrin beta subunit, N-terminal
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR002369
    Uniprot Status Swiss-Prot
    Interpro Short Name Integrin_bsu_N
    (4 More Sources)

    Publications:

  • Interaction Types:
    antagonist
    inhibitor

    Interaction Info:
    Trial Name cilengitide. EMD-121974
    Novel drug target Novel Target
    Mechanism of Interaction Integrin alpha-V/beta-5 antagonist

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Integrin alpha-V/beta-5 inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Mechanism of Interaction Integrin alpha-V/beta-5 antagonist
    Direct Interaction yes
    Trial Name CNTO-95

    Publications:

    • Version: 90_38

    Alternate Names:
    ITGB5 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    ITGB5 Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Receptor
    Target Subclass integrin

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ITB5_HUMAN Uniprot Id
    ITGB5 Uniprot Gene Name
    ENSG00000082781 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain
    Interpro Name Integrin beta subunit, N-terminal

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000082781 Ensembl Gene Id
    ITGB5 Display Id
    INTEGRIN BETA-5 PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P18084] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    ITGB5 GENE_SYMBOL
    Integrin beta-5 UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000082781 Gene Symbol
    ITGB5 Ensembl Id

    Gene Info:

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    ITGB5 Gene Symbol

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    P18084 UniProtKB ID
    ITB5_HUMAN GO Gene Synonym

    Gene Info:

    Publications: