• C5AR1 728 Druggable Genome

    Alternate Names:

    728
    COMPLEMENT C5A RECEPTOR 1
    C5AR1
    C5A
    C5AR
    C5R1
    CD88
    113995
    1338
    ENSG00000197405
    OTTHUMG00000183504
    C5a anaphylatoxin chemotactic receptor
    CD_antigen=CD88
    C5a-R
    C5a anaphylatoxin chemotactic receptor 1
    C5AR1_HUMAN
    P21730
    C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR (C5A-R) (C5AR) (CD88 ANTIGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P21730]
    32
    C5a<sub>1</sub> receptor
    C5AR_HUMAN
    58503; 728

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Gene Biotype PROTEIN_CODING"
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin
    Interpro Type Family
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Acc IPR000276
    Interpro Name GPCR, rhodopsin-like, 7TM
    (5 More Sources)

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Trial Name CCX168
    Novel drug target Novel Target
    Mechanism of Interaction C5a anaphylatoxin chemotactic receptor antagonist

    Publications:

    • Version: 90_38

    Alternate Names:
    C5AR1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR (C5A-R) (C5AR) (CD88 ANTIGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P21730] Description
    C5R1 Display Id
    ENSG00000197405 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    728 Entrez Gene Id
    C5AR1 Gene Symbol

    Gene Info:
    Human Readable Name G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: January-2014

    Alternate Names:
    C5AR1 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    C5AR1 Uniprot Gene Name
    ENSG00000197405 Ensembl Gene Id
    58503; 728 Entrez Gene Id

    Gene Info:
    Interpro Type Family
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Uniprot Evidence 1: Evidence at protein level

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    C5a<sub>1</sub> receptor GuideToPharmacology Name
    P21730 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000197405 Gene Symbol
    C5AR1 Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    P21730 UniProtKB ID
    C5AR1_HUMAN GO Gene Synonym
    C5AR GO Gene Synonym

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    C5R1 GENE_SYMBOL
    C5AR GENE_SYMBOL
    C5AR1 GENE_SYMBOL

    Gene Info:

    Publications: