• BACE2 25825 Druggable Genome

    Alternate Names:

    25825
    BETA-SITE APP-CLEAVING ENZYME 2
    BACE2
    AEPLC
    ALP56
    ASP1
    ASP21
    BAE2
    CDA13
    CEAP1
    DRAP
    605668
    934
    ENSG00000182240
    OTTHUMG00000086742
    Q9Y5Z0
    UNQ418/PRO852
    BACE2_HUMAN
    2331
    NM_012105|NM_138991|NM_138992
    NP_036237|NP_620476|NP_620477
    BETA-SECRETASE 2
    BETA SECRETASE 2 PRECURSOR (EC 3.4.23.45) (BETA-SITE APP-CLEAVING ENZYME 2) (ASPARTYL PROTEASE 1) (ASP 1) (ASP1) (MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 1) (MEMAPSIN-1) (DOWN REGION ASPARTIC PROTEASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9Y5Z0]

    Gene Info:

    GuideToPharmacology Gene Category Name A1: Pepsin
    GuideToPharmacology Gene Category ID 726
    GuideToPharmacology Gene Type enzyme
    Target Class Enzymes
    Target Subclass EC:3.4.23.45
    Human Readable Name PROTEASE
    Interpro Name Peptidase aspartic, active site
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR001969
    Interpro Type Active_site
    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Peptidase_aspartic_AS
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING"
    (5 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Competitive
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

    • Version: 90_38

    Alternate Names:
    BACE2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 27-June-2013

    Alternate Names:
    25825 Entrez Gene Id
    BACE2 Gene Symbol

    Gene Info:
    Human Readable Name PROTEASE

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    BETA SECRETASE 2 PRECURSOR (EC 3.4.23.45) (BETA-SITE APP-CLEAVING ENZYME 2) (ASPARTYL PROTEASE 1) (ASP 1) (ASP1) (MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 1) (MEMAPSIN-1) (DOWN REGION ASPARTIC PROTEASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9Y5Z0] Description
    ENSG00000182240 Ensembl Gene Id
    BACE2 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    beta-site APP-cleaving enzyme 2 HUGO Gene Name
    934 HUGO Gene ID
    BACE2 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name A1: Pepsin
    GuideToPharmacology Gene Category ID 726
    GuideToPharmacology Gene Type enzyme

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    BACE2_HUMAN Uniprot Id
    25825 Entrez Gene Id
    ENSG00000182240 Ensembl Gene Id

    Gene Info:
    Human Readable Name PROTEASE
    Interpro Name Peptidase aspartic, active site
    Uniprot Evidence 1: Evidence at protein level

    Publications:

    • Version: January-2014

    Alternate Names:
    BACE2 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.4.23.45

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    beta-site APP-cleaving enzyme 2 GuideToPharmacology Name
    Q9Y5Z0 UniProtKB ID

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000182240 Gene Symbol
    BACE2 Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q9Y5Z0 UniProtKB ID
    BACE2_HUMAN GO Gene Synonym
    AEPLC GO Gene Synonym

    Gene Info:

    Publications: