• HTR3B 9177 Druggable Genome

    Alternate Names:

    9177
    5-HYDROXYTRYPTAMINE RECEPTOR 3B
    HTR3B
    5-HT3B
    604654
    5298
    ENSG00000149305
    OTTHUMG00000168210
    O95264
    5HT3B_HUMAN
    BE0005839
    5-HT3-B
    Serotonin receptor 3B
    5-HYDROXYTRYPTAMINE (SEROTONIN) RECEPTOR 3B PRECURSOR [SOURCE:REFSEQ_PEPTIDE;ACC:NP_006019]
    TTDC00009
    5-HYDROXY-TRYPTAMINE 3B RECEPTOR
    5-HT-3B
    374
    NP_006019
    NM_006028
    5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
    378
    P46098
    5-HT<sub>3</sub>AB

    Gene Info:

    Target Class Receptors
    Target Subclass TC:1.A.9
    Gene Biotype PROTEIN_CODING"
    Human Readable Name ION CHANNEL
    Interpro Acc IPR006201
    Interpro Type Family
    Interpro Type Domain
    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR006202
    Interpro Short Name Neur_channel
    Uniprot Status Swiss-Prot
    Interpro Short Name Neur_chan_lig-bd
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Neurotransmitter-gated ion-channel
    GuideToPharmacology Gene Category Name 5-HT<sub>3</sub> receptors
    GuideToPharmacology Gene Category ID 68
    GuideToPharmacology Gene Type lgic
    (7 More Sources)

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Mechanism of Interaction Serotonin 3 (5-HT3) receptor antagonist
    Direct Interaction yes

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Mechanism of Interaction Serotonin 3 (5-HT3) receptor antagonist
    Direct Interaction yes

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Mechanism of Interaction Serotonin 3 (5-HT3) receptor antagonist
    Direct Interaction yes

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Agonist
    Endogenous Drug? True
    Direct Interaction? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name Pumosetrag
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name DDP225
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name dolasetron mesylate,Anzemet
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name granisetron nasal spray
    Novel drug target Established target
    Trial Name granisetron (intranasal), TRG

    Publications:

    • Version: 90_38

    Alternate Names:
    HTR3B Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    HTR3B Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass TC:1.A.9

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    5-HYDROXYTRYPTAMINE (SEROTONIN) RECEPTOR 3B PRECURSOR [SOURCE:REFSEQ_PEPTIDE;ACC:NP_006019] Description
    ENSG00000149305 Ensembl Gene Id
    HTR3B Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    5-hydroxytryptamine (serotonin) receptor 3B, ionotropic HUGO Gene Name
    5298 HUGO Gene ID
    HTR3B Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name 5-HT<sub>3</sub> receptors
    GuideToPharmacology Gene Category ID 68
    GuideToPharmacology Gene Type lgic

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    HTR3B Uniprot Gene Name
    O95264 Uniprot Accession
    5HT3B_HUMAN Uniprot Id

    Gene Info:
    Human Readable Name ION CHANNEL
    Interpro Acc IPR006201
    Interpro Type Family

    Publications:

    • Version: 5.0.8

    Alternate Names:
    HTR3B DrugBank Gene Name
    O95264 UniProt Accession
    9177 Entrez Gene Id

    Gene Info:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    9177 Entrez Gene Id
    HTR3B Gene Synonym
    5-HT3B Gene Synonym

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000149305 Gene Symbol
    HTR3B Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    O95264 UniProtKB ID
    5HT3B_HUMAN GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    5-HT<sub>3</sub>AB GuideToPharmacology Name
    P46098 UniProtKB ID
    O95264 UniProtKB ID

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    HTR3B GENE_SYMBOL
    5-hydroxytryptamine receptor 3B UNIPROT
    Serotonin receptor 3B UNIPROT

    Gene Info:

    Publications: