• BACE1 23621 Druggable Genome

    Alternate Names:

    23621
    BETA-SECRETASE 1
    BACE1
    ASP2
    BACE
    HSPC104
    604252
    933
    ENSG00000186318
    OTTHUMG00000160636
    KIAA1149
    BACE1_HUMAN
    P56817
    Aspartyl protease 2
    Beta-site amyloid precursor protein cleaving enzyme 1
    Memapsin-2
    Membrane-associated aspartic protease 2
    Asp 2
    Beta-site APP cleaving enzyme 1
    BETA-SECRETASE 1 PRECURSOR (EC 3.4.23.46) (BETA-SITE APP CLEAVING ENZYME 1) (BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1) (ASPARTYL PROTEASE 2) (ASP 2) (ASP2) (MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2) (MEMAPSIN-2). [SOURCE:UNIPROT/SWISSPROT;ACC:
    2330
    NP_001193978|NP_036236|NP_620427|NP_620428|NP_620429
    NM_001207049|NM_012104|NM_138971|NM_138972|NM_138973
    beta-site APP-cleaving enzyme 1
    TTDC00092
    BETA-SECRETASE
    BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME
    TRANSMEMBRANE ASPARTIC PROTEASE
    BETA-SITE ABETAPP-CLEAVING ENZYME
    BETA-SITE APP CLEAVING ENZYME
    BE0000988

    Gene Info:

    Human Readable Name PROTEASE
    Target Class Enzymes
    Target Subclass EC:3.4.23.46
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Peptidase aspartic, active site
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name Peptidase_aspartic_AS
    Interpro Type Active_site
    Interpro Acc IPR001969
    Uniprot Status Swiss-Prot
    GuideToPharmacology Gene Category Name A1: Pepsin
    GuideToPharmacology Gene Category ID 726
    GuideToPharmacology Gene Type enzyme
    Gene Biotype PROTEIN_CODING"
    (8 More Sources)