• BIRC2 329 Druggable Genome

    Alternate Names:

    329
    BACULOVIRAL IAP REPEAT CONTAINING 2
    BIRC2
    API1
    HIAP2
    Hiap-2
    MIHB
    RNF48
    c-IAP1
    cIAP1
    601712
    590
    ENSG00000110330
    OTTHUMG00000167325
    Q13490
    BIRC2_HUMAN
    2791
    TNFR2-TRAF-signaling complex protein 2
    RING-type E3 ubiquitin transferase BIRC2
    RING finger protein 48
    Inhibitor of apoptosis protein 2
    IAP homolog B
    Cellular inhibitor of apoptosis 1
    Baculoviral IAP repeat-containing protein 2

    Gene Info:

    Target Class Miscellaneous
    Target Subclass Inhibitor of apoptosis
    Gene Biotype PROTEIN_CODING"
    (4 More Sources)

    Publications:

  • Interaction Types:
    antagonist
    inhibitor

    Interaction Info:
    Details of the Assay for Interaction Assay uses recombinantly expressed BIR3 domain of cIAP1
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist
    inhibitor

    Interaction Info:
    Notes
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Details of the Assay for Interaction BIR3 domain of hcIAP1 (BIRC2)
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Details of the Assay for Interaction Fluorescence polarization assay using hcIAP-1 BIR3 domain (residues 253-363)
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

    • Version: 90_38

    Alternate Names:
    BIRC2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: January-2014

    Alternate Names:
    BIRC2 Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Inhibitor of apoptosis

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q13490 UniProtKB ID
    BIRC2_HUMAN GO Gene Synonym
    API1 GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    C-IAP1 Gene Symbol

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000110330 Gene Symbol
    BIRC2 Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    baculoviral IAP repeat containing 2 GuideToPharmacology Name
    Q13490 UniProtKB ID

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    MIHB GENE_SYMBOL
    RNF48 GENE_SYMBOL
    BIRC2 GENE_SYMBOL

    Gene Info:

    Publications:

    • Version: 15-June-2013

    Alternate Names:

    Gene Info:

    Publications: