• F2RL3 9002 Druggable Genome

    Alternate Names:

    9002
    F2R LIKE THROMBIN OR TRYPSIN RECEPTOR 3
    F2RL3
    PAR4
    602779
    3540
    ENSG00000127533
    OTTHUMG00000182647
    PAR4_HUMAN
    Q96RI0
    350
    NP_003941
    NM_003950
    coagulation factor II (thrombin) receptor-like 3
    PROTEINASE-ACTIVATED RECEPTOR 4
    PROTEINASE ACTIVATED RECEPTOR 4 PRECURSOR (PAR-4) (THROMBIN RECEPTOR- LIKE 3) (COAGULATION FACTOR II RECEPTOR-LIKE 3). [SOURCE:UNIPROT/SWISSPROT;ACC:Q96RI0]

    Gene Info:

    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Gene Biotype PROTEIN_CODING"
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin
    GuideToPharmacology Gene Category Name Proteinase-activated receptors
    GuideToPharmacology Gene Category ID 59
    GuideToPharmacology Gene Type gpcr
    Uniprot Status Swiss-Prot
    Interpro Name GPCR, rhodopsin-like, 7TM
    Interpro Acc IPR000276
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Family
    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name 7TM_GPCR_Rhodpsn
    (5 More Sources)

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Details of the Assay for Interaction Antagonism measured in a novel PAC-1 fluorescent αIIbβ3 activation assay.
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Details of the Assay for Interaction Antagonism of PAR4-AP-stimulated human platelet aggregation.
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name TP-508,Chrysalin
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name vorapaxar , SCH-530348
    Novel drug target Novel Target

    Publications:

    • Version: 90_38

    Alternate Names:
    F2RL3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000127533 Ensembl Gene Id
    F2RL3 Display Id
    PROTEINASE ACTIVATED RECEPTOR 4 PRECURSOR (PAR-4) (THROMBIN RECEPTOR- LIKE 3) (COAGULATION FACTOR II RECEPTOR-LIKE 3). [SOURCE:UNIPROT/SWISSPROT;ACC:Q96RI0] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    F2RL3 Gene Symbol
    9002 Entrez Gene Id

    Gene Info:
    Human Readable Name G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    PAR4 GuideToPharmacology Name
    coagulation factor II (thrombin) receptor-like 3 HUGO Gene Name
    3540 HUGO Gene ID

    Gene Info:
    GuideToPharmacology Gene Category Name Proteinase-activated receptors
    GuideToPharmacology Gene Category ID 59
    GuideToPharmacology Gene Type gpcr

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    9002 Entrez Gene Id
    ENSG00000127533 Ensembl Gene Id
    Q96RI0 Uniprot Accession

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Name GPCR, rhodopsin-like, 7TM
    Interpro Acc IPR000276

    Publications:

    • Version: January-2014

    Alternate Names:
    F2RL3 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    PAR4 GuideToPharmacology Name
    Q96RI0 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000127533 Gene Symbol
    F2RL3 Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q96RI0 UniProtKB ID
    PAR4_HUMAN GO Gene Synonym
    PAR4 GO Gene Synonym

    Gene Info:

    Publications: