• BIRC3 330 Druggable Genome

    Alternate Names:

    330
    BACULOVIRAL IAP REPEAT CONTAINING 3
    BIRC3
    AIP1
    API2
    CIAP2
    HAIP1
    HIAP1
    MALT2
    MIHC
    RNF49
    c-IAP2
    601721
    591
    ENSG00000023445
    OTTHUMG00000167324
    IAP homolog C
    Inhibitor of apoptosis protein 1
    RING finger protein 49
    RING-type E3 ubiquitin transferase BIRC3
    TNFR2-TRAF-signaling complex protein 1
    hIAP-1
    Baculoviral IAP repeat-containing protein 3
    Apoptosis inhibitor 2
    Cellular inhibitor of apoptosis 2
    Retinoic acid receptor-β
    P10826
    2792
    Q13489
    BIRC3_HUMAN

    Gene Info:

    Gene Biotype PROTEIN_CODING"
    Target Class Miscellaneous
    Target Subclass Inhibitor of apoptosis
    (3 More Sources)

    Publications:

  • Interaction Types:
    antagonist
    inhibitor

    Interaction Info:
    Mechanism of Interaction cIAP1/cIAP2 inhibitor
    Direct Interaction yes
    Notes

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Details of the Assay for Interaction BIR3 domain of hcIPA2 (BIRC3)
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Details of the Assay for Interaction Fluorescence polarization assay using hcIAP2 BIR3 domain (residues 238-349)
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Notes

    Publications:

    • Version: 90_38

    Alternate Names:
    BIRC3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    BIRC3 Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Inhibitor of apoptosis

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    baculoviral IAP repeat containing 3 GuideToPharmacology Name
    Q13489 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q13489 UniProtKB ID
    BIRC3_HUMAN GO Gene Synonym
    API2 GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    C-IAP2 Gene Symbol

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000023445 Gene Symbol
    BIRC3 Ensembl Id

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    MIHC GENE_SYMBOL
    RNF49 GENE_SYMBOL
    BIRC3 GENE_SYMBOL

    Gene Info:

    Publications: