2280 |
FK506 BINDING PROTEIN 1A |
FKBP1A |
FKBP-12 |
FKBP-1A |
FKBP1 |
FKBP12 |
PKC12 |
PKCI2 |
PPIASE |
186945 |
3711 |
ENSG00000088832 |
OTTHUMG00000031666 |
BE0000695 |
P62942 |
Peptidyl-prolyl cis-trans isomerase FKBP1A |
12 kDa FK506-binding protein |
Calstabin-1 |
FK506-binding protein 1A |
Immunophilin FKBP12 |
Rotamase |
PPIase FKBP1A |
12 kDa FKBP |
FKB1A_HUMAN |
FK506-BINDING PROTEIN 1A (EC 5.2.1.8) (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE) (PPIASE) (ROTAMASE) (12 KDA FKBP) (FKBP-12) (IMMUNOPHILIN FKBP12). [SOURCE:UNIPROT/SWISSPROT;ACC:P62942] |
TTDR00122 |
CYCLOPHILIN |
PEPTIDYLPROLYL ISOMERASE |
CYCLOSPORIN A-BINDING PROTEIN |
PEPTIDYL-PROLYL CIS-TRANS ISOMERASE |
2609 |
Target Class | Enzymes |
Target Subclass | EC:5.2.1.8 |
Human Readable Name | DRUGGABLE GENOME |
Interpro Short Name | PPIase_FKBP_dom |
Uniprot Status | Swiss-Prot |
Interpro Acc | IPR001179 |
Interpro Type | Domain |
Interpro Name | Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain |
Uniprot Evidence | 1: Evidence at protein level |
Target Main Class | Enzymes |
Target Subclass | 5.2.1.8 |
Gene Biotype | PROTEIN_CODING" |
inhibitor |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor |
other |
Trial Name | LCP-Siro, sirolimus |
Novel drug target | Established target |
Trial Name | sirolimus, rapamycin,Perceiva |
inhibitor |
Specific Action of the Ligand | Binding |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor |
Mechanism of Interaction | FK506-binding protein 1A inhibitor |
Direct Interaction | yes |
inhibitor |
Mechanism of Interaction | FK506-binding protein 1A inhibitor |
Direct Interaction | yes |
inhibitor |
Mechanism of Interaction | FK506-binding protein 1A inhibitor |
Direct Interaction | yes |
inhibitor |
potentiator |
Direct Interaction | yes |
Mechanism of Interaction | FK506-binding protein 1A inhibitor |
inhibitor |
inhibitor |
inhibitor |
n/a |
n/a |
n/a |
n/a |
n/a |
FKBP1A | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING" |
FKBP1A | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:5.2.1.8 |
FK506-BINDING PROTEIN 1A (EC 5.2.1.8) (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE) (PPIASE) (ROTAMASE) (12 KDA FKBP) (FKBP-12) (IMMUNOPHILIN FKBP12). [SOURCE:UNIPROT/SWISSPROT;ACC:P62942] | Description |
ENSG00000088832 | Ensembl Gene Id |
FKBP1A | Display Id |
Human Readable Name | DRUGGABLE GENOME |
ENSG00000088832 | Ensembl Gene Id |
P62942 | Uniprot Accession |
FKB1A_HUMAN | Uniprot Id |
Interpro Short Name | PPIase_FKBP_dom |
Uniprot Status | Swiss-Prot |
Interpro Acc | IPR001179 |
2280 | Entrez Gene Id |
FKBP1A | Gene Symbol |
ENSG00000088832 | Ensembl Gene Id |
Target Main Class | Enzymes |
Target Subclass | 5.2.1.8 |
FKBP1A | DrugBank Gene Name |
P62942 | UniProt Accession |
2280 | Entrez Gene Id |
FK506 binding protein 1A | GuideToPharmacology Name |
P62942 | UniProtKB ID |
ENSG00000088832 | Gene Symbol |
FKBP1A | Ensembl Id |
FKBP12 | GENE_SYMBOL |
FKBP1A | GENE_SYMBOL |
Peptidyl-prolyl cis-trans isomerase FKBP1A | UNIPROT |
P62942 | UniProtKB ID |
FKB1A_HUMAN | GO Gene Synonym |
FKBP1 | GO Gene Synonym |
PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | Gene Synonym |
CYCLOSPORIN A-BINDING PROTEIN | Gene Synonym |
PEPTIDYLPROLYL ISOMERASE | Gene Synonym |