• CHEK2 11200 Druggable GenomeClinically ActionableDrug Resistance

    Alternate Names:

    11200
    CHECKPOINT KINASE 2
    CHEK2
    CDS1
    CHK2
    HuCds1
    LFS2
    PP1425
    RAD53
    hCds1
    604373
    16627
    ENSG00000183765
    OTTHUMG00000151023
    BE0003381
    O96017
    CHK2_HUMAN
    SERINE/THREONINE-PROTEIN KINASE CHK2 (EC 2.7.1.37) (CDS1). [SOURCE:UNIPROT/SWISSPROT;ACC:O96017]
    SERINE/THREONINE-PROTEIN KINASE CHK2
    1988
    NP_001005735
    NM_001005735
    Cds1 homolog
    CHK2 checkpoint homolog

    Gene Info:

    Gene Biotype PROTEIN_CODING"
    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002290
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name KINASE
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Target Class Enzymes
    Target Subclass EC:2.7.11.1
    Source Reported Gene Name CHEK2
    Gene Category CLINICALLY ACTIONABLE
    GuideToPharmacology Gene Category Name RAD53 family
    GuideToPharmacology Gene Category ID 609
    GuideToPharmacology Gene Type enzyme
    Human Readable Name SERINE THREONINE KINASE
    (9 More Sources)