• ITGB1 3688 Druggable Genome

    Alternate Names:

    3688
    INTEGRIN SUBUNIT BETA 1
    ITGB1
    CD29
    FNRB
    GPIIA
    MDF2
    MSK12
    VLA-BETA
    VLAB
    135630
    6153
    ENSG00000150093
    OTTHUMG00000017928
    P05556
    ITB1_HUMAN
    2578
    P08514
    integrin α2β1
    2577
    P56199
    integrin α1β1
    TTDC00148
    BETA(1) INTEGRIN
    CD29 ANTIGEN
    INTEGRIN VLA-4 BETA SUBUNIT
    INTEGRIN BETA-1
    FIBRONECTIN RECEPTOR BETA SUBUNIT
    2580
    integrin α4β1
    P13612
    BE0003575
    INTEGRIN BETA-1 PRECURSOR (FIBRONECTIN RECEPTOR BETA SUBUNIT) (CD29 ANTIGEN) (INTEGRIN VLA-4 BETA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:P05556]
    CD_antigen=CD29
    VLA-4 subunit beta
    Glycoprotein IIa
    Fibronectin receptor subunit beta

    Gene Info:

    Target Class Receptors
    Target Subclass Receptors
    Target Subclass Integrin
    Gene Biotype PROTEIN_CODING"
    Interpro Acc IPR002369
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain
    Interpro Name Integrin beta subunit, N-terminal
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name Integrin_bsu_N
    Uniprot Status Swiss-Prot
    (9 More Sources)

    Publications:

  • Interaction Types:
    inhibitor
    antibody

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist
    antibody

    Interaction Info:
    Notes Targets ALPHA-5/BETA-1 INTEGRIN
    Trial Name volociximab, E10030, Eos200-4
    Novel drug target Established target

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Trial Name SB-683699, T-0047
    Novel drug target Established target
    Mechanism of Interaction Integrin alpha-4/beta-1 antagonist

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Integrin alpha-V/beta-1 inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Mechanism of Interaction Integrin alpha-V/beta-1 antagonist
    Direct Interaction yes

    Publications:

  • Interaction Types:
    antibody

    Interaction Info:
    Notes Targets ALPHA-5/BETA-1 INTEGRIN

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:

    Publications:

  • Interaction Types:
    antibody

    Interaction Info:
    Notes Targets ALPHA-5/BETA-1 INTEGRIN

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name R1295
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    Publications:

    • Version: 90_38

    Alternate Names:
    ITGB1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    ITGB1 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass Receptors
    Target Subclass Integrin

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ITGB1 Display Id
    INTEGRIN BETA-1 PRECURSOR (FIBRONECTIN RECEPTOR BETA SUBUNIT) (CD29 ANTIGEN) (INTEGRIN VLA-4 BETA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:P05556] Description
    ENSG00000150093 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ITGB1 Uniprot Gene Name
    ENSG00000150093 Ensembl Gene Id
    ITB1_HUMAN Uniprot Id

    Gene Info:
    Interpro Acc IPR002369
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain

    Publications:

    • Version: 5.0.8

    Alternate Names:
    ITGB1 DrugBank Gene Name
    P05556 UniProt Accession
    3688 Entrez Gene Id

    Gene Info:

    • Version: 27-September-2017

    Alternate Names:
    integrin α1β1 GuideToPharmacology Name
    P05556 UniProtKB ID
    P56199 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    integrin α4β1 GuideToPharmacology Name
    P05556 UniProtKB ID
    P13612 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    ENSG00000150093 Ensembl Gene Id
    INTEGRIN BETA-1 Gene Name
    3688 Entrez Gene Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    integrin α2β1 GuideToPharmacology Name
    P05556 UniProtKB ID
    P08514 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    P05556 UniProtKB ID
    ITB1_HUMAN GO Gene Synonym
    FNRB GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000150093 Gene Symbol
    ITGB1 Ensembl Id

    Gene Info:

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    ITGB1 Gene Symbol

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    MDF2 GENE_SYMBOL
    MSK12 GENE_SYMBOL
    ITGB1 GENE_SYMBOL

    Gene Info:

    Publications: